Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5RGN0 (NBPFN_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative neuroblastoma breakpoint family member 24
Gene names
Name:NBPF24
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length790 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Miscellaneous

Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

Sequence similarities

Belongs to the NBPF family.

Contains 6 NBPF domains.

Caution

Could be the product of a pseudogene.

Ontologies

Keywords
   DomainCoiled coil
Repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 790790Putative neuroblastoma breakpoint family member 24
PRO_0000405313

Regions

Domain90 – 18495NBPF 1
Domain361 – 45393NBPF 2
Domain454 – 54289NBPF 3
Domain545 – 60056NBPF 4
Domain601 – 69292NBPF 5
Domain695 – 79096NBPF 6
Coiled coil14 – 5542 Potential
Coiled coil264 – 32663 Potential

Sequences

Sequence LengthMass (Da)Tools
Q5RGN0 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: DCC4C07DA3050DA1

FASTA79090,230
        10         20         30         40         50         60 
MFSNSTGRLP GQPTQEIQQY KVLVHSQERE LTQLREKLRE GRDASRSLNE HLQALLTPDE 

        70         80         90        100        110        120 
PDKSQGQDLQ EQLAEGCRLA QHLVQKLSPE NDEDEDEDVQ VEEDEKVLES SAPREVQKAE 

       130        140        150        160        170        180 
ESKVPEDSLE ECAITCSNSH GPCDSIQPHK NIKITFEEDK VNSSLVVDRE SSHDGCQDAL 

       190        200        210        220        230        240 
NILPVPGPTS SATNVSMVVS AGPLSSEKAE MNILEINEKL CPQLAEKKQQ FRSLKEKCFV 

       250        260        270        280        290        300 
TQVACFLAKQ QNKYKYEECK DLIKSMLRNE RQFKEEKLAE QLKQAEELRQ YKVLVHSQER 

       310        320        330        340        350        360 
ELTQLREKLR EGRDASRSLN EHLQALLTPD EPDKSQGQDL QEQLAEGCRL AQHLVQKLSP 

       370        380        390        400        410        420 
ENDNDDDEDV QVEVAEKVQK SSSPREMQKA EEKEVPEDSL EECAITCSNS HGPYDSNQPH 

       430        440        450        460        470        480 
RKTKITFEED KVDSTLIGSS SHVEWEDAVH IIPENESDDE EEEEKGPVSP RNLQESEEEE 

       490        500        510        520        530        540 
VPQESWDEGY STLSIPPERL ASYQSYSSTF HSLEEQQVCM AVDIGRHRWD QVKKEDQEAT 

       550        560        570        580        590        600 
GPRLSRELLD EKEPEVLQDS LDRCYSTPSV YLGLTDSCQP YRSAFYVLEQ QRIGLAVDMD 

       610        620        630        640        650        660 
EIEKYQEVEE DQDPSCPRLS RELLAEKEPE VLQDSLDRCY STPSGYLELP DLGQPYRSAV 

       670        680        690        700        710        720 
YSLEEQYLGL ALDVDRIKKD QEEEEDQGPP CPRLSRELLE VVEPEVLQDS LDVIQLLPVV 

       730        740        750        760        770        780 
LNSLTPASPT EVPFMHWRKN MLAFLLTWEK LKRRGRGRKE GEEDQRRKEE GEEKKGKKIK 

       790 
THHAPGSAAC 

« Hide

References

[1]"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. expand/collapse author list , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX842679 Genomic DNA. Translation: CAI23637.1.
UniGeneHs.721588.
Hs.730358.
Hs.740943.
Hs.744018.

3D structure databases

ProteinModelPortalQ5RGN0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid609324. 1 interaction.

Proteomic databases

PaxDbQ5RGN0.
PRIDEQ5RGN0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc001eox.3. human.

Organism-specific databases

GeneCardsGC01M147575.
HGNCHGNC:27299. NBPF24.
neXtProtNX_Q5RGN0.
PharmGKBPA165752039.
GenAtlasSearch...

Phylogenomic databases

eggNOGbiNOG22098.
HOGENOMHOG000049041.
HOVERGENHBG058300.
TreeFamTF341151.

Gene expression databases

ArrayExpressQ5RGN0.
BgeeQ5RGN0.

Family and domain databases

InterProIPR010630. NBPF_dom.
[Graphical view]
PfamPF06758. DUF1220. 6 hits.
[Graphical view]
PROSITEPS51316. NBPF. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio13622359.

Entry information

Entry nameNBPFN_HUMAN
AccessionPrimary (citable) accession number: Q5RGN0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: December 21, 2004
Last modified: March 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 1

Human chromosome 1: entries, gene names and cross-references to MIM