Q5RGN0 (NBPFN_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative neuroblastoma breakpoint family member 24

Gene names

Name:

NBPF24

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	790 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Miscellaneous	Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.
Sequence similarities	Belongs to the NBPF family. Contains 6 NBPF domains.
Caution	Could be the product of a pseudogene.

Ontologies

Keywords
Domain	Coiled coil Repeat
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 790	790	Putative neuroblastoma breakpoint family member 24		PRO_0000405313
Regions
	Domain	90 – 184	95	NBPF 1
	Domain	361 – 453	93	NBPF 2
	Domain	454 – 542	89	NBPF 3
	Domain	545 – 600	56	NBPF 4
	Domain	601 – 692	92	NBPF 5
	Domain	695 – 790	96	NBPF 6
	Coiled coil	14 – 55	42	Potential
	Coiled coil	264 – 326	63	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5RGN0 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: DCC4C07DA3050DA1	FASTA	790	90,230
	10 20 30 40 50 60 MFSNSTGRLP GQPTQEIQQY KVLVHSQERE LTQLREKLRE GRDASRSLNE HLQALLTPDE 70 80 90 100 110 120 PDKSQGQDLQ EQLAEGCRLA QHLVQKLSPE NDEDEDEDVQ VEEDEKVLES SAPREVQKAE 130 140 150 160 170 180 ESKVPEDSLE ECAITCSNSH GPCDSIQPHK NIKITFEEDK VNSSLVVDRE SSHDGCQDAL 190 200 210 220 230 240 NILPVPGPTS SATNVSMVVS AGPLSSEKAE MNILEINEKL CPQLAEKKQQ FRSLKEKCFV 250 260 270 280 290 300 TQVACFLAKQ QNKYKYEECK DLIKSMLRNE RQFKEEKLAE QLKQAEELRQ YKVLVHSQER 310 320 330 340 350 360 ELTQLREKLR EGRDASRSLN EHLQALLTPD EPDKSQGQDL QEQLAEGCRL AQHLVQKLSP 370 380 390 400 410 420 ENDNDDDEDV QVEVAEKVQK SSSPREMQKA EEKEVPEDSL EECAITCSNS HGPYDSNQPH 430 440 450 460 470 480 RKTKITFEED KVDSTLIGSS SHVEWEDAVH IIPENESDDE EEEEKGPVSP RNLQESEEEE 490 500 510 520 530 540 VPQESWDEGY STLSIPPERL ASYQSYSSTF HSLEEQQVCM AVDIGRHRWD QVKKEDQEAT 550 560 570 580 590 600 GPRLSRELLD EKEPEVLQDS LDRCYSTPSV YLGLTDSCQP YRSAFYVLEQ QRIGLAVDMD 610 620 630 640 650 660 EIEKYQEVEE DQDPSCPRLS RELLAEKEPE VLQDSLDRCY STPSGYLELP DLGQPYRSAV 670 680 690 700 710 720 YSLEEQYLGL ALDVDRIKKD QEEEEDQGPP CPRLSRELLE VVEPEVLQDS LDVIQLLPVV 730 740 750 760 770 780 LNSLTPASPT EVPFMHWRKN MLAFLLTWEK LKRRGRGRKE GEEDQRRKEE GEEKKGKKIK 790 THHAPGSAAC

References

[1]

"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842679 Genomic DNA. Translation: CAI23637.1.
IPI	IPI00943573.
UniGene	Hs.721588. Hs.730358. Hs.740943. Hs.744018.
3D structure databases
ProteinModelPortal	Q5RGN0.
ModBase	Search...
Proteomic databases
PaxDb	Q5RGN0.
PRIDE	Q5RGN0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000369226; ENSP00000358228; ENSG00000203836.
UCSC	uc001eox.3. human.
Organism-specific databases
GeneCards	GC01M147575.
HGNC	HGNC:27299. NBPF24.
neXtProt	NX_Q5RGN0.
PharmGKB	PA165752039.
GenAtlas	Search...
Phylogenomic databases
eggNOG	biNOG22098.
HOGENOM	HOG000049041.
HOVERGEN	HBG058300.
Gene expression databases
ArrayExpress	Q5RGN0.
Bgee	Q5RGN0.
Family and domain databases
InterPro	IPR010630. NBPF_dom. [Graphical view]
Pfam	PF06758. DUF1220. 6 hits. [Graphical view]
PROSITE	PS51316. NBPF. 6 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	13622359.

Entry information

Entry name

NBPFN_HUMAN

Accession

Primary (citable) accession number: Q5RGN0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 8, 2011
Last sequence update:	December 21, 2004
Last modified:	May 29, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.