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Protein

39S ribosomal protein L46, mitochondrial

Gene

Mrpl46

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-RNO-5389840 Mitochondrial translation elongation
R-RNO-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L46, mitochondrial
Short name:
L46mt
Short name:
MRP-L46
Gene namesi
Name:Mrpl46
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1309123 Mrpl46

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000273556? – 27739S ribosomal protein L46, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei217N6-succinyllysineBy similarity1
Modified residuei228N6-acetyllysineBy similarity1
Modified residuei246N6-succinyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ5RK00
PRIDEiQ5RK00

Expressioni

Gene expression databases

BgeeiENSRNOG00000018547
GenevisibleiQ5RK00 RN

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000061438

Structurei

3D structure databases

ProteinModelPortaliQ5RK00
SMRiQ5RK00
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG4548 Eukaryota
ENOG4111HSF LUCA
GeneTreeiENSGT00390000015400
HOGENOMiHOG000047532
HOVERGENiHBG057426
InParanoidiQ5RK00
KOiK17427
OMAiEKWDLYA
OrthoDBiEOG091G0CQP

Family and domain databases

CDDicd04661 MRP_L46, 1 hit
InterProiView protein in InterPro
IPR033650 MRP_L46_NUDIX
IPR015797 NUDIX_hydrolase-like_dom_sf
IPR021757 Ribosomal_L46
PfamiView protein in Pfam
PF11788 MRP-L46, 1 hit
SUPFAMiSSF55811 SSF55811, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5RK00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAPIGRTLL GVAKGWRQLD RLWAGSSRGL SLEAAPSSSR SPWRLSGALC
60 70 80 90 100
LQRPPLITKP LTPLQEEMAG LLQQVEVERS LYSDHELRAL DEAQRLAKKK
110 120 130 140 150
ADLYDEEQDQ DVTLAQDLED MWEQEFLQFR PGARETEADK KNDRTSLHRK
160 170 180 190 200
LDRNLILLVR EKLGDQDLWM LPQVEWQPGE TLRGTAERIL ATLSENNMEA
210 220 230 240 250
KFLGNAPCGH YKFKFPKAIR TESDLGVKVF FFKALLLTGD FVQTGKKGRH
260 270
VWASKEELGD YLQPKYLAQV RRFLLDL
Length:277
Mass (Da):31,673
Last modified:December 21, 2004 - v1
Checksum:i07612893DD4D1083
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC086407 mRNA Translation: AAH86407.1
RefSeqiNP_001013086.1, NM_001013068.1
UniGeneiRn.104883

Genome annotation databases

EnsembliENSRNOT00000067172; ENSRNOP00000061438; ENSRNOG00000018547
GeneIDi293054
KEGGirno:293054
UCSCiRGD:1309123 rat

Similar proteinsi

Entry informationi

Entry nameiRM46_RAT
AccessioniPrimary (citable) accession number: Q5RK00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health