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Protein
Submitted name:

Igf1 protein

Gene

Igf1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Igf1 proteinImported
Submitted name:
Insulin-like growth factor 1, isoform CRA_fImported
Gene namesi
Name:Igf1Imported
ORF Names:rCG_48929Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2868 Igf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501430994023 – 127Sequence analysisAdd BLAST105

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 83IlGFInterPro annotationAdd BLAST59

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ2T Eukaryota
ENOG4111MIV LUCA
HOVERGENiHBG006137
KOiK05459

Family and domain databases

InterProiView protein in InterPro
IPR022341 IGF-I
IPR016179 Insulin-like
IPR022350 Insulin-like_growth_factor
IPR036438 Insulin-like_sf
IPR022353 Insulin_CS
IPR022352 Insulin_family
PfamiView protein in Pfam
PF00049 Insulin, 2 hits
PRINTSiPR02002 INSLNLIKEGF
PR02005 INSLNLIKEGF1
PR00276 INSULINFAMLY
SMARTiView protein in SMART
SM00078 IlGF, 1 hit
SUPFAMiSSF56994 SSF56994, 1 hit
PROSITEiView protein in PROSITE
PS00262 INSULIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q5RK13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSHLFYLA LCLLTFTSSA TAGPETLCGA ELVDALQFVC GPRGFYFNKP
60 70 80 90 100
TGYGSSIRRA PQTGIVDECC FRSCDLRRLE MYCAPLKPTK SARSIRAQRH
110 120
TDMPKTQKEV HLKNTSRGSA GNKTYRM
Length:127
Mass (Da):14,106
Last modified:April 17, 2007 - v2
Checksum:i104E126BCFCA5CB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086374 mRNA Translation: AAH86374.2
CH473960 Genomic DNA Translation: EDM17030.1
RefSeqiNP_001075946.2, NM_001082477.2
NP_001075947.1, NM_001082478.1
NP_001075948.1, NM_001082479.1
NP_849197.3, NM_178866.4
UniGeneiRn.201887
Rn.228346
Rn.6282

Genome annotation databases

GeneIDi24482
KEGGirno:24482

Entry informationi

Entry nameiQ5RK13_RAT
AccessioniPrimary (citable) accession number: Q5RK13
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: April 17, 2007
Last modified: April 25, 2018
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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