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Q5RGX8

- Q5RGX8_DANRE

UniProt

Q5RGX8 - Q5RGX8_DANRE

Protein
Submitted name:

Glycogen synthase 2

Gene

gys2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. glycogen (starch) synthase activity Source: UniProtKB

    GO - Biological processi

    1. glycogen biosynthetic process Source: UniProtKB
    2. response to glucose Source: UniProtKB

    Enzyme and pathway databases

    ReactomeiREACT_180909. Glycogen synthesis.
    REACT_203198. Myoclonic epilepsy of Lafora.

    Protein family/group databases

    CAZyiGT3. Glycosyltransferase Family 3.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glycogen synthase 2Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:gys2Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Chromosome 4

    Organism-specific databases

    ZFINiZDB-GENE-030826-31. gys2.

    Subcellular locationi

    GO - Cellular componenti

    1. cell cortex Source: UniProtKB
    2. cortical actin cytoskeleton Source: UniProtKB
    3. cytoplasm Source: UniProtKB
    4. cytoskeleton Source: UniProtKB
    5. cytosol Source: UniProtKB
    6. ectoplasm Source: UniProtKB

    Interactioni

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000002983.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0438.
    GeneTreeiENSGT00390000018612.
    HOGENOMiHOG000160890.
    HOVERGENiHBG001960.
    InParanoidiQ5RGX8.
    KOiK00693.
    OMAiEVSWEVT.
    OrthoDBiEOG741Z1N.
    TreeFamiTF300306.

    Family and domain databases

    InterProiIPR008631. Glycogen_synth.
    [Graphical view]
    PANTHERiPTHR10176. PTHR10176. 1 hit.
    PfamiPF05693. Glycogen_syn. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5RGX8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRLSRSLSIT SLSGLPLFEE ESLPVEDLLL FEVAWEVTNK VGGIYTVIQT    50
    KAKITVDEWG ENYFMMGPYY EHNFKTQVEK CEPPNQAIRA AMDSLINNGC 100
    QVHFGRWLIE GSPYVILFDI GAAAWNLDRW KGDLWSACGI GLPYHDREAN 150
    DSLILGSLVA WFFKELTDQL QDKLNVVAHF HEWQAGTGLV LSRSRNLPLA 200
    TIFTTHATLL GRYLCAGNAD FYNNLDKFDI DREAGERQIY HRYCLERAAV 250
    HCAHVFTTVS QITAVEADHM LHRNPDVVTP NGLNVRKFSA MHEFQNLHSM 300
    NKSKIQEFVR GHFYGHLDFN LEKTLFFFIA GRYEFSNKGA DLFLESLSRL 350
    NYLLRVHKSD VTVVVFFIMP AKTNNFNVES LKGQAVRKQL WDTAQSVKEK 400
    FGKKLYESLL RGEIPDMSKI LDRDDFTIMK RAIYATQRHS LPPVTTHNML 450
    DDSTDPILGN IRRIGLFNGR NDRVKIVFHP EFLSSTSPLL PMDYEEFVRG 500
    CHLGVFPSYY EPWGYTPGEC TVMGIPSVTT NLSGFGCFME EHVSDPSEYG 550
    IYIVDRRFRS ADESCNQLTQ FMFSFCQKSR RQRIIQRNRT ERLSDLLDWR 600
    YLGRFYMHAR HLALSRSFPE KFRPEHLNLT STQGFRYPRP SSVPPSPSAS 650
    IHSTPHHSDE EDDDTYDEEE EAERDRLNIK APFSVGADTD GKRTQPVENG 700
    N 701
    Length:701
    Mass (Da):80,581
    Last modified:December 21, 2004 - v1
    Checksum:i66B767488D5FC820
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX649476 Genomic DNA. No translation available.
    BC095660 mRNA. Translation: AAH95660.1.
    RefSeqiNP_001018199.1. NM_001018679.1.
    UniGeneiDr.33913.

    Genome annotation databases

    EnsembliENSDART00000014007; ENSDARP00000002983; ENSDARG00000004904.
    GeneIDi373082.
    KEGGidre:373082.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX649476 Genomic DNA. No translation available.
    BC095660 mRNA. Translation: AAH95660.1 .
    RefSeqi NP_001018199.1. NM_001018679.1.
    UniGenei Dr.33913.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7955.ENSDARP00000002983.

    Protein family/group databases

    CAZyi GT3. Glycosyltransferase Family 3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSDART00000014007 ; ENSDARP00000002983 ; ENSDARG00000004904 .
    GeneIDi 373082.
    KEGGi dre:373082.

    Organism-specific databases

    CTDi 2998.
    ZFINi ZDB-GENE-030826-31. gys2.

    Phylogenomic databases

    eggNOGi COG0438.
    GeneTreei ENSGT00390000018612.
    HOGENOMi HOG000160890.
    HOVERGENi HBG001960.
    InParanoidi Q5RGX8.
    KOi K00693.
    OMAi EVSWEVT.
    OrthoDBi EOG741Z1N.
    TreeFami TF300306.

    Enzyme and pathway databases

    Reactomei REACT_180909. Glycogen synthesis.
    REACT_203198. Myoclonic epilepsy of Lafora.

    Miscellaneous databases

    NextBioi 20813355.
    PROi Q5RGX8.

    Family and domain databases

    InterProi IPR008631. Glycogen_synth.
    [Graphical view ]
    PANTHERi PTHR10176. PTHR10176. 1 hit.
    Pfami PF05693. Glycogen_syn. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LiverImported.
    2. "The zebrafish reference genome sequence and its relationship to the human genome."
      Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
      , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
      Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TuebingenImported.
    3. Ensembl
      Submitted (AUG-2013) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: TuebingenImported.

    Entry informationi

    Entry nameiQ5RGX8_DANRE
    AccessioniPrimary (citable) accession number: Q5RGX8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 21, 2004
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3