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Q5SHR1

- IF1_THET8

UniProt

Q5SHR1 - IF1_THET8

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Protein

Translation initiation factor IF-1

Gene
infA, TTHA1669
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 By similarity.UniRule annotation

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-1708-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-1
Gene namesi
Name:infA
Ordered Locus Names:TTHA1669
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000532: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7272Translation initiation factor IF-1UniRule annotationPRO_0000095893Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA1669.

Structurei

Secondary structure

1
72
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi11 – 133
Turni19 – 213
Beta strandi26 – 305
Helixi39 – 435
Beta strandi53 – 575

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1HR0X-ray3.20W2-72[»]
ProteinModelPortaliQ5SHR1.
SMRiQ5SHR1. Positions 2-72.

Miscellaneous databases

EvolutionaryTraceiQ5SHR1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7272S1-likeAdd
BLAST

Sequence similaritiesi

Belongs to the IF-1 family.
Contains 1 S1-like domain.

Phylogenomic databases

eggNOGiCOG0361.
HOGENOMiHOG000221323.
KOiK02518.
OMAiKGRIIWR.
OrthoDBiEOG6384SC.
PhylomeDBiQ5SHR1.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
HAMAPiMF_00075. IF_1.
InterProiIPR012340. NA-bd_OB-fold.
IPR022967. RNA-binding_domain_S1.
IPR006196. RNA-binding_domain_S1_IF1.
IPR004368. TIF_IF1.
[Graphical view]
PfamiPF01176. eIF-1a. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00008. infA. 1 hit.
PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SHR1-1 [UniParc]FASTAAdd to Basket

« Hide

MAKEKDTIRT EGVVTEALPN ATFRVKLDSG PEILAYISGK MRMHYIRILP   50
GDRVVVEITP YDPTRGRIVY RK 72
Length:72
Mass (Da):8,234
Last modified:December 21, 2004 - v1
Checksum:i981E63B61223DDFC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008226 Genomic DNA. Translation: BAD71492.1.
RefSeqiYP_144935.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD71492; BAD71492; BAD71492.
GeneIDi3168806.
KEGGittj:TTHA1669.
PATRICi23958293. VBITheThe93045_1639.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008226 Genomic DNA. Translation: BAD71492.1 .
RefSeqi YP_144935.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1HR0 X-ray 3.20 W 2-72 [» ]
ProteinModelPortali Q5SHR1.
SMRi Q5SHR1. Positions 2-72.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 300852.TTHA1669.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD71492 ; BAD71492 ; BAD71492 .
GeneIDi 3168806.
KEGGi ttj:TTHA1669.
PATRICi 23958293. VBITheThe93045_1639.

Phylogenomic databases

eggNOGi COG0361.
HOGENOMi HOG000221323.
KOi K02518.
OMAi KGRIIWR.
OrthoDBi EOG6384SC.
PhylomeDBi Q5SHR1.

Enzyme and pathway databases

BioCyci TTHE300852:GH8R-1708-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q5SHR1.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
HAMAPi MF_00075. IF_1.
InterProi IPR012340. NA-bd_OB-fold.
IPR022967. RNA-binding_domain_S1.
IPR006196. RNA-binding_domain_S1_IF1.
IPR004368. TIF_IF1.
[Graphical view ]
Pfami PF01176. eIF-1a. 1 hit.
[Graphical view ]
SMARTi SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00008. infA. 1 hit.
PROSITEi PS50832. S1_IF1_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Thermus thermophilus HB8."
    Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB8 / ATCC 27634 / DSM 579.

Entry informationi

Entry nameiIF1_THET8
AccessioniPrimary (citable) accession number: Q5SHR1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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