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Protein

Solute carrier family 35 member E4

Gene

Slc35e4

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Putative transporter.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 35 member E4
Gene namesi
Name:Slc35e4
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 14

Organism-specific databases

RGDi708484. Slc35e4.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6021HelicalSequence analysisAdd
BLAST
Transmembranei79 – 9921HelicalSequence analysisAdd
BLAST
Transmembranei110 – 13021HelicalSequence analysisAdd
BLAST
Transmembranei135 – 15521HelicalSequence analysisAdd
BLAST
Transmembranei218 – 23821HelicalSequence analysisAdd
BLAST
Transmembranei258 – 27821HelicalSequence analysisAdd
BLAST
Transmembranei279 – 29921HelicalSequence analysisAdd
BLAST
Transmembranei301 – 32121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 350350Solute carrier family 35 member E4PRO_0000298929Add
BLAST

Proteomic databases

PaxDbiQ5RKL7.
PRIDEiQ5RKL7.

Expressioni

Gene expression databases

ExpressionAtlasiQ5RKL7. baseline and differential.
GenevisibleiQ5RKL7. RN.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini125 – 17955EamAAdd
BLAST

Sequence similaritiesi

Contains 1 EamA domain.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1441. Eukaryota.
ENOG410XP1S. LUCA.
GeneTreeiENSGT00730000111291.
HOGENOMiHOG000137347.
HOVERGENiHBG095658.
InParanoidiQ5RKL7.
KOiK15286.
OMAiKSVQQSA.
OrthoDBiEOG7XWPP4.
PhylomeDBiQ5RKL7.
TreeFamiTF328788.

Family and domain databases

InterProiIPR004853. Sugar_P_trans_dom.
[Graphical view]
PfamiPF03151. TPT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5RKL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCRCPLEHHE VRMTSAEAIA VAGSAQEHGR PKWPPDKPQV LGQPALARVV
60 70 80 90 100
VAALVWLLAG ASMSSLNKWI FTVHGFGRPL LLSALHMLAA AVACHWGAQR
110 120 130 140 150
PVPHSIHRRV LLLSLTFGTS MACGNVGLST VPLDLAQLAT TTTPLFTLAL
160 170 180 190 200
SALLLGRRHH PLQFAAMGPL CLGAACSLAG ELRAPPAGCG FLLVATCLRG
210 220 230 240 250
FKSVQQSALL QEERLDAVTL LYATSLPSFC LLAGAALVLE AGAAPPLPPT
260 270 280 290 300
DSRLWACVLL SCFLSVVYNL ASFSLLALTS ALTVHVLGNL TVVGNLILSR
310 320 330 340 350
LLFGSHLSAL SYVGIALTLS GMFLYHNCES VASWATRRGL WNRDQPGKGL
Length:350
Mass (Da):37,041
Last modified:December 21, 2004 - v1
Checksum:i5905059BD4D90402
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085693 mRNA. Translation: AAH85693.1.
RefSeqiNP_695228.2. NM_153316.2.
UniGeneiRn.15189.

Genome annotation databases

EnsembliENSRNOT00000005646; ENSRNOP00000005646; ENSRNOG00000004168.
GeneIDi266687.
KEGGirno:266687.
UCSCiRGD:708484. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC085693 mRNA. Translation: AAH85693.1.
RefSeqiNP_695228.2. NM_153316.2.
UniGeneiRn.15189.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ5RKL7.
PRIDEiQ5RKL7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000005646; ENSRNOP00000005646; ENSRNOG00000004168.
GeneIDi266687.
KEGGirno:266687.
UCSCiRGD:708484. rat.

Organism-specific databases

CTDi339665.
RGDi708484. Slc35e4.

Phylogenomic databases

eggNOGiKOG1441. Eukaryota.
ENOG410XP1S. LUCA.
GeneTreeiENSGT00730000111291.
HOGENOMiHOG000137347.
HOVERGENiHBG095658.
InParanoidiQ5RKL7.
KOiK15286.
OMAiKSVQQSA.
OrthoDBiEOG7XWPP4.
PhylomeDBiQ5RKL7.
TreeFamiTF328788.

Miscellaneous databases

NextBioi624496.
PROiQ5RKL7.

Gene expression databases

ExpressionAtlasiQ5RKL7. baseline and differential.
GenevisibleiQ5RKL7. RN.

Family and domain databases

InterProiIPR004853. Sugar_P_trans_dom.
[Graphical view]
PfamiPF03151. TPT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.

Entry informationi

Entry nameiS35E4_RAT
AccessioniPrimary (citable) accession number: Q5RKL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: December 21, 2004
Last modified: February 17, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.