Q5S1W7 (Q5S1W7_XENLA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Major prion protein RuleBase RU003882
Organism	Xenopus laevis (African clawed frog) EMBL AAV54126.1
Taxonomic identifier	8355 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	171 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the prion family. RuleBase RU003882

Ontologies

Keywords
Cellular component	Amyloid Cell membrane RuleBase RU003882 Membrane
Molecular function	Prion RuleBase RU003882 EMBL AAV54126.1
Technical term	3D-structure PDB 1XU0
Gene Ontology (GO)
Biological process	protein homooligomerization Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAV54126.1
	Non-terminal residue	171	1	EMBL AAV54126.1

Sequences

	Sequence		Length	Mass (Da)
	Q5S1W7 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: AB581613644F2406	FASTA	171	19,241
	10 20 30 40 50 60 KKSGGGKSKT GGWNTGSNRN PNYPGGYPGN TGGSWGQQPY NPSGYNKQWK PPKSKTNMKS 70 80 90 100 110 120 VAIGAAAGAI GGYMLGNAVG RMSYQFNNPM ESRYYNDYYN QMPNRVYRPM YRGEEYVSED 130 140 150 160 170 RFVRDCYNMS VTEYIIKPAE GKNNSELNQL DTTVKSQIIR EMCITEYRRG S

References

[1]	Perez D.R., Wuthrich K. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Prion protein NMR structures of chickens, turtles, and frogs." Calzolai L., Lysek D.A., Perez D.R., Guentert P., Wuethrich K. Proc. Natl. Acad. Sci. U.S.A. 102:651-655(2005) [PubMed: 15647366] [Abstract] Cited for: STRUCTURE BY NMR OF 43-171.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY788895 mRNA. Translation: AAV54126.1.

UniGene

Xl.34455.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1XU0	NMR	-	A	43-171	[»]

ProteinModelPortal

Q5S1W7.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOVERGEN

HBG008260.

Family and domain databases

InterPro

IPR000817. Prion.
IPR022416. Prion/Doppel_prot_b-ribbon_dom.
[Graphical view]

Gene3D

G3DSA:1.10.790.10. Prion. 1 hit.

PANTHER

PTHR11522. Prion. 1 hit.

Pfam

PF00377. Prion. 1 hit.
[Graphical view]

SUPFAM

SSF54098. Prion. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q5S1W7_XENLA

Accession

Primary (citable) accession number: Q5S1W7

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	March 8, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)