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Protein
Submitted name:

Igf1 protein

Gene

Igf1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Igf1 proteinImported
Submitted name:
Insulin-like growth factor 1, isoform CRA_fImported
Gene namesi
Name:Igf1Imported
ORF Names:rCG_48929Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2868. Igf1.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 127105Sequence analysisPRO_5007706485Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000004517.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000005995.

Structurei

3D structure databases

SMRiQ5RK13. Positions 23-92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 8359IlGFInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ2T. Eukaryota.
ENOG4111MIV. LUCA.
HOVERGENiHBG006137.
KOiK05459.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022341. IGF-I.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02005. INSLNLIKEGF1.
PR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5RK13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSHLFYLA LCLLTFTSSA TAGPETLCGA ELVDALQFVC GPRGFYFNKP
60 70 80 90 100
TGYGSSIRRA PQTGIVDECC FRSCDLRRLE MYCAPLKPTK SARSIRAQRH
110 120
TDMPKTQKEV HLKNTSRGSA GNKTYRM
Length:127
Mass (Da):14,106
Last modified:April 17, 2007 - v2
Checksum:i104E126BCFCA5CB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086374 mRNA. Translation: AAH86374.2.
CH473960 Genomic DNA. Translation: EDM17030.1.
RefSeqiNP_001075946.2. NM_001082477.2.
NP_001075947.1. NM_001082478.1.
NP_001075948.1. NM_001082479.1.
NP_849197.3. NM_178866.4.
UniGeneiRn.201887.
Rn.228346.
Rn.6282.

Genome annotation databases

GeneIDi24482.
KEGGirno:24482.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086374 mRNA. Translation: AAH86374.2.
CH473960 Genomic DNA. Translation: EDM17030.1.
RefSeqiNP_001075946.2. NM_001082477.2.
NP_001075947.1. NM_001082478.1.
NP_001075948.1. NM_001082479.1.
NP_849197.3. NM_178866.4.
UniGeneiRn.201887.
Rn.228346.
Rn.6282.

3D structure databases

SMRiQ5RK13. Positions 23-92.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000005995.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi24482.
KEGGirno:24482.

Organism-specific databases

CTDi3479.
RGDi2868. Igf1.

Phylogenomic databases

eggNOGiENOG410IJ2T. Eukaryota.
ENOG4111MIV. LUCA.
HOVERGENiHBG006137.
KOiK05459.

Gene expression databases

BgeeiENSRNOG00000004517.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022341. IGF-I.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF00049. Insulin. 2 hits.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02005. INSLNLIKEGF1.
PR00276. INSULINFAMLY.
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5RK13_RAT
AccessioniPrimary (citable) accession number: Q5RK13
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: April 17, 2007
Last modified: September 7, 2016
This is version 94 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.