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Q5SHR1 (IF1_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-1
Gene names
Name:infA
Ordered Locus Names:TTHA1669
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length72 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity. HAMAP-Rule MF_00075

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00075.

Sequence similarities

Belongs to the IF-1 family.

Contains 1 S1-like domain.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7272Translation initiation factor IF-1 HAMAP-Rule MF_00075
PRO_0000095893

Regions

Domain1 – 7272S1-like

Secondary structure

........... 72
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5SHR1 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: 981E63B61223DDFC

FASTA728,234
        10         20         30         40         50         60 
MAKEKDTIRT EGVVTEALPN ATFRVKLDSG PEILAYISGK MRMHYIRILP GDRVVVEITP 

        70 
YDPTRGRIVY RK 

« Hide

References

[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008226 Genomic DNA. Translation: BAD71492.1.
RefSeqYP_144935.1. NC_006461.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1HR0X-ray3.20W2-72[»]
ProteinModelPortalQ5SHR1.
SMRQ5SHR1. Positions 2-72.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING300852.TTHA1669.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD71492; BAD71492; BAD71492.
GeneID3168806.
KEGGttj:TTHA1669.
PATRIC23958293. VBITheThe93045_1639.

Phylogenomic databases

eggNOGCOG0361.
HOGENOMHOG000221323.
KOK02518.
OMAKGRIIWR.
OrthoDBEOG6384SC.
PhylomeDBQ5SHR1.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-1708-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00075. IF_1.
InterProIPR012340. NA-bd_OB-fold.
IPR022967. RNA-binding_domain_S1.
IPR006196. RNA-binding_domain_S1_IF1.
IPR004368. TIF_IF1.
[Graphical view]
PfamPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTSM00316. S1. 1 hit.
[Graphical view]
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00008. infA. 1 hit.
PROSITEPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ5SHR1.

Entry information

Entry nameIF1_THET8
AccessionPrimary (citable) accession number: Q5SHR1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Translation initiation factors

List of translation initiation factor entries