SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5RGS2

- S31A2_HUMAN

UniProt

Q5RGS2 - S31A2_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Spermatogenesis-associated protein 31A2
Gene
SPATA31A2, FAM75A2
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

May play a role in spermatogenesis By similarity.

GO - Biological processi

  1. cell differentiation Source: UniProtKB-KW
  2. spermatogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Differentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 31A2
Alternative name(s):
Protein FAM75A2
Gene namesi
Synonyms:FAM75A2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:32002. SPATA31A2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei23 – 4321Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162387854.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13471347Spermatogenesis-associated protein 31A2
PRO_0000297667Add
BLAST

Proteomic databases

PaxDbiQ5RGS2.
PRIDEiQ5RGS2.

PTM databases

PhosphoSiteiQ5RGS2.

Expressioni

Gene expression databases

BgeeiQ5RGS2.
GenevestigatoriQ5RGS2.

Structurei

3D structure databases

ProteinModelPortaliQ5RGS2.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi68 – 758Poly-Arg
Compositional biasi120 – 228109Pro-rich
Add
BLAST
Compositional biasi1333 – 13364Poly-His

Sequence similaritiesi

Belongs to the SPATA31 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG45889.
HOGENOMiHOG000015250.
HOVERGENiHBG107892.
InParanoidiQ5RGS2.
OMAiKPQNPRN.
OrthoDBiEOG7SFHVW.
PhylomeDBiQ5RGS2.
TreeFamiTF338531.

Family and domain databases

InterProiIPR027970. DUF4599.
[Graphical view]
PfamiPF15371. DUF4599. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5RGS2-1 [UniParc]FASTAAdd to Basket

« Hide

MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR     50
CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LQETSDLLSQ 100
LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS 150
PLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP 200
PALFPHPPHT PDPLACSPPP PKGFTAPPLR DSTLITPSHC DSVALPLGTV 250
PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 300
HLSRHPPETY QMEAGSLFLL SSDGQNAVGI QVTETAKVNI WEEKENVGSF 350
TDRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKFSD 400
PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM 450
SNVCPIQRET TMSPLLFQAQ PPSHLGPECQ PFISSTPQFR PTPMAQAEAQ 500
AHLQSSFPVL SPAFPSLIKN TGVACPASQN KVQALSLPET QHPEWPLLRR 550
QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 600
QHIKKWIIQH WGNLGRIQES LDLMQLRDES PGTSQAKGKP SPWQSSMSTG 650
ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE 700
SERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV 750
RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL 800
GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG 850
AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 900
GIPSWNDHGP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE 950
TREAVPQCRV PLETCMLANL QATSEDMHGF EAPGTSKSSL HPRVSVSQDP 1000
RKLCLMEEVV NEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV 1050
SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRN PNCQGSCKSQ 1100
RPMFPPIHKS EKSRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL 1150
LPSKKQPPSV SHFGGNIKQF FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY 1200
SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH 1250
RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ 1300
WGLRHPQILH PKKAVSPVSP LQHWPKTSGA SSHHHHCPRH CLLWEGI 1347
Length:1,347
Mass (Da):148,657
Last modified:December 21, 2004 - v1
Checksum:iAFFECC8723AFEAEA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX664726 Genomic DNA. Translation: CAI17100.1.
UniGeneiHs.575677.

Genome annotation databases

EnsembliENST00000456183; ENSP00000406957; ENSG00000204848.
KEGGihsa:642265.
UCSCiuc004abm.3. human.

Polymorphism databases

DMDMi74743369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX664726 Genomic DNA. Translation: CAI17100.1 .
UniGenei Hs.575677.

3D structure databases

ProteinModelPortali Q5RGS2.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q5RGS2.

Polymorphism databases

DMDMi 74743369.

Proteomic databases

PaxDbi Q5RGS2.
PRIDEi Q5RGS2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000456183 ; ENSP00000406957 ; ENSG00000204848 .
KEGGi hsa:642265.
UCSCi uc004abm.3. human.

Organism-specific databases

GeneCardsi GC09P039884.
HGNCi HGNC:32002. SPATA31A2.
neXtProti NX_Q5RGS2.
PharmGKBi PA162387854.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG45889.
HOGENOMi HOG000015250.
HOVERGENi HBG107892.
InParanoidi Q5RGS2.
OMAi KPQNPRN.
OrthoDBi EOG7SFHVW.
PhylomeDBi Q5RGS2.
TreeFami TF338531.

Miscellaneous databases

GenomeRNAii 642265.
NextBioi 113592.
PROi Q5RGS2.

Gene expression databases

Bgeei Q5RGS2.
Genevestigatori Q5RGS2.

Family and domain databases

InterProi IPR027970. DUF4599.
[Graphical view ]
Pfami PF15371. DUF4599. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiS31A2_HUMAN
AccessioniPrimary (citable) accession number: Q5RGS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi