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Q5SHR1

- IF1_THET8

UniProt

Q5SHR1 - IF1_THET8

Protein

Translation initiation factor IF-1

Gene

infA

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciTTHE300852:GH8R-1708-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-1UniRule annotation
    Gene namesi
    Name:infAUniRule annotation
    Ordered Locus Names:TTHA1669
    OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    Taxonomic identifieri300852 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000532: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7272Translation initiation factor IF-1PRO_0000095893Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi300852.TTHA1669.

    Structurei

    Secondary structure

    1
    72
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi11 – 133
    Turni19 – 213
    Beta strandi26 – 305
    Helixi39 – 435
    Beta strandi53 – 575

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1HR0X-ray3.20W2-72[»]
    ProteinModelPortaliQ5SHR1.
    SMRiQ5SHR1. Positions 2-72.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ5SHR1.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 7272S1-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the IF-1 family.UniRule annotation
    Contains 1 S1-like domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0361.
    HOGENOMiHOG000221323.
    KOiK02518.
    OMAiKGRIIWR.
    OrthoDBiEOG6384SC.
    PhylomeDBiQ5SHR1.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_00075. IF_1.
    InterProiIPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view]
    PfamiPF01176. eIF-1a. 1 hit.
    [Graphical view]
    SMARTiSM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00008. infA. 1 hit.
    PROSITEiPS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5SHR1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKDTIRT EGVVTEALPN ATFRVKLDSG PEILAYISGK MRMHYIRILP   50
    GDRVVVEITP YDPTRGRIVY RK 72
    Length:72
    Mass (Da):8,234
    Last modified:December 21, 2004 - v1
    Checksum:i981E63B61223DDFC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71492.1.
    RefSeqiYP_144935.1. NC_006461.1.

    Genome annotation databases

    EnsemblBacteriaiBAD71492; BAD71492; BAD71492.
    GeneIDi3168806.
    KEGGittj:TTHA1669.
    PATRICi23958293. VBITheThe93045_1639.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71492.1 .
    RefSeqi YP_144935.1. NC_006461.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1HR0 X-ray 3.20 W 2-72 [» ]
    ProteinModelPortali Q5SHR1.
    SMRi Q5SHR1. Positions 2-72.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 300852.TTHA1669.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD71492 ; BAD71492 ; BAD71492 .
    GeneIDi 3168806.
    KEGGi ttj:TTHA1669.
    PATRICi 23958293. VBITheThe93045_1639.

    Phylogenomic databases

    eggNOGi COG0361.
    HOGENOMi HOG000221323.
    KOi K02518.
    OMAi KGRIIWR.
    OrthoDBi EOG6384SC.
    PhylomeDBi Q5SHR1.

    Enzyme and pathway databases

    BioCyci TTHE300852:GH8R-1708-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q5SHR1.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_00075. IF_1.
    InterProi IPR012340. NA-bd_OB-fold.
    IPR022967. RNA-binding_domain_S1.
    IPR006196. RNA-binding_domain_S1_IF1.
    IPR004368. TIF_IF1.
    [Graphical view ]
    Pfami PF01176. eIF-1a. 1 hit.
    [Graphical view ]
    SMARTi SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00008. infA. 1 hit.
    PROSITEi PS50832. S1_IF1_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Thermus thermophilus HB8."
      Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB8 / ATCC 27634 / DSM 579.

    Entry informationi

    Entry nameiIF1_THET8
    AccessioniPrimary (citable) accession number: Q5SHR1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 30, 2005
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3