Q5SFD1 (Q5SFD1_STRBI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative 3-epimerase in D-allose pathway EMBL AAS79451.1

Gene names

Name:

chmJ EMBL AAS79451.1

Organism

Streptomyces bikiniensis EMBL AAS79451.1

Taxonomic identifier

1896 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4HMZ PDB 4HN0 PDB 4HN1
Gene Ontology (GO)
Biological_process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	dTDP-4-dehydrorhamnose 3,5-epimerase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SFD1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 26C8CD880701F1CA	FASTA	196	21,683
	10 20 30 40 50 60 MHPLSIEGAW SQEPVIHSDH RGRSHEWFRG ESFRQAFGHD FPVAQVNVAV SHRGALRGIH 70 80 90 100 110 120 YTEIPPGQAK YSVCVRGAGL DVVVDVRIGS PTFGRWEIVP MDAERNTAVY LTAGLGRAFL 130 140 150 160 170 180 SLTDDATLVY LCSSGYAPAR EHSVNPLDPD LGIAWPDDIE PLLSDRDENA PTLATAERLG 190 LLPTYQAWQE QQQAQR

References

[1]

"Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae." Ward S.L., Hu Z., Schirmer A., Reid R., Revill W.P., Reeves C.D., Petrakovsky O.V., Dong S.D., Katz L. Antimicrob. Agents Chemother. 48:4703-4712(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NRRL 2737 EMBL AAS79451.1.

[2]

"Structural and functional studies on a 3'-epimerase involved in the biosynthesis of dTDP-6-deoxy-D-allose." Kubiak R.L., Phillips R.K., Zmudka M.W., Ahn M.R., Maka E.M., Pyeatt G.L., Roggensack S.J., Holden H.M. Biochemistry 51:9375-9383(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY509120 Genomic DNA. Translation: AAS79451.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4HMZ	X-ray	2.00	A/B/C/D	1-196	[»]
4HN0	X-ray	2.20	A/B/C/D	1-196	[»]
4HN1	X-ray	1.60	A/B/C/D	1-196	[»]

ProteinModelPortal

Q5SFD1.

SMR

Q5SFD1. Positions 2-189.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.60.120.10. 1 hit.

InterPro

IPR000888. dTDP_sugar_isom.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]

PANTHER

PTHR21047. PTHR21047. 1 hit.

Pfam

PF00908. dTDP_sugar_isom. 1 hit.
[Graphical view]

ProDom

PD001462. dTDP_sugar_isom. 1 hit.
[Graphical view] [Entries sharing at least one domain]

SUPFAM

SSF51182. RmlC_like_cupin. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q5SFD1_STRBI

Accession

Primary (citable) accession number: Q5SFD1

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)