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Protein

Protein ABHD1

Gene

Abhd1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei211 – 2111Charge relay systemBy similarity
Active sitei337 – 3371Charge relay systemBy similarity
Active sitei366 – 3661Charge relay systemBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Protein family/group databases

ESTHERiratno-abhd1. abh_upf0017.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein ABHD1Curated (EC:3.1.1.-)
Alternative name(s):
Alpha/beta hydrolase domain-containing protein 1Curated
Short name:
Abhydrolase domain-containing protein 1Imported
Gene namesi
Name:Abhd1Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi1310988. Abhd1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei24 – 4421Helical; Signal-anchor for type II membrane proteinSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 412412Protein ABHD1PRO_0000280206Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi18 – 181N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ5RK23.
PRIDEiQ5RK23.

PTM databases

PhosphoSiteiQ5RK23.

Expressioni

Gene expression databases

GenevisibleiQ5RK23. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009339.

Structurei

3D structure databases

ProteinModelPortaliQ5RK23.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1838. Eukaryota.
COG0429. LUCA.
GeneTreeiENSGT00530000062981.
HOGENOMiHOG000230596.
HOVERGENiHBG053994.
InParanoidiQ5RK23.
KOiK13696.
OMAiWYISAVP.
OrthoDBiEOG70PBXF.
PhylomeDBiQ5RK23.
TreeFamiTF313195.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR012020. ABHD4.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005211. Ab_hydro_YheT. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5RK23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYLHITKML SSSLSPQNGT WSDAISLLLA LGIALYLGYY WACVPQRPRL
60 70 80 90 100
VAGPQFLAFL EQHCPVTVET FYPTLWCFEG RLQTIFRVLL QSQPVIPYRS
110 120 130 140 150
EVLQTPDGGQ FLLDWAEQPY SSHCPDPTTQ PIVLLLPGIS GSSQEPYILH
160 170 180 190 200
LVDQALKDGY RAVVFNNRGC RGEELLTHRA YCASNTEDLE TVVKHIKHRY
210 220 230 240 250
SRAPLLAVGI SFGGILVLNY LARTGKAGGL VAGLTMSACW DSFETVDSLE
260 270 280 290 300
TPLNSLLFNQ PLTAGLCRLV ARNRKSIEKV LDVDFAIKAR TIRQLDERYT
310 320 330 340 350
SVAFGYKDCA AYYHASSPRT KVDAICTPVL CLNAADDPFS PVQALPLQAA
360 370 380 390 400
QKSPYVALLI TARGGHIGFL EGLLPWQHCY MNRVLHQYAR AVFQHSVGLP
410
GLGALTPEDG KS
Length:412
Mass (Da):45,557
Last modified:December 21, 2004 - v1
Checksum:iBA73008A6198E82B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086351 mRNA. Translation: AAH86351.1.
RefSeqiNP_001008520.1. NM_001008520.1.
UniGeneiRn.162847.

Genome annotation databases

EnsembliENSRNOT00000010403; ENSRNOP00000009339; ENSRNOG00000025689.
GeneIDi313917.
KEGGirno:313917.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086351 mRNA. Translation: AAH86351.1.
RefSeqiNP_001008520.1. NM_001008520.1.
UniGeneiRn.162847.

3D structure databases

ProteinModelPortaliQ5RK23.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009339.

Protein family/group databases

ESTHERiratno-abhd1. abh_upf0017.

PTM databases

PhosphoSiteiQ5RK23.

Proteomic databases

PaxDbiQ5RK23.
PRIDEiQ5RK23.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010403; ENSRNOP00000009339; ENSRNOG00000025689.
GeneIDi313917.
KEGGirno:313917.

Organism-specific databases

CTDi84696.
RGDi1310988. Abhd1.

Phylogenomic databases

eggNOGiKOG1838. Eukaryota.
COG0429. LUCA.
GeneTreeiENSGT00530000062981.
HOGENOMiHOG000230596.
HOVERGENiHBG053994.
InParanoidiQ5RK23.
KOiK13696.
OMAiWYISAVP.
OrthoDBiEOG70PBXF.
PhylomeDBiQ5RK23.
TreeFamiTF313195.

Miscellaneous databases

NextBioi666993.
PROiQ5RK23.

Gene expression databases

GenevisibleiQ5RK23. RN.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
IPR012020. ABHD4.
[Graphical view]
PfamiPF00561. Abhydrolase_1. 1 hit.
[Graphical view]
PIRSFiPIRSF005211. Ab_hydro_YheT. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiABHD1_RAT
AccessioniPrimary (citable) accession number: Q5RK23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 21, 2004
Last modified: April 13, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.