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Protein

39S ribosomal protein L46, mitochondrial

Gene

Mrpl46

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-5389840. Mitochondrial translation elongation.
R-RNO-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L46, mitochondrial
Short name:
L46mt
Short name:
MRP-L46
Gene namesi
Name:Mrpl46
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1309123. Mrpl46.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 27739S ribosomal protein L46, mitochondrialPRO_0000273556
Transit peptidei1 – ?MitochondrionSequence analysis

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei217 – 2171N6-succinyllysineBy similarity
Modified residuei228 – 2281N6-acetyllysineBy similarity
Modified residuei246 – 2461N6-succinyllysineBy similarity

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ5RK00.
PRIDEiQ5RK00.

Expressioni

Gene expression databases

GenevisibleiQ5RK00. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061438.

Structurei

3D structure databases

ProteinModelPortaliQ5RK00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L46 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG4548. Eukaryota.
ENOG4111HSF. LUCA.
GeneTreeiENSGT00390000015400.
HOGENOMiHOG000047532.
HOVERGENiHBG057426.
InParanoidiQ5RK00.
KOiK17427.
OMAiFHKYKYP.
OrthoDBiEOG7GN2NC.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR015797. NUDIX_hydrolase_dom-like.
IPR021757. Ribosomal_L46.
[Graphical view]
PfamiPF11788. MRP-L46. 1 hit.
[Graphical view]
SUPFAMiSSF55811. SSF55811. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5RK00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPIGRTLL GVAKGWRQLD RLWAGSSRGL SLEAAPSSSR SPWRLSGALC
60 70 80 90 100
LQRPPLITKP LTPLQEEMAG LLQQVEVERS LYSDHELRAL DEAQRLAKKK
110 120 130 140 150
ADLYDEEQDQ DVTLAQDLED MWEQEFLQFR PGARETEADK KNDRTSLHRK
160 170 180 190 200
LDRNLILLVR EKLGDQDLWM LPQVEWQPGE TLRGTAERIL ATLSENNMEA
210 220 230 240 250
KFLGNAPCGH YKFKFPKAIR TESDLGVKVF FFKALLLTGD FVQTGKKGRH
260 270
VWASKEELGD YLQPKYLAQV RRFLLDL
Length:277
Mass (Da):31,673
Last modified:December 21, 2004 - v1
Checksum:i07612893DD4D1083
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086407 mRNA. Translation: AAH86407.1.
RefSeqiNP_001013086.1. NM_001013068.1.
UniGeneiRn.104883.

Genome annotation databases

EnsembliENSRNOT00000067172; ENSRNOP00000061438; ENSRNOG00000018547.
GeneIDi293054.
KEGGirno:293054.
UCSCiRGD:1309123. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086407 mRNA. Translation: AAH86407.1.
RefSeqiNP_001013086.1. NM_001013068.1.
UniGeneiRn.104883.

3D structure databases

ProteinModelPortaliQ5RK00.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061438.

Proteomic databases

PaxDbiQ5RK00.
PRIDEiQ5RK00.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000067172; ENSRNOP00000061438; ENSRNOG00000018547.
GeneIDi293054.
KEGGirno:293054.
UCSCiRGD:1309123. rat.

Organism-specific databases

CTDi26589.
RGDi1309123. Mrpl46.

Phylogenomic databases

eggNOGiKOG4548. Eukaryota.
ENOG4111HSF. LUCA.
GeneTreeiENSGT00390000015400.
HOGENOMiHOG000047532.
HOVERGENiHBG057426.
InParanoidiQ5RK00.
KOiK17427.
OMAiFHKYKYP.
OrthoDBiEOG7GN2NC.

Enzyme and pathway databases

ReactomeiR-RNO-5389840. Mitochondrial translation elongation.
R-RNO-5419276. Mitochondrial translation termination.

Miscellaneous databases

NextBioi635269.
PROiQ5RK00.

Gene expression databases

GenevisibleiQ5RK00. RN.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR015797. NUDIX_hydrolase_dom-like.
IPR021757. Ribosomal_L46.
[Graphical view]
PfamiPF11788. MRP-L46. 1 hit.
[Graphical view]
SUPFAMiSSF55811. SSF55811. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiRM46_RAT
AccessioniPrimary (citable) accession number: Q5RK00
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: December 21, 2004
Last modified: May 11, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.