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Protein
Submitted name:

Insulin-like 3

Gene

Insl3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-418555. G alpha (s) signalling events.
R-MMU-444821. Relaxin receptors.

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like 3Imported
Submitted name:
MCG10367, isoform CRA_aImported
Gene namesi
Name:Insl3Imported
ORF Names:mCG_10367Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:108427. Insl3.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000079019.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034261.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini26 – 12095IlGFInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410J0IS. Eukaryota.
ENOG411140J. LUCA.
GeneTreeiENSGT00510000050366.
HOVERGENiHBG052133.
KOiK05255.
OMAiPARHCCL.
OrthoDBiEOG091G128J.
TreeFamiTF106361.

Family and domain databases

Gene3Di1.10.100.10. 2 hits.
InterProiIPR016179. Insulin-like.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 2 hits.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5RL10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAPLLLMLL ALGSALRSPQ PPEARAKLCG HHLVRTLVRV CGGPRWSPEA
60 70 80 90 100
TQPVETRDRE LLQWLEQRHL LHALVADVDP ALDPQLPLQA SQRQRRSAAT
110 120
NAVHRCCLTG CTQQDLLGLC PH
Length:122
Mass (Da):13,543
Last modified:December 21, 2004 - v1
Checksum:i107828A7A84CF103
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC162033 Genomic DNA. No translation available.
BC049540 mRNA. Translation: AAH49540.1.
AK132857 mRNA. Translation: BAE21395.1.
CH466569 Genomic DNA. Translation: EDL28953.1.
RefSeqiNP_038592.3. NM_013564.7.
UniGeneiMm.476857.

Genome annotation databases

EnsembliENSMUST00000034261; ENSMUSP00000034261; ENSMUSG00000079019.
GeneIDi16336.
KEGGimmu:16336.
UCSCiuc009meq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC162033 Genomic DNA. No translation available.
BC049540 mRNA. Translation: AAH49540.1.
AK132857 mRNA. Translation: BAE21395.1.
CH466569 Genomic DNA. Translation: EDL28953.1.
RefSeqiNP_038592.3. NM_013564.7.
UniGeneiMm.476857.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034261.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000034261; ENSMUSP00000034261; ENSMUSG00000079019.
GeneIDi16336.
KEGGimmu:16336.
UCSCiuc009meq.2. mouse.

Organism-specific databases

CTDi3640.
MGIiMGI:108427. Insl3.

Phylogenomic databases

eggNOGiENOG410J0IS. Eukaryota.
ENOG411140J. LUCA.
GeneTreeiENSGT00510000050366.
HOVERGENiHBG052133.
KOiK05255.
OMAiPARHCCL.
OrthoDBiEOG091G128J.
TreeFamiTF106361.

Enzyme and pathway databases

ReactomeiR-MMU-418555. G alpha (s) signalling events.
R-MMU-444821. Relaxin receptors.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000079019.

Family and domain databases

Gene3Di1.10.100.10. 2 hits.
InterProiIPR016179. Insulin-like.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 2 hits.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5RL10_MOUSE
AccessioniPrimary (citable) accession number: Q5RL10
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 7, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.