Major prion protein - Xenopus laevis (African clawed frog)

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Unreviewed, UniProtKB/TrEMBL Q5S1W7 (Q5S1W7_XENLA)

Last modified February 9, 2010. Version 30. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names	Recommended name: Major prion protein RuleBase RU003882V4
Organism	Xenopus laevis (African clawed frog) EMBL AAV54126.1
Taxonomic identifier	8355 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	171 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the prion family.

Ontologies

Keywords
Cellular component	Amyloid Cell membrane RuleBase RU003882V4 Spearmint SPM000817 Membrane
Molecular function	Prion RuleBase RU003882V4 EMBL AAV54126.1
Gene Ontology (GO)
Biological process	protein homooligomerization Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL AAV54126.1

Non-terminal residue

1

EMBL AAV54126.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q5S1W7-1 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: AB581613644F2406
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171

19,241

        10         20         30         40         50         60 
KKSGGGKSKT GGWNTGSNRN PNYPGGYPGN TGGSWGQQPY NPSGYNKQWK PPKSKTNMKS 

        70         80         90        100        110        120 
VAIGAAAGAI GGYMLGNAVG RMSYQFNNPM ESRYYNDYYN QMPNRVYRPM YRGEEYVSED 

       130        140        150        160        170 
RFVRDCYNMS VTEYIIKPAE GKNNSELNQL DTTVKSQIIR EMCITEYRRG S

References

[1]	Perez D.R., Wuthrich K. Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Prion protein NMR structures of chickens, turtles, and frogs." Calzolai L., Lysek D.A., Perez D.R., Guentert P., Wuethrich K. Proc. Natl. Acad. Sci. U.S.A. 102:651-655(2005) [PubMed: 15647366] [Abstract] Cited for: STRUCTURE BY NMR OF 43-171.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY788895 mRNA. Translation: AAV54126.1.

UniGene

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1XU0	NMR	-	A	43-171	[»]

ModBase

Phylogenomic databases

HOVERGEN

Family and domain databases

InterPro

IPR000817. Prion.
[Graphical view]

Gene3D

G3DSA:1.10.790.10. Prion. 1 hit.

PANTHER

PTHR11522. Prion. 1 hit.

Pfam

PF00377. Prion. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

Q5S1W7_XENLA

Accession

Primary (citable) accession number: Q5S1W7

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	February 9, 2010
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information