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Q5RGS2

- S31A2_HUMAN

UniProt

Q5RGS2 - S31A2_HUMAN

Protein

Spermatogenesis-associated protein 31A2

Gene

SPATA31A2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Functioni

    May play a role in spermatogenesis.By similarity

    GO - Biological processi

    1. cell differentiation Source: UniProtKB-KW
    2. spermatogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Differentiation, Spermatogenesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Spermatogenesis-associated protein 31A2
    Alternative name(s):
    Protein FAM75A2
    Gene namesi
    Name:SPATA31A2
    Synonyms:FAM75A2
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:32002. SPATA31A2.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162387854.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13471347Spermatogenesis-associated protein 31A2PRO_0000297667Add
    BLAST

    Proteomic databases

    PaxDbiQ5RGS2.
    PRIDEiQ5RGS2.

    PTM databases

    PhosphoSiteiQ5RGS2.

    Expressioni

    Gene expression databases

    BgeeiQ5RGS2.
    GenevestigatoriQ5RGS2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5RGS2.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei23 – 4321HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi68 – 758Poly-Arg
    Compositional biasi120 – 228109Pro-richAdd
    BLAST
    Compositional biasi1333 – 13364Poly-His

    Sequence similaritiesi

    Belongs to the SPATA31 family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG45889.
    HOGENOMiHOG000015250.
    HOVERGENiHBG107892.
    InParanoidiQ5RGS2.
    OMAiKPQNPRN.
    OrthoDBiEOG7SFHVW.
    PhylomeDBiQ5RGS2.
    TreeFamiTF338531.

    Family and domain databases

    InterProiIPR027970. DUF4599.
    [Graphical view]
    PfamiPF15371. DUF4599. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5RGS2-1 [UniParc]FASTAAdd to Basket

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    MENLPFPLKL LSASSLNAPS STPWVLDIFL TLVFALGFFF LLLPYLSYFR     50
    CDDPPSPSPG KRKCPVGRRR RPRGRMKNHS LRAGRECRRG LQETSDLLSQ 100
    LQSLLGPHLD KGDFGQLSGP DPPGEVGERA PDGASQSSHE PMEDAAPILS 150
    PLASPDPQAK HPQDLASTPS PGPMTTSVSS LSASQPPEPS LPLEHPSPEP 200
    PALFPHPPHT PDPLACSPPP PKGFTAPPLR DSTLITPSHC DSVALPLGTV 250
    PQSLSPHEDL VASVPAISGL GGSNSHVSAS SRWQETARTS CAFNSSVQQD 300
    HLSRHPPETY QMEAGSLFLL SSDGQNAVGI QVTETAKVNI WEEKENVGSF 350
    TDRMTPEKHL NSLRNLAKSL DAEQDTTNPK PFWNMGENSK QLPGPQKFSD 400
    PRLWQESFWK NYSQLFWGLP SLHSESLVAN AWVTDRSYTL QSPPFLFNEM 450
    SNVCPIQRET TMSPLLFQAQ PPSHLGPECQ PFISSTPQFR PTPMAQAEAQ 500
    AHLQSSFPVL SPAFPSLIKN TGVACPASQN KVQALSLPET QHPEWPLLRR 550
    QLEGRLALPS RVQKSQDVFS VSTPNLPQES LTSILPENFP VSPELRRQLE 600
    QHIKKWIIQH WGNLGRIQES LDLMQLRDES PGTSQAKGKP SPWQSSMSTG 650
    ESSKEAQKVK FQLERDPCPH LGQILGETPQ NLSRDMKSFP RKVLGVTSEE 700
    SERNLRKPLR SDSGSDLLRC TERTHIENIL KAHMGRNLGQ TNEGLIPVRV 750
    RRSWLAVNQA LPVSNTHVKT SNLAAPKSGK ACVNTAQVLS FLEPCTQQGL 800
    GAHIVRFWAK HRWGLPLRVL KPIQCFKLEK VSSLSLTQLA GPSSATCESG 850
    AGSEVEVDMF LRKPPMASLR KQVLTKASDH MPESLLASSP AWKQFQRAPR 900
    GIPSWNDHGP LKPPPAGQEG RWPSKPLTYS LTGSTQQSRS LGAQSSKAGE 950
    TREAVPQCRV PLETCMLANL QATSEDMHGF EAPGTSKSSL HPRVSVSQDP 1000
    RKLCLMEEVV NEFEPGMATK SETQPQVCAA VVLLPDGQAS VVPHASENLV 1050
    SQVPQGHLQS MPTGNMRASQ ELHDLMAARR SKLVHEEPRN PNCQGSCKSQ 1100
    RPMFPPIHKS EKSRKPNLEK HEERLEGLRT PQLTPVRKTE DTHQDEGVQL 1150
    LPSKKQPPSV SHFGGNIKQF FQWIFSKKKS KPAPVTAESQ KTVKNRSCVY 1200
    SSSAEAQGLM TAVGQMLDEK MSLCHARHAS KVNQHKQKFQ APVCGFPCNH 1250
    RHLFYSEHGR ILSYAASSQQ ATLKSQGCPN RDRQIRNQQP LKSVRCNNEQ 1300
    WGLRHPQILH PKKAVSPVSP LQHWPKTSGA SSHHHHCPRH CLLWEGI 1347
    Length:1,347
    Mass (Da):148,657
    Last modified:December 21, 2004 - v1
    Checksum:iAFFECC8723AFEAEA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX664726 Genomic DNA. Translation: CAI17100.1.
    UniGeneiHs.575677.

    Genome annotation databases

    KEGGihsa:642265.
    UCSCiuc004abm.3. human.

    Polymorphism databases

    DMDMi74743369.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX664726 Genomic DNA. Translation: CAI17100.1 .
    UniGenei Hs.575677.

    3D structure databases

    ProteinModelPortali Q5RGS2.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q5RGS2.

    Polymorphism databases

    DMDMi 74743369.

    Proteomic databases

    PaxDbi Q5RGS2.
    PRIDEi Q5RGS2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    KEGGi hsa:642265.
    UCSCi uc004abm.3. human.

    Organism-specific databases

    GeneCardsi GC09P039884.
    HGNCi HGNC:32002. SPATA31A2.
    neXtProti NX_Q5RGS2.
    PharmGKBi PA162387854.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG45889.
    HOGENOMi HOG000015250.
    HOVERGENi HBG107892.
    InParanoidi Q5RGS2.
    OMAi KPQNPRN.
    OrthoDBi EOG7SFHVW.
    PhylomeDBi Q5RGS2.
    TreeFami TF338531.

    Miscellaneous databases

    GenomeRNAii 642265.
    NextBioi 113592.
    PROi Q5RGS2.

    Gene expression databases

    Bgeei Q5RGS2.
    Genevestigatori Q5RGS2.

    Family and domain databases

    InterProi IPR027970. DUF4599.
    [Graphical view ]
    Pfami PF15371. DUF4599. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiS31A2_HUMAN
    AccessioniPrimary (citable) accession number: Q5RGS2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 21, 2007
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3