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Protein
Submitted name:

Pleckstrin homology domain-containing family A member 1

Gene

PLEKHA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Pleckstrin homology domain-containing family A member 1Imported
Gene namesi
Name:PLEKHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000107679.14.
HGNCiHGNC:14335. PLEKHA1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000107679.

PTM / Processingi

Proteomic databases

MaxQBiQ5RGS4.
PaxDbiQ5RGS4.
PeptideAtlasiQ5RGS4.
PRIDEiQ5RGS4.

Expressioni

Gene expression databases

BgeeiENSG00000107679.
ExpressionAtlasiQ5RGS4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5RGS4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 112PHInterPro annotationAdd BLAST106
Domaini191 – 289PHInterPro annotationAdd BLAST99

Phylogenomic databases

eggNOGiENOG410IF2M. Eukaryota.
ENOG410ZQEQ. LUCA.
GeneTreeiENSGT00440000037398.
HOGENOMiHOG000116175.
HOVERGENiHBG053612.

Family and domain databases

Gene3Di2.30.29.30. 2 hits.
InterProiView protein in InterPro
IPR011993. PH_dom-like.
IPR001849. PH_domain.
PfamiView protein in Pfam
PF00169. PH. 2 hits.
SMARTiView protein in SMART
SM00233. PH. 2 hits.
SUPFAMiSSF50729. SSF50729. 2 hits.
PROSITEiView protein in PROSITE
PS50003. PH_DOMAIN. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5RGS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPYVDRQNRI CGFLDIEENE NSGKFLRRYF ILDTREDSFV WYMDNPQNLP
60 70 80 90 100
SGSSRVGAIK LTYISKVSDA TKLRPKAEFC FVMNAGMRKY FLQANDQQDL
110 120 130 140 150
VEWVNVLNKA IKITVPKQSD SQPNSDNLSR HGECGKKQVS YRTDIVGGVP
160 170 180 190 200
IITPTQKEEV NECGESIDRN NLKRSQSHLP YFTPKPPQDS AVIKAGYCVK
210 220 230 240 250
QGAVMKNWKR RYFQLDENTI GYFKSELEKE PLRVIPLKEV HKVQECKQSD
260 270 280 290 300
IMMRDNLFEI VTTSRTFYVQ ADSPEEMHSW IKAVSGAIVA QRGPGRSASS
310 320 330 340 350
MRQARRLSNP CIQRSIPPVL QNPNTLSVLP TQPPPPHIPQ PLAATLWSQP
360 370 380
LPWRSEDFTS LLPRSSQGTS RSRLSLQENQ LPK
Length:383
Mass (Da):43,672
Last modified:December 21, 2004 - v1
Checksum:i38D43519C5DD7FE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX664700 Genomic DNA. No translation available.
BX842242 Genomic DNA. No translation available.
RefSeqiNP_001317107.1. NM_001330178.1.
XP_016871975.1. XM_017016486.1.
XP_016871976.1. XM_017016487.1.
XP_016871977.1. XM_017016488.1.
UniGeneiHs.643512.
Hs.738826.

Genome annotation databases

EnsembliENST00000368989; ENSP00000357985; ENSG00000107679.
GeneIDi59338.
UCSCiuc057wni.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5RGS4_HUMAN
AccessioniPrimary (citable) accession number: Q5RGS4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 27, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported