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Q5RKI7

- S7A13_RAT

UniProt

Q5RKI7 - S7A13_RAT

Protein

Solute carrier family 7 member 13

Gene

Slc7a13

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Functioni

    Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.By similarity

    GO - Molecular functioni

    1. amino acid transmembrane transporter activity Source: InterPro

    Keywords - Biological processi

    Amino-acid transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Solute carrier family 7 member 13
    Alternative name(s):
    Sodium-independent aspartate/glutamate transporter 1
    Gene namesi
    Name:Slc7a13
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 5

    Organism-specific databases

    RGDi1311633. Slc7a13.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 479479Solute carrier family 7 member 13PRO_0000330727Add
    BLAST

    Proteomic databases

    PRIDEiQ5RKI7.

    PTM databases

    PhosphoSiteiQ5RKI7.

    Expressioni

    Gene expression databases

    GenevestigatoriQ5RKI7.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000032751.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5RKI7.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 1414CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini36 – 4712ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini69 – 8921CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini111 – 12919ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini151 – 16515CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini187 – 20822ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini230 – 24213CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini264 – 28926ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini311 – 33828CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini360 – 3601ExtracellularSequence Analysis
    Topological domaini382 – 39615CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini418 – 4236ExtracellularSequence Analysis
    Topological domaini445 – 47935CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei15 – 3521Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei48 – 6821Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei90 – 11021Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei130 – 15021Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei166 – 18621Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei209 – 22921Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei243 – 26321Helical; Name=7Sequence AnalysisAdd
    BLAST
    Transmembranei290 – 31021Helical; Name=8Sequence AnalysisAdd
    BLAST
    Transmembranei339 – 35921Helical; Name=9Sequence AnalysisAdd
    BLAST
    Transmembranei361 – 38121Helical; Name=10Sequence AnalysisAdd
    BLAST
    Transmembranei397 – 41721Helical; Name=11Sequence AnalysisAdd
    BLAST
    Transmembranei424 – 44421Helical; Name=12Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0531.
    GeneTreeiENSGT00730000110456.
    HOGENOMiHOG000098892.
    HOVERGENiHBG000476.
    InParanoidiQ5RKI7.
    KOiK13870.
    OMAiKCLALAM.
    OrthoDBiEOG7Z3F48.
    PhylomeDBiQ5RKI7.
    TreeFamiTF313355.

    Family and domain databases

    InterProiIPR002293. AA/rel_permease1.
    [Graphical view]
    PANTHERiPTHR11785. PTHR11785. 1 hit.
    PfamiPF13520. AA_permease_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006060. AA_transporter. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5RKI7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAMDIEKKIY LKRQLGYFWG TNFLIINIIG AGIFVSPKGV LQYSSMNVGV    50
    SLCVWVFCAV LSMTSTLCAA EIGITFPYTV AHYYFLKRCF GPFVAFLRLW 100
    TSLFTGPGVL ASQALLLAEY GIQPFYPSCS APAVPKKCLA LAMLWIVGIL 150
    NSRGVKELSW LQTVSMVLKM GILSFISLSG LFLLVTGRKE NVRRLQNAFD 200
    AEFPEVSRLI EAIFQGYFAF SGGGSFTYVA GELKEPSKTI PRCIFTALPL 250
    VTVVYLLANL SYLTVLSPQE LLSSDAVALT WTDRVIPQLT WSVPFAISAS 300
    LFSNLVTSVF ETSRTSYIAS RNGQLPLLCS TLNVHSSPFI AVLLDVSMGS 350
    IAIVLTNLIE LINYLFFVFS IWTVLSVIGI LKLRYQEPNL HRPYKVFSPF 400
    LFITAAISLS MVLIPLIKSP KMQYIYVFLF FLGGLLFYVP LIHFKLKLIW 450
    FQKLTCYLQL LFNICIPDVS DEHVAEEES 479
    Length:479
    Mass (Da):53,551
    Last modified:December 21, 2004 - v1
    Checksum:i9EDA418E533B2B96
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC085796 mRNA. Translation: AAH85796.1.
    RefSeqiNP_001012100.1. NM_001012100.1.
    UniGeneiRn.22708.

    Genome annotation databases

    EnsembliENSRNOT00000035685; ENSRNOP00000032751; ENSRNOG00000024903.
    GeneIDi313089.
    KEGGirno:313089.
    UCSCiRGD:1311633. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC085796 mRNA. Translation: AAH85796.1 .
    RefSeqi NP_001012100.1. NM_001012100.1.
    UniGenei Rn.22708.

    3D structure databases

    ProteinModelPortali Q5RKI7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000032751.

    PTM databases

    PhosphoSitei Q5RKI7.

    Proteomic databases

    PRIDEi Q5RKI7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000035685 ; ENSRNOP00000032751 ; ENSRNOG00000024903 .
    GeneIDi 313089.
    KEGGi rno:313089.
    UCSCi RGD:1311633. rat.

    Organism-specific databases

    CTDi 157724.
    RGDi 1311633. Slc7a13.

    Phylogenomic databases

    eggNOGi COG0531.
    GeneTreei ENSGT00730000110456.
    HOGENOMi HOG000098892.
    HOVERGENi HBG000476.
    InParanoidi Q5RKI7.
    KOi K13870.
    OMAi KCLALAM.
    OrthoDBi EOG7Z3F48.
    PhylomeDBi Q5RKI7.
    TreeFami TF313355.

    Miscellaneous databases

    NextBioi 665628.
    PROi Q5RKI7.

    Gene expression databases

    Genevestigatori Q5RKI7.

    Family and domain databases

    InterProi IPR002293. AA/rel_permease1.
    [Graphical view ]
    PANTHERi PTHR11785. PTHR11785. 1 hit.
    Pfami PF13520. AA_permease_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006060. AA_transporter. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Kidney.

    Entry informationi

    Entry nameiS7A13_RAT
    AccessioniPrimary (citable) accession number: Q5RKI7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 29, 2008
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3