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Q5SHP2 (RS19_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein S19
Gene names
Name:rpsS
Ordered Locus Names:TTHA1688
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length93 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Located at the top of the head of the 30S subunit, extending towards the 50S subunit, which it may contact in the 70S complex. Contacts several RNA helices of the 16S rRNA. HAMAP-Rule MF_00531

Subunit structure

Part of the 30S ribosomal subunit. Forms a loose dimer with protein S13. Ref.4 Ref.5 Ref.6 Ref.7 Ref.9 Ref.10 Ref.12 Ref.13

Sequence similarities

Belongs to the ribosomal protein S19P family.

Mass spectrometry

Molecular mass is 10451 Da from positions 2 - 93. Determined by MALDI. Ref.3

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.2
Chain2 – 939230S ribosomal protein S19 HAMAP-Rule MF_00531
PRO_0000129927

Secondary structure

........................ 93
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5SHP2 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: D77C0FC2D4D2DE04

FASTA9310,581
        10         20         30         40         50         60 
MPRSLKKGVF VDDHLLEKVL ELNAKGEKRL IKTWSRRSTI VPEMVGHTIA VYNGKQHVPV 

        70         80         90 
YITENMVGHK LGEFAPTRTY RGHGKEAKAT KKK 

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
[2]"Purification and characterization of the 30S ribosomal proteins from the bacterium Thermus thermophilus."
Tsiboli P., Herfurth E., Choli T.
Eur. J. Biochem. 226:169-177(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-31.
[3]"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: MASS SPECTROMETRY.
[4]"Structure of the 30S ribosomal subunit."
Wimberly B.T., Brodersen D.E., Clemons W.M. Jr., Morgan-Warren R.J., Carter A.P., Vonrhein C., Hartsch T., Ramakrishnan V.
Nature 407:327-339(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
[5]"Structure of functionally activated small ribosomal subunit at 3.3 A resolution."
Schluenzen F., Tocilj A., Zarivach R., Harms J., Gluehmann M., Janell D., Bashan A., Bartels H., Agmon I., Franceschi F., Yonath A.
Cell 102:615-623(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[6]"The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit."
Brodersen D.E., Clemons W.M. Jr., Carter A.P., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V.
Cell 103:1143-1154(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[7]"Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics."
Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V.
Nature 407:340-348(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 30S SUBUNIT.
[8]"The path of messenger RNA through the ribosome."
Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
[9]"Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3."
Pioletti M., Schluenzen F., Harms J., Zarivach R., Gluehmann M., Avila H., Bashan A., Bartels H., Auerbach T., Jacobi C., Hartsch T., Yonath A., Franceschi F.
EMBO J. 20:1829-1839(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[10]"Crystal structure of an initiation factor bound to the 30S ribosomal subunit."
Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Hartsch T., Wimberly B.T., Ramakrishnan V.
Science 291:498-501(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[11]"Crystal structure of the ribosome at 5.5 A resolution."
Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F.
Science 292:883-896(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.
[12]"Recognition of cognate transfer RNA by the 30S ribosomal subunit."
Ogle J.M., Brodersen D.E., Clemons W.M. Jr., Tarry M.J., Carter A.P., Ramakrishnan V.
Science 292:897-902(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.11 ANGSTROMS) OF THE 30S SUBUNIT.
[13]"Crystal structure of the 30S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16S RNA."
Brodersen D.E., Clemons W.M. Jr., Carter A.P., Wimberly B.T., Ramakrishnan V.
J. Mol. Biol. 316:725-768(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008226 Genomic DNA. Translation: BAD71511.1.
RefSeqYP_144954.1. NC_006461.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1FJGX-ray3.00S1-93[»]
1FKAX-ray3.30S1-93[»]
1GIXX-ray5.50V1-93[»]
1HNWX-ray3.40S1-93[»]
1HNXX-ray3.40S1-93[»]
1HNZX-ray3.30S1-93[»]
1HR0X-ray3.20S1-93[»]
1I94X-ray3.20S2-93[»]
1I95X-ray4.50S2-93[»]
1I96X-ray4.20S2-93[»]
1I97X-ray4.50S2-93[»]
1IBKX-ray3.31S1-93[»]
1IBLX-ray3.11S1-93[»]
1IBMX-ray3.31S1-93[»]
1J5EX-ray3.05S2-93[»]
1JGOX-ray5.60V1-93[»]
1JGPX-ray7.00V1-93[»]
1JGQX-ray5.00V1-93[»]
1L1Umodel-S1-81[»]
1ML5electron microscopy14.00V1-93[»]
1N32X-ray3.00S2-93[»]
1N33X-ray3.35S2-93[»]
1N34X-ray3.80S2-93[»]
1N36X-ray3.65S2-93[»]
1PNSX-ray8.70S2-81[»]
1PNXX-ray9.50S2-81[»]
1XMOX-ray3.25S1-93[»]
1XMQX-ray3.00S1-93[»]
1XNQX-ray3.05S1-93[»]
1XNRX-ray3.10S1-93[»]
1YL4X-ray5.50V1-93[»]
2B64X-ray5.90S1-93[»]
2B9MX-ray6.76S1-93[»]
2B9OX-ray6.46S1-93[»]
2E5LX-ray3.30S2-93[»]
2F4VX-ray3.80S1-93[»]
2HGIX-ray5.00V1-93[»]
2HGPX-ray5.50V1-93[»]
2HGRX-ray4.51V1-93[»]
2HHHX-ray3.35S1-93[»]
2J00X-ray2.80S2-92[»]
2J02X-ray2.80S2-93[»]
2OW8X-ray3.71t1-93[»]
2UU9X-ray3.10S2-93[»]
2UUAX-ray2.90S2-93[»]
2UUBX-ray2.80S2-93[»]
2UUCX-ray3.10S2-93[»]
2UXBX-ray3.10S2-93[»]
2UXCX-ray2.90S2-93[»]
2UXDX-ray3.20S2-93[»]
2V46X-ray3.50S2-93[»]
2V48X-ray3.50S2-93[»]
2VQEX-ray2.50S1-93[»]
2VQFX-ray2.90S1-93[»]
2WDGX-ray3.30S1-93[»]
2WDHX-ray3.30S1-93[»]
2WDKX-ray3.50S1-93[»]
2WDMX-ray3.50S1-93[»]
2WH1X-ray3.45S1-93[»]
2WH3X-ray3.45S1-93[»]
2WRIX-ray3.60S1-93[»]
2WRKX-ray3.60S1-93[»]
2WRNX-ray3.60S1-93[»]
2WRQX-ray3.60S1-93[»]
2X9RX-ray3.10S1-93[»]
2X9TX-ray3.10S1-93[»]
2XFZX-ray3.20S1-93[»]
2XG1X-ray3.20S1-93[»]
2XQDX-ray3.10S1-93[»]
2XSYelectron microscopy7.80S1-93[»]
2XUYelectron microscopy7.60S1-93[»]
2Y0UX-ray3.10S1-93[»]
2Y0WX-ray3.10S1-93[»]
2Y0YX-ray3.10S1-93[»]
2Y10X-ray3.10S1-93[»]
2Y12X-ray3.10S1-93[»]
2Y14X-ray3.10S1-93[»]
2Y16X-ray3.10S1-93[»]
2Y18X-ray3.10S1-93[»]
2ZM6X-ray3.30S2-93[»]
3A1PX-ray2.30B/D1-93[»]
3FICelectron microscopy6.40S4-82[»]
3HUWX-ray3.10S1-93[»]
3HUYX-ray3.10S1-93[»]
3I8GX-ray3.10V1-93[»]
3I8HX-ray3.10V1-93[»]
3I9BX-ray3.50V1-93[»]
3I9DX-ray3.50V1-93[»]
3KIQX-ray3.30s1-93[»]
3KISX-ray3.30s1-93[»]
3KIUX-ray3.60s1-93[»]
3KIXX-ray3.60s1-93[»]
3KNHX-ray3.00S1-93[»]
3KNJX-ray3.15S1-93[»]
3KNLX-ray3.45S1-93[»]
3KNNX-ray3.45S1-93[»]
3OGEX-ray3.00S1-93[»]
3OGYX-ray3.00S1-93[»]
3OHCX-ray3.00S1-93[»]
3OHDX-ray3.00S1-93[»]
3OHYX-ray3.00S1-93[»]
3OI0X-ray3.00S1-93[»]
3OI2X-ray3.10S1-93[»]
3OI4X-ray3.10S1-93[»]
3OTOX-ray3.69S1-93[»]
3T1HX-ray3.11S1-93[»]
3T1YX-ray2.80S1-93[»]
3TVFX-ray3.10V1-93[»]
3TVGX-ray3.10V1-93[»]
3UXSX-ray3.20S1-93[»]
3UXTX-ray3.20S1-93[»]
3UYDX-ray3.00V1-93[»]
3UYFX-ray3.00V1-93[»]
3UZ3X-ray3.30V1-93[»]
3UZ4X-ray3.30V1-93[»]
3UZ6X-ray3.00V1-93[»]
3UZ7X-ray3.00V1-93[»]
3UZGX-ray3.30V1-93[»]
3UZIX-ray3.30V1-93[»]
3UZLX-ray3.30V1-93[»]
3UZMX-ray3.30V1-93[»]
3V22X-ray3.00S1-93[»]
3V24X-ray3.00S1-93[»]
3V26X-ray3.10S1-93[»]
3V28X-ray3.10S1-93[»]
3V2CX-ray2.70S1-93[»]
3V2EX-ray2.70S1-93[»]
3V6UX-ray3.90S1-93[»]
3V6VX-ray3.90S1-93[»]
3ZN7X-ray3.10S1-93[»]
3ZNDX-ray3.10S1-93[»]
3ZVOX-ray3.80S1-93[»]
4ABRX-ray3.10S1-93[»]
4AQYX-ray3.50S2-93[»]
4B3MX-ray2.90S2-93[»]
4B3RX-ray3.00S2-93[»]
4B3SX-ray3.15S2-93[»]
4B3TX-ray3.00S2-93[»]
4B8FX-ray3.70S1-93[»]
4B8HX-ray3.70S1-93[»]
4BYDX-ray3.35S1-93[»]
4CR1X-ray2.95S1-93[»]
4DH9X-ray3.20S1-93[»]
4DHBX-ray3.20S1-93[»]
4DR1X-ray3.60S1-93[»]
4DR2X-ray3.25S1-93[»]
4DR3X-ray3.35S1-93[»]
4DR4X-ray3.97S1-93[»]
4DR5X-ray3.45S1-93[»]
4DR6X-ray3.30S1-93[»]
4DR7X-ray3.75S1-93[»]
4DUYX-ray3.39S1-93[»]
4DUZX-ray3.65S1-93[»]
4DV0X-ray3.85S1-93[»]
4DV1X-ray3.85S1-93[»]
4DV2X-ray3.65S1-93[»]
4DV3X-ray3.55S1-93[»]
4DV4X-ray3.65S1-93[»]
4DV5X-ray3.68S1-93[»]
4DV6X-ray3.30S1-93[»]
4DV7X-ray3.29S1-93[»]
4EJ9X-ray3.52S1-93[»]
4EJAX-ray3.52S1-93[»]
4G5KX-ray3.30V1-93[»]
4G5MX-ray3.30V1-93[»]
4G5TX-ray3.10V1-93[»]
4G5VX-ray3.10V1-93[»]
4GKJX-ray3.30S2-81[»]
4GKKX-ray3.20S2-81[»]
4JI0X-ray3.49S1-93[»]
4JI1X-ray3.14S1-93[»]
4JI2X-ray3.64S1-93[»]
4JI3X-ray3.35S1-93[»]
4JI4X-ray3.69S1-93[»]
4JI5X-ray3.85S1-93[»]
4JI6X-ray3.55S1-93[»]
4JI7X-ray3.50S1-93[»]
4JI8X-ray3.74S1-93[»]
4JUWX-ray2.86S4-81[»]
4JV5X-ray3.16S4-81[»]
4JYAX-ray3.10S4-81[»]
4K0KX-ray3.40S4-82[»]
4K0LX-ray3.30S4-81[»]
4K0PX-ray3.30S4-81[»]
4KHPX-ray3.10S4-81[»]
4NVUX-ray3.00S1-93[»]
4NVWX-ray3.00S1-93[»]
4NVYX-ray3.10S1-93[»]
4NW0X-ray3.10S1-93[»]
4NXMX-ray3.65S1-93[»]
4NXNX-ray3.54S1-93[»]
4OX9X-ray3.80S2-93[»]
ProteinModelPortalQ5SHP2.
SMRQ5SHP2. Positions 2-88.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING300852.TTHA1688.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD71511; BAD71511; BAD71511.
GeneID3167860.
KEGGttj:TTHA1688.
PATRIC23958331. VBITheThe93045_1658.

Phylogenomic databases

eggNOGCOG0185.
HOGENOMHOG000111560.
KOK02965.
OMAFIDHHLL.
OrthoDBEOG61S365.
PhylomeDBQ5SHP2.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-1727-MONOMER.

Family and domain databases

Gene3D3.30.860.10. 1 hit.
HAMAPMF_00531. Ribosomal_S19.
InterProIPR002222. Ribosomal_S19.
IPR005732. Ribosomal_S19_bac-type.
IPR020934. Ribosomal_S19_CS.
IPR023575. Ribosomal_S19_SF.
[Graphical view]
PANTHERPTHR11880. PTHR11880. 1 hit.
PfamPF00203. Ribosomal_S19. 1 hit.
[Graphical view]
PIRSFPIRSF002144. Ribosomal_S19. 1 hit.
PRINTSPR00975. RIBOSOMALS19.
SUPFAMSSF54570. SSF54570. 1 hit.
TIGRFAMsTIGR01050. rpsS_bact. 1 hit.
PROSITEPS00323. RIBOSOMAL_S19. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ5SHP2.

Entry information

Entry nameRS19_THET8
AccessionPrimary (citable) accession number: Q5SHP2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 93 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references