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Q5RKI7

- S7A13_RAT

UniProt

Q5RKI7 - S7A13_RAT

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Protein
Solute carrier family 7 member 13
Gene
Slc7a13
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner By similarity.

GO - Molecular functioni

  1. amino acid transmembrane transporter activity Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 7 member 13
Alternative name(s):
Sodium-independent aspartate/glutamate transporter 1
Gene namesi
Name:Slc7a13
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 5

Organism-specific databases

RGDi1311633. Slc7a13.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1414Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei15 – 3521Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini36 – 4712Extracellular Reviewed prediction
Add
BLAST
Transmembranei48 – 6821Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini69 – 8921Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei90 – 11021Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini111 – 12919Extracellular Reviewed prediction
Add
BLAST
Transmembranei130 – 15021Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini151 – 16515Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei166 – 18621Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini187 – 20822Extracellular Reviewed prediction
Add
BLAST
Transmembranei209 – 22921Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini230 – 24213Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei243 – 26321Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini264 – 28926Extracellular Reviewed prediction
Add
BLAST
Transmembranei290 – 31021Helical; Name=8; Reviewed prediction
Add
BLAST
Topological domaini311 – 33828Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei339 – 35921Helical; Name=9; Reviewed prediction
Add
BLAST
Topological domaini360 – 3601Extracellular Reviewed prediction
Transmembranei361 – 38121Helical; Name=10; Reviewed prediction
Add
BLAST
Topological domaini382 – 39615Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei397 – 41721Helical; Name=11; Reviewed prediction
Add
BLAST
Topological domaini418 – 4236Extracellular Reviewed prediction
Transmembranei424 – 44421Helical; Name=12; Reviewed prediction
Add
BLAST
Topological domaini445 – 47935Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 479479Solute carrier family 7 member 13
PRO_0000330727Add
BLAST

Proteomic databases

PRIDEiQ5RKI7.

PTM databases

PhosphoSiteiQ5RKI7.

Expressioni

Gene expression databases

GenevestigatoriQ5RKI7.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000032751.

Structurei

3D structure databases

ProteinModelPortaliQ5RKI7.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0531.
GeneTreeiENSGT00730000110456.
HOGENOMiHOG000098892.
HOVERGENiHBG000476.
InParanoidiQ5RKI7.
KOiK13870.
OMAiKCLALAM.
OrthoDBiEOG7Z3F48.
PhylomeDBiQ5RKI7.
TreeFamiTF313355.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5RKI7-1 [UniParc]FASTAAdd to Basket

« Hide

MAMDIEKKIY LKRQLGYFWG TNFLIINIIG AGIFVSPKGV LQYSSMNVGV    50
SLCVWVFCAV LSMTSTLCAA EIGITFPYTV AHYYFLKRCF GPFVAFLRLW 100
TSLFTGPGVL ASQALLLAEY GIQPFYPSCS APAVPKKCLA LAMLWIVGIL 150
NSRGVKELSW LQTVSMVLKM GILSFISLSG LFLLVTGRKE NVRRLQNAFD 200
AEFPEVSRLI EAIFQGYFAF SGGGSFTYVA GELKEPSKTI PRCIFTALPL 250
VTVVYLLANL SYLTVLSPQE LLSSDAVALT WTDRVIPQLT WSVPFAISAS 300
LFSNLVTSVF ETSRTSYIAS RNGQLPLLCS TLNVHSSPFI AVLLDVSMGS 350
IAIVLTNLIE LINYLFFVFS IWTVLSVIGI LKLRYQEPNL HRPYKVFSPF 400
LFITAAISLS MVLIPLIKSP KMQYIYVFLF FLGGLLFYVP LIHFKLKLIW 450
FQKLTCYLQL LFNICIPDVS DEHVAEEES 479
Length:479
Mass (Da):53,551
Last modified:December 21, 2004 - v1
Checksum:i9EDA418E533B2B96
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC085796 mRNA. Translation: AAH85796.1.
RefSeqiNP_001012100.1. NM_001012100.1.
UniGeneiRn.22708.

Genome annotation databases

EnsembliENSRNOT00000035685; ENSRNOP00000032751; ENSRNOG00000024903.
GeneIDi313089.
KEGGirno:313089.
UCSCiRGD:1311633. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC085796 mRNA. Translation: AAH85796.1 .
RefSeqi NP_001012100.1. NM_001012100.1.
UniGenei Rn.22708.

3D structure databases

ProteinModelPortali Q5RKI7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000032751.

PTM databases

PhosphoSitei Q5RKI7.

Proteomic databases

PRIDEi Q5RKI7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000035685 ; ENSRNOP00000032751 ; ENSRNOG00000024903 .
GeneIDi 313089.
KEGGi rno:313089.
UCSCi RGD:1311633. rat.

Organism-specific databases

CTDi 157724.
RGDi 1311633. Slc7a13.

Phylogenomic databases

eggNOGi COG0531.
GeneTreei ENSGT00730000110456.
HOGENOMi HOG000098892.
HOVERGENi HBG000476.
InParanoidi Q5RKI7.
KOi K13870.
OMAi KCLALAM.
OrthoDBi EOG7Z3F48.
PhylomeDBi Q5RKI7.
TreeFami TF313355.

Miscellaneous databases

NextBioi 665628.
PROi Q5RKI7.

Gene expression databases

Genevestigatori Q5RKI7.

Family and domain databases

InterProi IPR002293. AA/rel_permease1.
[Graphical view ]
PANTHERi PTHR11785. PTHR11785. 1 hit.
Pfami PF13520. AA_permease_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006060. AA_transporter. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.

Entry informationi

Entry nameiS7A13_RAT
AccessioniPrimary (citable) accession number: Q5RKI7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 21, 2004
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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