Q5RCM7 (DJC16_PONAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DnaJ homolog subfamily C member 16

Gene names

Name:

DNAJC16

Organism

Pongo abelii (Sumatran orangutan)

Taxonomic identifier

9601 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo

Protein attributes

Sequence length	782 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Single-pass type IV membrane protein Potential.
Sequence similarities	Contains 1 J domain. Contains 1 thioredoxin domain.

Ontologies

Keywords
Cellular component	Membrane
Domain	Signal Transmembrane Transmembrane helix
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro protein folding Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	heat shock protein binding Inferred from electronic annotation. Source: InterPro unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Potential
	Chain	26 – 782	757	DnaJ homolog subfamily C member 16		PRO_0000236685
Regions
	Topological domain	26 – 535	510	Cytoplasmic Potential
	Transmembrane	536 – 556	21	Helical; Anchor for type IV membrane protein; Potential
	Topological domain	557 – 782	226	Extracellular Potential
	Domain	29 – 93	65	J
	Domain	119 – 247	129	Thioredoxin
	Compositional bias	102 – 107	6	Poly-Gln
	Compositional bias	718 – 721	4	Poly-Glu
Amino acid modifications
	Glycosylation	631	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q5RCM7 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: EDC48FC96D9D96BE	FASTA	782	90,332
	10 20 30 40 50 60 MEVRKLSISW QFLIVLVLIL QILSALDFDP YKVLGVSRTA SQADIKKAYK KLAREWHPDK 70 80 90 100 110 120 NKDPGAEDKF IQISKAYEIL SNEEKRSNYD QYGDAGENQG YQKQQQQREY RFRHFHENFY 130 140 150 160 170 180 FDESFFHFPF NSERRDSIDE KYLLHFSHYV NEVVPDSFKK PYLIKITSDW CFSCIHIEPV 190 200 210 220 230 240 WKEVVQELEE LGVGIGVVHA GYERRLAHHL GAHSTPSILG IINGKISFFR NAVVRENLRQ 250 260 270 280 290 300 FVESLLPGNL VEKVTGKNYV RFLSGWQQEN KPHVLLFDQT PIVPLLYKLT AFAYKDYLSF 310 320 330 340 350 360 GYVYVGLRGT EEMTRRYNIN IYAPTLLVFK EHINKPADVI QARGMKKQII DDFITQNKHL 370 380 390 400 410 420 LAARLTSQKL FHELCPVRRS HRQRKYCVVL LTAETTKLSK PFEAFLSFAL ANTQDTVRFV 430 440 450 460 470 480 HVYSNRQQEF AGTLLPDGEA FQGKSAVSIL ERRNTAGRVV YKTLEDPWTG SESDKFILLG 490 500 510 520 530 540 YLDQLRKDPA LLSSEAVLPD LTDELAPVFL LRWFYSACDY ISDCWDSIFH NNWREMMPLL 550 560 570 580 590 600 SLIFSALFIL FGTVIVQAFS DSSDERESSP PDKEEAQEKT GKTEPSFTKE NSSKIPKKGF 610 620 630 640 650 660 VEVTELTDVT YTSNLVRLRP GHMNVVLILS NSTKTSLLQK FALEVYTFTG SSCLHFSFLS 670 680 690 700 710 720 LDKHREWLEY LLEFAQDAAP IPNQYDKHFM ERDYTGYVLA LNGHKKYFCL FKPQKTVEEE 730 740 750 760 770 780 EAIGSCSDVD SSLYLGESRG KPSCGLGSRP IKGKLSKLSL WMERLLEGSL QRFYIPSWPE LD

References

[1]	The German cDNA consortium Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Kidney.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR858243 mRNA. Translation: CAH90480.1.
RefSeq	NP_001125250.1. NM_001131778.1.
UniGene	Pab.11404.
3D structure databases
ProteinModelPortal	Q5RCM7.
SMR	Q5RCM7. Positions 19-100.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	100172145.
KEGG	pon:100172145.
Organism-specific databases
CTD	23341.
Phylogenomic databases
HOVERGEN	HBG055742.
InParanoid	Q5RCM7.
Family and domain databases
InterPro	IPR001623. DnaJ_N. IPR018253. Heat_shock_DnaJ_CS. IPR003095. Hsp_DnaJ. IPR012336. Thioredoxin-like_fold. IPR013766. Thioredoxin_domain. [Graphical view]
Gene3D	G3DSA:1.10.287.110. DnaJ_N. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KO	K09536.
Pfam	PF00226. DnaJ. 1 hit. PF00085. Thioredoxin. 1 hit. [Graphical view]
PRINTS	PR00625. JDOMAIN.
SMART	SM00271. DnaJ. 1 hit. [Graphical view]
SUPFAM	SSF46565. DnaJ_N. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS00636. DNAJ_1. 1 hit. PS50076. DNAJ_2. 1 hit. PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DJC16_PONAB

Accession

Primary (citable) accession number: Q5RCM7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	December 21, 2004
Last modified:	November 16, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program