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Q5SHP9

- RL24_THET8

UniProt

Q5SHP9 - RL24_THET8

Protein

50S ribosomal protein L24

Gene

rplX

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.By similarity
    One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-KW
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE300852:GH8R-1720-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L24
    Gene namesi
    Name:rplX
    Ordered Locus Names:TTHA1681
    OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    Taxonomic identifieri300852 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000532: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11011050S ribosomal protein L24PRO_0000130741Add
    BLAST

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.

    Protein-protein interaction databases

    STRINGi300852.TTHA1681.

    Structurei

    Secondary structure

    1
    110
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi11 – 155
    Turni19 – 224
    Beta strandi24 – 318
    Helixi32 – 343
    Beta strandi36 – 394
    Beta strandi42 – 487
    Beta strandi51 – 555
    Beta strandi60 – 645
    Helixi69 – 713
    Beta strandi72 – 754
    Turni77 – 793
    Beta strandi85 – 895
    Beta strandi91 – 933
    Beta strandi95 – 1028
    Beta strandi105 – 1073

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1GIYX-ray5.50U1-110[»]
    1YL3X-ray5.50U65-68[»]
    2HGJX-ray5.00X1-110[»]
    2HGQX-ray5.50X1-110[»]
    2HGUX-ray4.51X1-110[»]
    2J01X-ray2.80Y1-110[»]
    2J03X-ray2.80Y1-110[»]
    2V47X-ray3.80Y1-110[»]
    2V49X-ray3.80Y1-110[»]
    2WDIX-ray3.30Y1-110[»]
    2WDJX-ray3.30Y1-110[»]
    2WDLX-ray3.50Y1-110[»]
    2WDNX-ray3.50Y1-110[»]
    2WH2X-ray3.45Y1-110[»]
    2WH4X-ray3.45Y1-110[»]
    2WRJX-ray3.60Y1-110[»]
    2WRLX-ray3.60Y1-110[»]
    2WROX-ray3.60Y1-110[»]
    2WRRX-ray3.60Y1-110[»]
    2X9SX-ray3.10Y1-110[»]
    2X9UX-ray3.10Y1-110[»]
    2XG0X-ray3.20Y1-110[»]
    2XG2X-ray3.20Y1-110[»]
    2XQEX-ray3.10Y1-110[»]
    2XTGelectron microscopy7.80Y1-110[»]
    2XUXelectron microscopy7.60Y1-110[»]
    2Y0VX-ray3.10Y1-110[»]
    2Y0XX-ray3.10Y1-110[»]
    2Y0ZX-ray3.10Y1-110[»]
    2Y11X-ray3.10Y1-110[»]
    2Y13X-ray3.10Y1-110[»]
    2Y15X-ray3.10Y1-110[»]
    2Y17X-ray3.10Y1-110[»]
    2Y19X-ray3.10Y1-110[»]
    3FINelectron microscopy6.40Y2-102[»]
    3HUXX-ray3.10Y1-110[»]
    3HUZX-ray3.10Y1-110[»]
    3I8FX-ray3.10U1-110[»]
    3I8IX-ray3.10U1-110[»]
    3I9CX-ray3.50U1-110[»]
    3I9EX-ray3.50U1-110[»]
    3KIRX-ray3.30Y1-110[»]
    3KITX-ray3.30Y1-110[»]
    3KIWX-ray3.60Y1-110[»]
    3KIYX-ray3.60Y1-110[»]
    3KNIX-ray3.00Y1-110[»]
    3KNKX-ray3.00Y1-110[»]
    3KNMX-ray3.45Y1-110[»]
    3KNOX-ray3.45Y1-110[»]
    3TVEX-ray3.10U2-103[»]
    3TVHX-ray3.10U2-103[»]
    3UXQX-ray3.20Y1-110[»]
    3UXRX-ray3.20Y1-110[»]
    3UYEX-ray3.00U1-110[»]
    3UYGX-ray3.00U1-110[»]
    3UZ1X-ray3.30U1-110[»]
    3UZ2X-ray3.30U1-110[»]
    3UZ8X-ray3.00U1-110[»]
    3UZ9X-ray3.00U1-110[»]
    3UZFX-ray3.30U1-110[»]
    3UZHX-ray3.30U1-110[»]
    3UZKX-ray3.30U1-110[»]
    3UZNX-ray3.30U1-110[»]
    3V23X-ray3.00Y1-110[»]
    3V25X-ray3.00Y1-110[»]
    3V27X-ray3.10Y1-110[»]
    3V29X-ray3.10Y1-110[»]
    3V2DX-ray2.70Y1-110[»]
    3V2FX-ray2.70Y1-110[»]
    3V6WX-ray3.90Y1-110[»]
    3V6XX-ray3.90Y1-110[»]
    3ZN9X-ray3.10Y1-110[»]
    3ZNEX-ray3.10Y1-110[»]
    3ZVPX-ray3.80Y1-110[»]
    4ABSX-ray3.10Y1-110[»]
    4B8GX-ray3.70Y1-110[»]
    4B8IX-ray3.70Y1-110[»]
    4BTDX-ray2.95Y2-110[»]
    4BYCX-ray3.35Y1-110[»]
    4BYEX-ray3.35Y1-110[»]
    4DHAX-ray3.20Y1-110[»]
    4DHCX-ray3.20Y1-110[»]
    4EJBX-ray3.52Y1-110[»]
    4EJCX-ray3.52Y1-110[»]
    4G5LX-ray3.30U1-110[»]
    4G5NX-ray3.30U1-110[»]
    4G5UX-ray3.10U1-110[»]
    4G5WX-ray3.10U1-110[»]
    4JUXX-ray2.86Y1-110[»]
    4K0MX-ray3.30Y2-101[»]
    4K0QX-ray3.30Y2-101[»]
    4NVVX-ray3.00Y1-110[»]
    4NVXX-ray3.00Y1-110[»]
    4NVZX-ray3.10Y1-110[»]
    4NW1X-ray3.10Y1-110[»]
    ProteinModelPortaliQ5SHP9.
    SMRiQ5SHP9. Positions 1-110.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ5SHP9.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L24P family.Curated

    Phylogenomic databases

    eggNOGiCOG0198.
    HOGENOMiHOG000039891.
    KOiK02895.
    OMAiLYCNKCK.
    OrthoDBiEOG6FFSDM.
    PhylomeDBiQ5SHP9.

    Family and domain databases

    Gene3Di2.30.30.30. 1 hit.
    HAMAPiMF_01326_B. Ribosomal_L24_B.
    InterProiIPR005824. KOW.
    IPR014722. Rib_L2_dom2.
    IPR003256. Ribosomal_L24.
    IPR005825. Ribosomal_L24/26_CS.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view]
    PANTHERiPTHR12903. PTHR12903. 1 hit.
    PfamiPF00467. KOW. 1 hit.
    [Graphical view]
    SMARTiSM00739. KOW. 1 hit.
    [Graphical view]
    SUPFAMiSSF50104. SSF50104. 1 hit.
    TIGRFAMsiTIGR01079. rplX_bact. 1 hit.
    PROSITEiPS01108. RIBOSOMAL_L24. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5SHP9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRVKMHVKKG DTVLVASGKY KGRVGKVKEV LPKKYAVIVE GVNIVKKAVR    50
    VSPKYPQGGF IEKEAPLHAS KVRPICPACG KPTRVRKKFL ENGKKIRVCA 100
    KCGGALDTEE 110
    Length:110
    Mass (Da):12,057
    Last modified:December 21, 2004 - v1
    Checksum:iA9E773D9A86B819A
    GO

    Mass spectrometryi

    Molecular mass is 12057 Da from positions 1 - 110. Determined by MALDI. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71504.1.
    RefSeqiWP_011173707.1. NC_006461.1.
    YP_144947.1. NC_006461.1.

    Genome annotation databases

    EnsemblBacteriaiBAD71504; BAD71504; BAD71504.
    GeneIDi3169836.
    KEGGittj:TTHA1681.
    PATRICi23958317. VBITheThe93045_1651.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71504.1 .
    RefSeqi WP_011173707.1. NC_006461.1.
    YP_144947.1. NC_006461.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1GIY X-ray 5.50 U 1-110 [» ]
    1YL3 X-ray 5.50 U 65-68 [» ]
    2HGJ X-ray 5.00 X 1-110 [» ]
    2HGQ X-ray 5.50 X 1-110 [» ]
    2HGU X-ray 4.51 X 1-110 [» ]
    2J01 X-ray 2.80 Y 1-110 [» ]
    2J03 X-ray 2.80 Y 1-110 [» ]
    2V47 X-ray 3.80 Y 1-110 [» ]
    2V49 X-ray 3.80 Y 1-110 [» ]
    2WDI X-ray 3.30 Y 1-110 [» ]
    2WDJ X-ray 3.30 Y 1-110 [» ]
    2WDL X-ray 3.50 Y 1-110 [» ]
    2WDN X-ray 3.50 Y 1-110 [» ]
    2WH2 X-ray 3.45 Y 1-110 [» ]
    2WH4 X-ray 3.45 Y 1-110 [» ]
    2WRJ X-ray 3.60 Y 1-110 [» ]
    2WRL X-ray 3.60 Y 1-110 [» ]
    2WRO X-ray 3.60 Y 1-110 [» ]
    2WRR X-ray 3.60 Y 1-110 [» ]
    2X9S X-ray 3.10 Y 1-110 [» ]
    2X9U X-ray 3.10 Y 1-110 [» ]
    2XG0 X-ray 3.20 Y 1-110 [» ]
    2XG2 X-ray 3.20 Y 1-110 [» ]
    2XQE X-ray 3.10 Y 1-110 [» ]
    2XTG electron microscopy 7.80 Y 1-110 [» ]
    2XUX electron microscopy 7.60 Y 1-110 [» ]
    2Y0V X-ray 3.10 Y 1-110 [» ]
    2Y0X X-ray 3.10 Y 1-110 [» ]
    2Y0Z X-ray 3.10 Y 1-110 [» ]
    2Y11 X-ray 3.10 Y 1-110 [» ]
    2Y13 X-ray 3.10 Y 1-110 [» ]
    2Y15 X-ray 3.10 Y 1-110 [» ]
    2Y17 X-ray 3.10 Y 1-110 [» ]
    2Y19 X-ray 3.10 Y 1-110 [» ]
    3FIN electron microscopy 6.40 Y 2-102 [» ]
    3HUX X-ray 3.10 Y 1-110 [» ]
    3HUZ X-ray 3.10 Y 1-110 [» ]
    3I8F X-ray 3.10 U 1-110 [» ]
    3I8I X-ray 3.10 U 1-110 [» ]
    3I9C X-ray 3.50 U 1-110 [» ]
    3I9E X-ray 3.50 U 1-110 [» ]
    3KIR X-ray 3.30 Y 1-110 [» ]
    3KIT X-ray 3.30 Y 1-110 [» ]
    3KIW X-ray 3.60 Y 1-110 [» ]
    3KIY X-ray 3.60 Y 1-110 [» ]
    3KNI X-ray 3.00 Y 1-110 [» ]
    3KNK X-ray 3.00 Y 1-110 [» ]
    3KNM X-ray 3.45 Y 1-110 [» ]
    3KNO X-ray 3.45 Y 1-110 [» ]
    3TVE X-ray 3.10 U 2-103 [» ]
    3TVH X-ray 3.10 U 2-103 [» ]
    3UXQ X-ray 3.20 Y 1-110 [» ]
    3UXR X-ray 3.20 Y 1-110 [» ]
    3UYE X-ray 3.00 U 1-110 [» ]
    3UYG X-ray 3.00 U 1-110 [» ]
    3UZ1 X-ray 3.30 U 1-110 [» ]
    3UZ2 X-ray 3.30 U 1-110 [» ]
    3UZ8 X-ray 3.00 U 1-110 [» ]
    3UZ9 X-ray 3.00 U 1-110 [» ]
    3UZF X-ray 3.30 U 1-110 [» ]
    3UZH X-ray 3.30 U 1-110 [» ]
    3UZK X-ray 3.30 U 1-110 [» ]
    3UZN X-ray 3.30 U 1-110 [» ]
    3V23 X-ray 3.00 Y 1-110 [» ]
    3V25 X-ray 3.00 Y 1-110 [» ]
    3V27 X-ray 3.10 Y 1-110 [» ]
    3V29 X-ray 3.10 Y 1-110 [» ]
    3V2D X-ray 2.70 Y 1-110 [» ]
    3V2F X-ray 2.70 Y 1-110 [» ]
    3V6W X-ray 3.90 Y 1-110 [» ]
    3V6X X-ray 3.90 Y 1-110 [» ]
    3ZN9 X-ray 3.10 Y 1-110 [» ]
    3ZNE X-ray 3.10 Y 1-110 [» ]
    3ZVP X-ray 3.80 Y 1-110 [» ]
    4ABS X-ray 3.10 Y 1-110 [» ]
    4B8G X-ray 3.70 Y 1-110 [» ]
    4B8I X-ray 3.70 Y 1-110 [» ]
    4BTD X-ray 2.95 Y 2-110 [» ]
    4BYC X-ray 3.35 Y 1-110 [» ]
    4BYE X-ray 3.35 Y 1-110 [» ]
    4DHA X-ray 3.20 Y 1-110 [» ]
    4DHC X-ray 3.20 Y 1-110 [» ]
    4EJB X-ray 3.52 Y 1-110 [» ]
    4EJC X-ray 3.52 Y 1-110 [» ]
    4G5L X-ray 3.30 U 1-110 [» ]
    4G5N X-ray 3.30 U 1-110 [» ]
    4G5U X-ray 3.10 U 1-110 [» ]
    4G5W X-ray 3.10 U 1-110 [» ]
    4JUX X-ray 2.86 Y 1-110 [» ]
    4K0M X-ray 3.30 Y 2-101 [» ]
    4K0Q X-ray 3.30 Y 2-101 [» ]
    4NVV X-ray 3.00 Y 1-110 [» ]
    4NVX X-ray 3.00 Y 1-110 [» ]
    4NVZ X-ray 3.10 Y 1-110 [» ]
    4NW1 X-ray 3.10 Y 1-110 [» ]
    ProteinModelPortali Q5SHP9.
    SMRi Q5SHP9. Positions 1-110.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 300852.TTHA1681.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD71504 ; BAD71504 ; BAD71504 .
    GeneIDi 3169836.
    KEGGi ttj:TTHA1681.
    PATRICi 23958317. VBITheThe93045_1651.

    Phylogenomic databases

    eggNOGi COG0198.
    HOGENOMi HOG000039891.
    KOi K02895.
    OMAi LYCNKCK.
    OrthoDBi EOG6FFSDM.
    PhylomeDBi Q5SHP9.

    Enzyme and pathway databases

    BioCyci TTHE300852:GH8R-1720-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q5SHP9.

    Family and domain databases

    Gene3Di 2.30.30.30. 1 hit.
    HAMAPi MF_01326_B. Ribosomal_L24_B.
    InterProi IPR005824. KOW.
    IPR014722. Rib_L2_dom2.
    IPR003256. Ribosomal_L24.
    IPR005825. Ribosomal_L24/26_CS.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view ]
    PANTHERi PTHR12903. PTHR12903. 1 hit.
    Pfami PF00467. KOW. 1 hit.
    [Graphical view ]
    SMARTi SM00739. KOW. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50104. SSF50104. 1 hit.
    TIGRFAMsi TIGR01079. rplX_bact. 1 hit.
    PROSITEi PS01108. RIBOSOMAL_L24. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Thermus thermophilus HB8."
      Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB8 / ATCC 27634 / DSM 579.
    2. "The isolation and complete amino acid sequence of the ribosomal protein L36 from Thermus thermophilus and its zinc-binding motif."
      Boysen R.I., Lorenz S., Kim J.S., Schroeder W.F.K.J., Erdmann V.A.
      Endocyt. Cell Res. 11:41-58(1995)
      Cited for: PROTEIN SEQUENCE OF 1-44.
    3. "Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus."
      Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T.
      Biol. Chem. 381:1079-1087(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-24.
    4. "Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
      Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
      Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: MASS SPECTROMETRY.
    5. "The path of messenger RNA through the ribosome."
      Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
      Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
    6. Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.

    Entry informationi

    Entry nameiRL24_THET8
    AccessioniPrimary (citable) accession number: Q5SHP9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3