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Protein
Submitted name:

Uncharacterized protein

Gene

kcnk5b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • fin development Source: ZFIN
  • fin morphogenesis Source: ZFIN
  • regulation of membrane potential Source: ZFIN
  • stabilization of membrane potential Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:kcnk5bImported
Synonyms:kcnk5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 20

Organism-specific databases

ZFINiZDB-GENE-040426-1297. kcnk5b.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 26HelicalSequence analysisAdd BLAST20
Transmembranei116 – 137HelicalSequence analysisAdd BLAST22
Transmembranei158 – 185HelicalSequence analysisAdd BLAST28
Transmembranei229 – 250HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ5RGB0.

Expressioni

Gene expression databases

BgeeiENSDARG00000012390.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015031.

Structurei

3D structure databases

ProteinModelPortaliQ5RGB0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 137Ion_trans_2InterPro annotationAdd BLAST62
Domaini171 – 249Ion_trans_2InterPro annotationAdd BLAST79

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00760000118858.
HOGENOMiHOG000113211.
HOVERGENiHBG052236.
InParanoidiQ5RGB0.
OMAiCILYGLC.
OrthoDBiEOG091G058Z.
TreeFamiTF313947.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR003092. 2pore_dom_K_chnl_TASK.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
PR01095. TASKCHANNEL.

Sequencei

Sequence statusi: Complete.

Q5RGB0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADKGPILTS VIIFYLSIGA AIFQILEEPN LNSAVDDYKN KTNNLLKKYP
60 70 80 90 100
CLSKEVLGEI IEVVAEATGQ GVTVTKEAQF NNWNWENAVI FAATVITTIG
110 120 130 140 150
YGNVAPKTTG GRLFCILYGL CGIPLCLTWI SELGTFFGSR TKRLSQLLLH
160 170 180 190 200
SGLNVRKVQF ICTIVFLLWG FLVHLIIPAF VFMFFENWTY LEGLYFSFTT
210 220 230 240 250
LTTVGFGDYV AGVDPSVNYP TLYRFFVQLW IYLGLAWLSL FFSWNVHMVV
260 270 280 290 300
EAHKVLKKRR MRRHRLPTDD VPEKKEVKKT PKPPPRSGVI DIFEFMSEKV
310 320 330 340 350
EDYSDVIRAI GADEKRRKKK QEEELARSKS CSDLLQGLVI PLDHSPRLQR
360 370 380 390 400
RFSVSANMCM AISDESVDGL NNNNCKQEDD TLTKVRHKDQ KVNRERAENP
410 420 430 440
ARCAWDSRSS DPSIFQSSTV TNSTNRGSRF SVSKVSEDRL LGKRKSFG
Length:448
Mass (Da):50,849
Last modified:December 21, 2004 - v1
Checksum:iBDE07FAB7930A1B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX942841 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000023293; ENSDARP00000015031; ENSDARG00000012390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX942841 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5RGB0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000015031.

Proteomic databases

PaxDbiQ5RGB0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000023293; ENSDARP00000015031; ENSDARG00000012390.

Organism-specific databases

ZFINiZDB-GENE-040426-1297. kcnk5b.

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
GeneTreeiENSGT00760000118858.
HOGENOMiHOG000113211.
HOVERGENiHBG052236.
InParanoidiQ5RGB0.
OMAiCILYGLC.
OrthoDBiEOG091G058Z.
TreeFamiTF313947.

Gene expression databases

BgeeiENSDARG00000012390.

Family and domain databases

InterProiIPR003280. 2pore_dom_K_chnl.
IPR003092. 2pore_dom_K_chnl_TASK.
IPR013099. K_chnl_dom.
[Graphical view]
PfamiPF07885. Ion_trans_2. 2 hits.
[Graphical view]
PRINTSiPR01333. 2POREKCHANEL.
PR01095. TASKCHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5RGB0_DANRE
AccessioniPrimary (citable) accession number: Q5RGB0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: October 5, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.