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Q5SHP0

- RL23_THET8

UniProt

Q5SHP0 - RL23_THET8

Protein

50S ribosomal protein L23

Gene

rplW

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.UniRule annotation

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. rRNA binding Source: UniProtKB-HAMAP
    3. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciTTHE300852:GH8R-1729-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L23UniRule annotation
    Gene namesi
    Name:rplWUniRule annotation
    Ordered Locus Names:TTHA1690
    OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    Taxonomic identifieri300852 [NCBI]
    Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
    ProteomesiUP000000532: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 969650S ribosomal protein L23PRO_0000129427Add
    BLAST

    Interactioni

    Subunit structurei

    Contacts protein L29, and trigger factor when it is bound to the ribosome By similarity. Part of the 50S ribosomal subunit.By similarity

    Protein-protein interaction databases

    STRINGi300852.TTHA1690.

    Structurei

    Secondary structure

    1
    96
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi4 – 74
    Beta strandi8 – 114
    Helixi15 – 184
    Turni19 – 246
    Beta strandi25 – 306
    Beta strandi32 – 343
    Helixi36 – 4712
    Beta strandi51 – 599
    Beta strandi63 – 664
    Beta strandi69 – 724
    Beta strandi76 – 838
    Beta strandi88 – 914
    Helixi92 – 943

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1GIYX-ray5.50T1-96[»]
    1YL3X-ray5.50T1-96[»]
    2J01X-ray2.80X1-96[»]
    2J03X-ray2.80X1-96[»]
    2V47X-ray3.80X1-96[»]
    2V49X-ray3.80X1-96[»]
    2WDIX-ray3.30X1-96[»]
    2WDJX-ray3.30X1-96[»]
    2WDLX-ray3.50X1-96[»]
    2WDNX-ray3.50X1-96[»]
    2WH2X-ray3.45X1-96[»]
    2WH4X-ray3.45X1-96[»]
    2WRJX-ray3.60X1-96[»]
    2WRLX-ray3.60X1-96[»]
    2WROX-ray3.60X1-96[»]
    2WRRX-ray3.60X1-96[»]
    2X9SX-ray3.10X1-96[»]
    2X9UX-ray3.10X1-96[»]
    2XG0X-ray3.20X1-96[»]
    2XG2X-ray3.20X1-96[»]
    2XQEX-ray3.10X1-96[»]
    2XTGelectron microscopy7.80X1-96[»]
    2XUXelectron microscopy7.60X1-96[»]
    2Y0VX-ray3.10X1-96[»]
    2Y0XX-ray3.10X1-96[»]
    2Y0ZX-ray3.10X1-96[»]
    2Y11X-ray3.10X1-96[»]
    2Y13X-ray3.10X1-96[»]
    2Y15X-ray3.10X1-96[»]
    2Y17X-ray3.10X1-96[»]
    2Y19X-ray3.10X1-96[»]
    3FINelectron microscopy6.40X3-95[»]
    3HUXX-ray3.10X1-96[»]
    3HUZX-ray3.10X1-96[»]
    3I8FX-ray3.10T1-96[»]
    3I8IX-ray3.10T1-96[»]
    3I9CX-ray3.50T1-96[»]
    3I9EX-ray3.50T1-96[»]
    3KIRX-ray3.30X1-96[»]
    3KITX-ray3.30X1-96[»]
    3KIWX-ray3.60X1-96[»]
    3KIYX-ray3.60X1-96[»]
    3KNIX-ray3.00X1-96[»]
    3KNKX-ray3.00X1-96[»]
    3KNMX-ray3.45X1-96[»]
    3KNOX-ray3.45X1-96[»]
    3TVEX-ray3.10T3-94[»]
    3TVHX-ray3.10T3-94[»]
    3UXQX-ray3.20X1-96[»]
    3UXRX-ray3.20X1-96[»]
    3UYEX-ray3.00T1-96[»]
    3UYGX-ray3.00T1-96[»]
    3UZ1X-ray3.30T1-96[»]
    3UZ2X-ray3.30T1-96[»]
    3UZ8X-ray3.00T1-96[»]
    3UZ9X-ray3.00T1-96[»]
    3UZFX-ray3.30T1-96[»]
    3UZHX-ray3.30T1-96[»]
    3UZKX-ray3.30T1-96[»]
    3UZNX-ray3.30T1-96[»]
    3V23X-ray3.00X1-96[»]
    3V25X-ray3.00X1-96[»]
    3V27X-ray3.10X1-96[»]
    3V29X-ray3.10X1-96[»]
    3V2DX-ray2.70X1-96[»]
    3V2FX-ray2.70X1-96[»]
    3V6WX-ray3.90X1-96[»]
    3V6XX-ray3.90X1-96[»]
    3ZN9X-ray3.10X1-96[»]
    3ZNEX-ray3.10X1-96[»]
    3ZVPX-ray3.80X1-96[»]
    4ABSX-ray3.10X1-96[»]
    4B8GX-ray3.70X1-96[»]
    4B8IX-ray3.70X1-96[»]
    4BTDX-ray2.95X2-96[»]
    4BYCX-ray3.35X1-96[»]
    4BYEX-ray3.35X1-96[»]
    4DHAX-ray3.20X1-96[»]
    4DHCX-ray3.20X1-96[»]
    4EJBX-ray3.52X1-96[»]
    4EJCX-ray3.52X1-96[»]
    4G5LX-ray3.30T1-96[»]
    4G5NX-ray3.30T1-96[»]
    4G5UX-ray3.10T1-96[»]
    4G5WX-ray3.10T1-96[»]
    4JUXX-ray2.86X1-96[»]
    4K0MX-ray3.30X3-94[»]
    4K0QX-ray3.30X3-94[»]
    4NVVX-ray3.00X1-96[»]
    4NVXX-ray3.00X1-96[»]
    4NVZX-ray3.10X1-96[»]
    4NW1X-ray3.10X1-96[»]
    ProteinModelPortaliQ5SHP0.
    SMRiQ5SHP0. Positions 1-96.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ5SHP0.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L23P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0089.
    HOGENOMiHOG000231366.
    KOiK02892.
    OMAiTAGMMND.
    OrthoDBiEOG6HTP4P.
    PhylomeDBiQ5SHP0.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    HAMAPiMF_01369_B. Ribosomal_L23_B.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR013025. Ribosomal_L25/23.
    [Graphical view]
    PfamiPF00276. Ribosomal_L23. 1 hit.
    [Graphical view]
    SUPFAMiSSF54189. SSF54189. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5SHP0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTAYDVILA PVLSEKAYAG FAEGKYTFWV HPKATKTEIK NAVETAFKVK   50
    VVKVNTLHVR GKKKRLGRYL GKRPDRKKAI VQVAPGQKIE ALEGLI 96
    Length:96
    Mass (Da):10,737
    Last modified:December 21, 2004 - v1
    Checksum:i28ABA3C2D83A102A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti18 – 181Y → R AA sequence (PubMed:11154066)Curated

    Mass spectrometryi

    Molecular mass is 10737 Da from positions 1 - 96. Determined by MALDI. 1 Publication

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71513.1.
    RefSeqiYP_144956.1. NC_006461.1.

    Genome annotation databases

    EnsemblBacteriaiBAD71513; BAD71513; BAD71513.
    GeneIDi3168722.
    KEGGittj:TTHA1690.
    PATRICi23958335. VBITheThe93045_1660.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008226 Genomic DNA. Translation: BAD71513.1 .
    RefSeqi YP_144956.1. NC_006461.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1GIY X-ray 5.50 T 1-96 [» ]
    1YL3 X-ray 5.50 T 1-96 [» ]
    2J01 X-ray 2.80 X 1-96 [» ]
    2J03 X-ray 2.80 X 1-96 [» ]
    2V47 X-ray 3.80 X 1-96 [» ]
    2V49 X-ray 3.80 X 1-96 [» ]
    2WDI X-ray 3.30 X 1-96 [» ]
    2WDJ X-ray 3.30 X 1-96 [» ]
    2WDL X-ray 3.50 X 1-96 [» ]
    2WDN X-ray 3.50 X 1-96 [» ]
    2WH2 X-ray 3.45 X 1-96 [» ]
    2WH4 X-ray 3.45 X 1-96 [» ]
    2WRJ X-ray 3.60 X 1-96 [» ]
    2WRL X-ray 3.60 X 1-96 [» ]
    2WRO X-ray 3.60 X 1-96 [» ]
    2WRR X-ray 3.60 X 1-96 [» ]
    2X9S X-ray 3.10 X 1-96 [» ]
    2X9U X-ray 3.10 X 1-96 [» ]
    2XG0 X-ray 3.20 X 1-96 [» ]
    2XG2 X-ray 3.20 X 1-96 [» ]
    2XQE X-ray 3.10 X 1-96 [» ]
    2XTG electron microscopy 7.80 X 1-96 [» ]
    2XUX electron microscopy 7.60 X 1-96 [» ]
    2Y0V X-ray 3.10 X 1-96 [» ]
    2Y0X X-ray 3.10 X 1-96 [» ]
    2Y0Z X-ray 3.10 X 1-96 [» ]
    2Y11 X-ray 3.10 X 1-96 [» ]
    2Y13 X-ray 3.10 X 1-96 [» ]
    2Y15 X-ray 3.10 X 1-96 [» ]
    2Y17 X-ray 3.10 X 1-96 [» ]
    2Y19 X-ray 3.10 X 1-96 [» ]
    3FIN electron microscopy 6.40 X 3-95 [» ]
    3HUX X-ray 3.10 X 1-96 [» ]
    3HUZ X-ray 3.10 X 1-96 [» ]
    3I8F X-ray 3.10 T 1-96 [» ]
    3I8I X-ray 3.10 T 1-96 [» ]
    3I9C X-ray 3.50 T 1-96 [» ]
    3I9E X-ray 3.50 T 1-96 [» ]
    3KIR X-ray 3.30 X 1-96 [» ]
    3KIT X-ray 3.30 X 1-96 [» ]
    3KIW X-ray 3.60 X 1-96 [» ]
    3KIY X-ray 3.60 X 1-96 [» ]
    3KNI X-ray 3.00 X 1-96 [» ]
    3KNK X-ray 3.00 X 1-96 [» ]
    3KNM X-ray 3.45 X 1-96 [» ]
    3KNO X-ray 3.45 X 1-96 [» ]
    3TVE X-ray 3.10 T 3-94 [» ]
    3TVH X-ray 3.10 T 3-94 [» ]
    3UXQ X-ray 3.20 X 1-96 [» ]
    3UXR X-ray 3.20 X 1-96 [» ]
    3UYE X-ray 3.00 T 1-96 [» ]
    3UYG X-ray 3.00 T 1-96 [» ]
    3UZ1 X-ray 3.30 T 1-96 [» ]
    3UZ2 X-ray 3.30 T 1-96 [» ]
    3UZ8 X-ray 3.00 T 1-96 [» ]
    3UZ9 X-ray 3.00 T 1-96 [» ]
    3UZF X-ray 3.30 T 1-96 [» ]
    3UZH X-ray 3.30 T 1-96 [» ]
    3UZK X-ray 3.30 T 1-96 [» ]
    3UZN X-ray 3.30 T 1-96 [» ]
    3V23 X-ray 3.00 X 1-96 [» ]
    3V25 X-ray 3.00 X 1-96 [» ]
    3V27 X-ray 3.10 X 1-96 [» ]
    3V29 X-ray 3.10 X 1-96 [» ]
    3V2D X-ray 2.70 X 1-96 [» ]
    3V2F X-ray 2.70 X 1-96 [» ]
    3V6W X-ray 3.90 X 1-96 [» ]
    3V6X X-ray 3.90 X 1-96 [» ]
    3ZN9 X-ray 3.10 X 1-96 [» ]
    3ZNE X-ray 3.10 X 1-96 [» ]
    3ZVP X-ray 3.80 X 1-96 [» ]
    4ABS X-ray 3.10 X 1-96 [» ]
    4B8G X-ray 3.70 X 1-96 [» ]
    4B8I X-ray 3.70 X 1-96 [» ]
    4BTD X-ray 2.95 X 2-96 [» ]
    4BYC X-ray 3.35 X 1-96 [» ]
    4BYE X-ray 3.35 X 1-96 [» ]
    4DHA X-ray 3.20 X 1-96 [» ]
    4DHC X-ray 3.20 X 1-96 [» ]
    4EJB X-ray 3.52 X 1-96 [» ]
    4EJC X-ray 3.52 X 1-96 [» ]
    4G5L X-ray 3.30 T 1-96 [» ]
    4G5N X-ray 3.30 T 1-96 [» ]
    4G5U X-ray 3.10 T 1-96 [» ]
    4G5W X-ray 3.10 T 1-96 [» ]
    4JUX X-ray 2.86 X 1-96 [» ]
    4K0M X-ray 3.30 X 3-94 [» ]
    4K0Q X-ray 3.30 X 3-94 [» ]
    4NVV X-ray 3.00 X 1-96 [» ]
    4NVX X-ray 3.00 X 1-96 [» ]
    4NVZ X-ray 3.10 X 1-96 [» ]
    4NW1 X-ray 3.10 X 1-96 [» ]
    ProteinModelPortali Q5SHP0.
    SMRi Q5SHP0. Positions 1-96.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 300852.TTHA1690.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAD71513 ; BAD71513 ; BAD71513 .
    GeneIDi 3168722.
    KEGGi ttj:TTHA1690.
    PATRICi 23958335. VBITheThe93045_1660.

    Phylogenomic databases

    eggNOGi COG0089.
    HOGENOMi HOG000231366.
    KOi K02892.
    OMAi TAGMMND.
    OrthoDBi EOG6HTP4P.
    PhylomeDBi Q5SHP0.

    Enzyme and pathway databases

    BioCyci TTHE300852:GH8R-1729-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q5SHP0.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    HAMAPi MF_01369_B. Ribosomal_L23_B.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR013025. Ribosomal_L25/23.
    [Graphical view ]
    Pfami PF00276. Ribosomal_L23. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54189. SSF54189. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Thermus thermophilus HB8."
      Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HB8 / ATCC 27634 / DSM 579.
    2. "Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus."
      Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T.
      Biol. Chem. 381:1079-1087(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE OF 1-23.
    3. "Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
      Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
      Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: MASS SPECTROMETRY.
    4. "The path of messenger RNA through the ribosome."
      Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
      Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
    5. Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.

    Entry informationi

    Entry nameiRL23_THET8
    AccessioniPrimary (citable) accession number: Q5SHP0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 29, 2005
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3