Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Prostaglandin G/H synthase 2b

Gene

ptgs2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

  • heme binding Source: InterPro
  • peroxidase activity Source: ZFIN
  • prostaglandin-endoperoxide synthase activity Source: InterPro

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-197264 Nicotinamide salvaging
R-DRE-2142770 Synthesis of 15-eicosatetraenoic acid derivatives
R-DRE-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX)

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin G/H synthase 2bImported
Submitted name:
Prostaglandin-endoperoxide synthase 2bImported
Gene namesi
Name:ptgs2bImported
Synonyms:si:dkey-97o5.6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 20

Organism-specific databases

ZFINiZDB-GENE-041014-323 ptgs2b

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501410584821 – 606Sequence analysisAdd BLAST586

Expressioni

Gene expression databases

BgeeiENSDARG00000010276

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000003684

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 57EGF-likeInterPro annotationAdd BLAST39

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2408 Eukaryota
ENOG410XPZ3 LUCA
GeneTreeiENSGT00390000010743
HOGENOMiHOG000013149
HOVERGENiHBG000366
KOiK11987
OMAiCNNVKGC
OrthoDBiEOG091G03CD
TreeFamiTF329675

Family and domain databases

Gene3Di1.10.640.10, 1 hit
InterProiView protein in InterPro
IPR029576 COX-2
IPR000742 EGF-like_dom
IPR010255 Haem_peroxidase
IPR019791 Haem_peroxidase_animal
IPR037120 Haem_peroxidase_sf
PANTHERiPTHR11903:SF8 PTHR11903:SF8, 1 hit
PfamiView protein in Pfam
PF03098 An_peroxidase, 1 hit
PRINTSiPR00457 ANPEROXIDASE
SUPFAMiSSF48113 SSF48113, 1 hit
PROSITEiView protein in PROSITE
PS50026 EGF_3, 1 hit
PS50292 PEROXIDASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q5RI06-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSSVLFIFL LLGFVVCTGA NPCCSHPCQN RGVCTEMGSD AYECDCTRTG
60 70 80 90 100
YYGQNCTTPE FLTWVKVSLK PSPNTVHYIL THFKSLWNII NNVSFLRNGI
110 120 130 140 150
MRYVLTSRAH LIDSPPTFNA DYGYKSWEAY SNLSYYTRTL PPVPRDCPTP
160 170 180 190 200
MGVAGKKELP DVKMLAEKLL LRRKFIPDPQ RTNLMFAFFA QHFTHQFFKS
210 220 230 240 250
DMKKGPAFTT ALNHGVDLAH IYGQNLDRQH KLRLFKDGKL RYQILDGEVY
260 270 280 290 300
PPTVSEVQVD MHYPPHVPES RRFAVGHEAF GLVPGLMMYA TIWLREHNRV
310 320 330 340 350
CDILKQEHPD WDDERLFQTS RLILIGETIK IVIEDYVQHL SGYYFKLKFD
360 370 380 390 400
PELLFNERFQ YQNRISSEFN TLYHWHPLMP DDFHIQDEVY NYQQFLFNTS
410 420 430 440 450
ILTDYGVNSL VESFNKQIAG RVAGGRNVAP AVLRVAIKSI ENSRQMRYQS
460 470 480 490 500
INAYRKRFNM KPYRSFEEMT GEKEMAAELE EMYGDVDAVE LYAGLLVEKP
510 520 530 540 550
RSNAIFGETM VEMGAPYSLK GLMGNPICSP EYWKPSTFGG KVGFEIVNSA
560 570 580 590 600
SLQNLVCNNV NGPCPMASFY VPNVKDSLPT TINASTSQSD RNVNPTVLLK

ERTSEL
Length:606
Mass (Da):69,465
Last modified:December 21, 2004 - v1
Checksum:iC0601EA49A06EA6A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323056 Genomic DNA No translation available.
BC139568 mRNA Translation: AAI39569.1
DQ494791 mRNA Translation: ABF50051.1
RefSeqiNP_001020675.1, NM_001025504.2
UniGeneiDr.48719

Genome annotation databases

EnsembliENSDART00000010028; ENSDARP00000003684; ENSDARG00000010276
GeneIDi559020
KEGGidre:559020

Similar proteinsi

Entry informationi

Entry nameiQ5RI06_DANRE
AccessioniPrimary (citable) accession number: Q5RI06
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health