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Q5RGS2 (S31A2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Spermatogenesis-associated protein 31A2
Alternative name(s):
Protein FAM75A2
Gene names
Name:SPATA31A2
Synonyms:FAM75A2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length1347 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

May play a role in spermatogenesis By similarity.

Subcellular location

Membrane; Single-pass membrane protein Potential.

Sequence similarities

Belongs to the SPATA31 family.

Ontologies

Keywords
   Biological processDifferentiation
Spermatogenesis
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcell differentiation

Inferred from electronic annotation. Source: UniProtKB-KW

spermatogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 13471347Spermatogenesis-associated protein 31A2
PRO_0000297667

Regions

Transmembrane23 – 4321Helical; Potential
Compositional bias68 – 758Poly-Arg
Compositional bias120 – 228109Pro-rich
Compositional bias1333 – 13364Poly-His

Sequences

Sequence LengthMass (Da)Tools
Q5RGS2 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: AFFECC8723AFEAEA

FASTA1,347148,657
        10         20         30         40         50         60 
MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR CDDPPSPSPG 

        70         80         90        100        110        120 
KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LQETSDLLSQ LQSLLGPHLD KGDFGQLSGP 

       130        140        150        160        170        180 
DPPGEVGERA PDGASQSSHE PMEDAAPILS PLASPDPQAK HPQDLASTPS PGPMTTSVSS 

       190        200        210        220        230        240 
LSASQPPEPS LPLEHPSPEP PALFPHPPHT PDPLACSPPP PKGFTAPPLR DSTLITPSHC 

       250        260        270        280        290        300 
DSVALPLGTV PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 

       310        320        330        340        350        360 
HLSRHPPETY QMEAGSLFLL SSDGQNAVGI QVTETAKVNI WEEKENVGSF TDRMTPEKHL 

       370        380        390        400        410        420 
NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKFSD PRLWQESFWK NYSQLFWGLP 

       430        440        450        460        470        480 
SLHSESLVAN AWVTDRSYTL QSPPFLFNEM SNVCPIQRET TMSPLLFQAQ PPSHLGPECQ 

       490        500        510        520        530        540 
PFISSTPQFR PTPMAQAEAQ AHLQSSFPVL SPAFPSLIKN TGVACPASQN KVQALSLPET 

       550        560        570        580        590        600 
QHPEWPLLRR QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 

       610        620        630        640        650        660 
QHIKKWIIQH WGNLGRIQES LDLMQLRDES PGTSQAKGKP SPWQSSMSTG ESSKEAQKVK 

       670        680        690        700        710        720 
FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE SERNLRKPLR SDSGSDLLRC 

       730        740        750        760        770        780 
TERTHIENIL KAHMGRNLGQ TNEGLIPVRV RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK 

       790        800        810        820        830        840 
ACVNTAQVLS FLEPCTQQGL GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA 

       850        860        870        880        890        900 
GPSSATCESG AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 

       910        920        930        940        950        960 
GIPSWNDHGP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE TREAVPQCRV 

       970        980        990       1000       1010       1020 
PLETCMLANL QATSEDMHGF EAPGTSKSSL HPRVSVSQDP RKLCLMEEVV NEFEPGMATK 

      1030       1040       1050       1060       1070       1080 
SETQPQVCAA VVLLPDGQAS VVPHASENLV SQVPQGHLQS MPTGNMRASQ ELHDLMAARR 

      1090       1100       1110       1120       1130       1140 
SKLVHEEPRN PNCQGSCKSQ RPMFPPIHKS EKSRKPNLEK HEERLEGLRT PQLTPVRKTE 

      1150       1160       1170       1180       1190       1200 
DTHQDEGVQL LPSKKQPPSV SHFGGNIKQF FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY 

      1210       1220       1230       1240       1250       1260 
SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH RHLFYSEHGR 

      1270       1280       1290       1300       1310       1320 
ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ WGLRHPQILH PKKAVSPVSP 

      1330       1340 
LQHWPKTSGA SSHHHHCPRH CLLWEGI 

« Hide

References

[1]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX664726 Genomic DNA. Translation: CAI17100.1.
UniGeneHs.575677.

3D structure databases

ProteinModelPortalQ5RGS2.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ5RGS2.

Polymorphism databases

DMDM74743369.

Proteomic databases

PaxDbQ5RGS2.
PRIDEQ5RGS2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000456183; ENSP00000406957; ENSG00000204848.
KEGGhsa:642265.
UCSCuc004abm.3. human.

Organism-specific databases

GeneCardsGC09P039884.
HGNCHGNC:32002. SPATA31A2.
neXtProtNX_Q5RGS2.
PharmGKBPA162387854.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG45889.
HOGENOMHOG000015250.
HOVERGENHBG107892.
InParanoidQ5RGS2.
OMAKPQNPRN.
OrthoDBEOG7SFHVW.
PhylomeDBQ5RGS2.
TreeFamTF338531.

Gene expression databases

BgeeQ5RGS2.
GenevestigatorQ5RGS2.

Family and domain databases

InterProIPR027970. DUF4599.
[Graphical view]
PfamPF15371. DUF4599. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi642265.
NextBio113592.
PROQ5RGS2.

Entry information

Entry nameS31A2_HUMAN
AccessionPrimary (citable) accession number: Q5RGS2
Entry history
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM