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Protein
Submitted name:

Uncharacterized protein

Gene

tprb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DRE-159236. Transport of Mature mRNA derived from an Intron-Containing Transcript.
R-DRE-170822. Regulation of Glucokinase by Glucokinase Regulatory Protein.
R-DRE-3108214. SUMOylation of DNA damage response and repair proteins.
R-DRE-3301854. Nuclear Pore Complex (NPC) Disassembly.
R-DRE-3371453. Regulation of HSF1-mediated heat shock response.
R-DRE-4570464. SUMOylation of RNA binding proteins.
R-DRE-5578749. Transcriptional regulation by small RNAs.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:tprbImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 20

Organism-specific databases

ZFINiZDB-GENE-030131-6410. tprb.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ5RI09.

Expressioni

Gene expression databases

BgeeiQ5RI09.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000019846.

Structurei

3D structure databases

ProteinModelPortaliQ5RI09.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1041 – 1168128TPR_MLP1_2InterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili22 – 4928Sequence analysisAdd
BLAST
Coiled coili75 – 17298Sequence analysisAdd
BLAST
Coiled coili219 – 28163Sequence analysisAdd
BLAST
Coiled coili293 – 36674Sequence analysisAdd
BLAST
Coiled coili429 – 51587Sequence analysisAdd
BLAST
Coiled coili546 – 57328Sequence analysisAdd
BLAST
Coiled coili579 – 60628Sequence analysisAdd
BLAST
Coiled coili695 – 76470Sequence analysisAdd
BLAST
Coiled coili772 – 80635Sequence analysisAdd
BLAST
Coiled coili832 – 87342Sequence analysisAdd
BLAST
Coiled coili882 – 91938Sequence analysisAdd
BLAST
Coiled coili929 – 97042Sequence analysisAdd
BLAST
Coiled coili982 – 1081100Sequence analysisAdd
BLAST
Coiled coili1224 – 125128Sequence analysisAdd
BLAST
Coiled coili1272 – 130635Sequence analysisAdd
BLAST
Coiled coili1314 – 134128Sequence analysisAdd
BLAST
Coiled coili1392 – 141928Sequence analysisAdd
BLAST
Coiled coili1470 – 155687Sequence analysisAdd
BLAST
Coiled coili1568 – 162760Sequence analysisAdd
BLAST
Coiled coili1952 – 199140Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4674. Eukaryota.
ENOG410XSA1. LUCA.
GeneTreeiENSGT00730000111014.
HOGENOMiHOG000139431.
HOVERGENiHBG009158.
InParanoidiQ5RI09.
KOiK09291.
OMAiESAICKL.
OrthoDBiEOG7JQBMF.
PhylomeDBiQ5RI09.
TreeFamiTF350364.

Family and domain databases

InterProiIPR012929. TPR/MLP1.
[Graphical view]
PfamiPF07926. TPR_MLP1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5RI09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAVLQQILE RSEISKLQKT VLTKLEKYIS EQQCEVDDLK AQQEQFRVDS
60 70 80 90 100
EQQYFDIEKK FAESQAQFVS QTQEHQILKE EHYKLEDELK CLRENNKEQA
110 120 130 140 150
ASYAKLESKQ NDLSKAKDEL EAEKRELVRT LERRSQEMEH QSEDLKRLND
160 170 180 190 200
RLVEVSAEKM QLQLKLEESE TSEVSIKYKE KRMEQEKDLL QSQVTWLNTE
210 220 230 240 250
LKAKSEELLS LSRQRGNEIL ELQCNLNNKE DEITRLQDQV TSLKASNETF
260 270 280 290 300
QKQAEEMIIK MREAKEQQAA LEEKFSNELN ANIKLSNLYK GAAADAEAKS
310 320 330 340 350
EELSRAVDEL HKLLKEAGEA HKDLEVKMAD LESHKNKEIA ELKEKISSQE
360 370 380 390 400
KELDNANDLL SDSRHRGAAS ILTEEQVTIM SPTAAAVAKM IKPGMKLTEI
410 420 430 440 450
YTAYVETQEH LQREKLENKR LHKYLDDIVQ EMEAKAPILK RQREEYERMQ
460 470 480 490 500
KSVSSLSAKL EQAVTEVHRL QKESDESNKR ASVLERDNQR FEVQLADMAQ
510 520 530 540 550
QVRVLLVELE EARGNHVMRE DDDVGSADVS STSEVISQHL VTFRSVEELQ
560 570 580 590 600
QQNQRLLVAL RDLSEEKEKD ELEGDTMKRS EVEKYLEELQ RELEQLKEKR
610 620 630 640 650
TQDLQKVDTV ARQRDMFRML LTQTTGVTFP QGAGAEELML TSTPRRSPAV
660 670 680 690 700
TPTTGTPTAL VATAIESTES VEAKAALKQL QEVFVAYKKE KIESEKAQIE
710 720 730 740 750
QNEKLQDQVT ELRSENMKIS TQLEFTSKRY EMLQDNVEGY RKDIASLNEK
760 770 780 790 800
LQKQAAAIQQ SEQTTHTLTQ DLQAAAEKLS IAESELENLR KERDMLKLVE
810 820 830 840 850
IRLTQEKESF QAQQLGQNML LTNLKSIQTT LERSETETRQ RLTAQIEKQE
860 870 880 890 900
REITQLQKRL ENEVEQKHLL ARNQDVQLMD TKKQLEAQIA QHHKTKEQLS
910 920 930 940 950
AAQLELTNLR LQLNSGESRL ASAAVHTGLQ GSERDMEVLR AQIRQTENRI
960 970 980 990 1000
EELTERLKNT TASMEQYKAM SLSLEESLDK EKQVTEQVRS SVENQVEAAQ
1010 1020 1030 1040 1050
EQYKRLEQKL LEMDKEKQNL LEEKNKAVAA VEQELTELRK SLSSVQAELQ
1060 1070 1080 1090 1100
SAQEKAAVAA AQEQQALLDG QEQAKMAAEA QDKYEREMLL HAADVEALQA
1110 1120 1130 1140 1150
AKAQAQQASL VRQQLEEKVQ ITSAQLLEAR VSWEEQEKIL KEEQCKIQSR
1160 1170 1180 1190 1200
CENLQRQNKL LHEQIQTLSG QMASQLKRAT TESPLNVSLT EEGKSQEQLL
1210 1220 1230 1240 1250
EILRFVRREK EIAESRFEVV QGESLRHRLR VEHLERELKD MQESLNAERE
1260 1270 1280 1290 1300
RMQVTAKTLA QHDELMKKTE TMNVLMETNK MLREEKEKLE KELQDTQAKI
1310 1320 1330 1340 1350
RKLESDIMPV QESNSELSEK SGMLQAEKKL LEEDIKRWKA RTQHLVSQQK
1360 1370 1380 1390 1400
DTDPEEYKRL HSEREAHLKR IQQLVEETGR LKADAARSSG SLTTLQSQVQ
1410 1420 1430 1440 1450
NLRENLGKVM VERDNLKKDQ EAKILDIQEK IKTITQVKKI GRRYKTQYEE
1460 1470 1480 1490 1500
LKVEYEKLVA AAASAPAQDQ EAQQASAQEL QNLKESLNQS ETRIRELEGQ
1510 1520 1530 1540 1550
LENLNRTVGE REMEARSAQE QASRLQTELT RLRQELQEKS SQEERLKQQL
1560 1570 1580 1590 1600
TEKEERTKKA ILLAKQKISQ LTGIKGQFQK ENEELKQQKE ELEVRVSALK
1610 1620 1630 1640 1650
SQYEGRLSRQ ERELRDLREQ QERHGEQRDE PQEQGSSKTQ EPQRTTEQRQ
1660 1670 1680 1690 1700
ISLKTTPAAE RGSASTSEPP TANIKPTPLA ATPSKPQVIP GNKSTPRASI
1710 1720 1730 1740 1750
KPMITPAPVP TPTPTATVMP TTQVESQEPM QSSESPLEHV TVYGSASGSV
1760 1770 1780 1790 1800
RSTSPNVQTT LAQPLLNVQQ QNQATAFIQP TQQQTQPPAE PSNQEPPAAL
1810 1820 1830 1840 1850
MLPTSQLDRP LSTSTGLWSA TPSTSSASAV SASPGSALSK RPREEEQESM
1860 1870 1880 1890 1900
SADTQSQDEP NDSPTCKRLR IHRVGLEEEM LAEDSTEAES VVPGEIQEAP
1910 1920 1930 1940 1950
DAGQELENYS TLEEMDEEPG PSQSVPGDRM LPHPSETHRS PEEPDHHVIV
1960 1970 1980 1990 2000
IVSDTESEGE QEEESEEEEE EEEEEQDYEE EDEEEEEEDD DDDEEDGGIG
2010 2020 2030 2040 2050
EEGDESNEES RDDNEAYEGD DTEGPDPTDP GTETEESLGA TDSTQRMADS
2060 2070 2080 2090 2100
QSFESNTLEM FEVPVTSSAP RPPQSPRRPQ HPLPPRLNIL AAPAQELGPP
2110 2120 2130 2140 2150
AQVQRLPARR QSVGRGLQLA SGMASSAQPF FEDDDRMVPS TPTLPLRSDG
2160 2170 2180 2190 2200
FAEAIHSPQV AGVPRFRFGL LDELPQTSSS HSDLSQLPSQ GLGMYESSVF
2210 2220 2230 2240 2250
LGSHEDESGG RSVPTTPLQI SAPVTILSEA AVSEASEHAS QSVPMVSTST
2260 2270 2280 2290 2300
PGLSAPAVEE RDDMFLDAGD SAEASLEAVS QTEAEEAAQP SDDANLPSTS
2310 2320 2330 2340 2350
QEPSSSSADT SSSQPPKARS GSGRQWTGSR GSRSIVKRDG LSVMGVRGRF

AR
Length:2,352
Mass (Da):265,981
Last modified:December 21, 2004 - v1
Checksum:iD05C4EFFE1128374
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323056 Genomic DNA. No translation available.
RefSeqiNP_001025294.1. NM_001030123.1.
UniGeneiDr.52426.

Genome annotation databases

EnsembliENSDART00000017941; ENSDARP00000019846; ENSDARG00000016630.
GeneIDi558883.
KEGGidre:558883.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323056 Genomic DNA. No translation available.
RefSeqiNP_001025294.1. NM_001030123.1.
UniGeneiDr.52426.

3D structure databases

ProteinModelPortaliQ5RI09.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000019846.

Proteomic databases

PaxDbiQ5RI09.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000017941; ENSDARP00000019846; ENSDARG00000016630.
GeneIDi558883.
KEGGidre:558883.

Organism-specific databases

CTDi558883.
ZFINiZDB-GENE-030131-6410. tprb.

Phylogenomic databases

eggNOGiKOG4674. Eukaryota.
ENOG410XSA1. LUCA.
GeneTreeiENSGT00730000111014.
HOGENOMiHOG000139431.
HOVERGENiHBG009158.
InParanoidiQ5RI09.
KOiK09291.
OMAiESAICKL.
OrthoDBiEOG7JQBMF.
PhylomeDBiQ5RI09.
TreeFamiTF350364.

Enzyme and pathway databases

ReactomeiR-DRE-159236. Transport of Mature mRNA derived from an Intron-Containing Transcript.
R-DRE-170822. Regulation of Glucokinase by Glucokinase Regulatory Protein.
R-DRE-3108214. SUMOylation of DNA damage response and repair proteins.
R-DRE-3301854. Nuclear Pore Complex (NPC) Disassembly.
R-DRE-3371453. Regulation of HSF1-mediated heat shock response.
R-DRE-4570464. SUMOylation of RNA binding proteins.
R-DRE-5578749. Transcriptional regulation by small RNAs.

Gene expression databases

BgeeiQ5RI09.

Family and domain databases

InterProiIPR012929. TPR/MLP1.
[Graphical view]
PfamiPF07926. TPR_MLP1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ5RI09_DANRE
AccessioniPrimary (citable) accession number: Q5RI09
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: June 8, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.