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Protein
Submitted name:

Glycogen synthase 2

Gene

gys2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. glycogen (starch) synthase activity Source: UniProtKB

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB
  2. response to glucose Source: UniProtKB
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_180909. Glycogen synthesis.
REACT_203198. Myoclonic epilepsy of Lafora.

Protein family/group databases

CAZyiGT3. Glycosyltransferase Family 3.

Names & Taxonomyi

Protein namesi
Submitted name:
Glycogen synthase 2Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:gys2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 4

Organism-specific databases

ZFINiZDB-GENE-030826-31. gys2.

Subcellular locationi

GO - Cellular componenti

  1. cell cortex Source: UniProtKB
  2. cortical actin cytoskeleton Source: UniProtKB
  3. cytoplasm Source: UniProtKB
  4. cytoskeleton Source: UniProtKB
  5. cytosol Source: UniProtKB
  6. ectoplasm Source: UniProtKB
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000002983.

Structurei

3D structure databases

ProteinModelPortaliQ5RGX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0438.
GeneTreeiENSGT00390000018612.
HOGENOMiHOG000160890.
HOVERGENiHBG001960.
KOiK00693.
OMAiIMKRAIY.
OrthoDBiEOG741Z1N.
PhylomeDBiQ5RGX8.
TreeFamiTF300306.

Family and domain databases

InterProiIPR008631. Glycogen_synth.
[Graphical view]
PANTHERiPTHR10176. PTHR10176. 1 hit.
PfamiPF05693. Glycogen_syn. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5RGX8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLSRSLSIT SLSGLPLFEE ESLPVEDLLL FEVAWEVTNK VGGIYTVIQT
60 70 80 90 100
KAKITVDEWG ENYFMMGPYY EHNFKTQVEK CEPPNQAIRA AMDSLINNGC
110 120 130 140 150
QVHFGRWLIE GSPYVILFDI GAAAWNLDRW KGDLWSACGI GLPYHDREAN
160 170 180 190 200
DSLILGSLVA WFFKELTDQL QDKLNVVAHF HEWQAGTGLV LSRSRNLPLA
210 220 230 240 250
TIFTTHATLL GRYLCAGNAD FYNNLDKFDI DREAGERQIY HRYCLERAAV
260 270 280 290 300
HCAHVFTTVS QITAVEADHM LHRNPDVVTP NGLNVRKFSA MHEFQNLHSM
310 320 330 340 350
NKSKIQEFVR GHFYGHLDFN LEKTLFFFIA GRYEFSNKGA DLFLESLSRL
360 370 380 390 400
NYLLRVHKSD VTVVVFFIMP AKTNNFNVES LKGQAVRKQL WDTAQSVKEK
410 420 430 440 450
FGKKLYESLL RGEIPDMSKI LDRDDFTIMK RAIYATQRHS LPPVTTHNML
460 470 480 490 500
DDSTDPILGN IRRIGLFNGR NDRVKIVFHP EFLSSTSPLL PMDYEEFVRG
510 520 530 540 550
CHLGVFPSYY EPWGYTPGEC TVMGIPSVTT NLSGFGCFME EHVSDPSEYG
560 570 580 590 600
IYIVDRRFRS ADESCNQLTQ FMFSFCQKSR RQRIIQRNRT ERLSDLLDWR
610 620 630 640 650
YLGRFYMHAR HLALSRSFPE KFRPEHLNLT STQGFRYPRP SSVPPSPSAS
660 670 680 690 700
IHSTPHHSDE EDDDTYDEEE EAERDRLNIK APFSVGADTD GKRTQPVENG

N
Length:701
Mass (Da):80,581
Last modified:December 21, 2004 - v1
Checksum:i66B767488D5FC820
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX649476 Genomic DNA. No translation available.
BC095660 mRNA. Translation: AAH95660.1.
RefSeqiNP_001018199.1. NM_001018679.1.
UniGeneiDr.33913.

Genome annotation databases

EnsembliENSDART00000014007; ENSDARP00000002983; ENSDARG00000004904.
GeneIDi373082.
KEGGidre:373082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX649476 Genomic DNA. No translation available.
BC095660 mRNA. Translation: AAH95660.1.
RefSeqiNP_001018199.1. NM_001018679.1.
UniGeneiDr.33913.

3D structure databases

ProteinModelPortaliQ5RGX8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000002983.

Protein family/group databases

CAZyiGT3. Glycosyltransferase Family 3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000014007; ENSDARP00000002983; ENSDARG00000004904.
GeneIDi373082.
KEGGidre:373082.

Organism-specific databases

CTDi2998.
ZFINiZDB-GENE-030826-31. gys2.

Phylogenomic databases

eggNOGiCOG0438.
GeneTreeiENSGT00390000018612.
HOGENOMiHOG000160890.
HOVERGENiHBG001960.
KOiK00693.
OMAiIMKRAIY.
OrthoDBiEOG741Z1N.
PhylomeDBiQ5RGX8.
TreeFamiTF300306.

Enzyme and pathway databases

ReactomeiREACT_180909. Glycogen synthesis.
REACT_203198. Myoclonic epilepsy of Lafora.

Miscellaneous databases

NextBioi20813355.
PROiQ5RGX8.

Family and domain databases

InterProiIPR008631. Glycogen_synth.
[Graphical view]
PANTHERiPTHR10176. PTHR10176. 1 hit.
PfamiPF05693. Glycogen_syn. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: LiverImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  3. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ5RGX8_DANRE
AccessioniPrimary (citable) accession number: Q5RGX8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: February 4, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.