SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5RBS3

- SERPH_PONAB

UniProt

Q5RBS3 - SERPH_PONAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Serpin H1

Gene
SERPINH1
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei376 – 3772Reactive bond homolog By similarity

Keywords - Molecular functioni

Chaperone

Protein family/group databases

MEROPSiI04.036.

Names & Taxonomyi

Protein namesi
Recommended name:
Serpin H1
Alternative name(s):
Collagen-binding protein
Short name:
Colligin
Gene namesi
Name:SERPINH1
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595: Unplaced

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum lumen Source: UniProtKB-SubCell
  2. extracellular space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 Reviewed predictionAdd
BLAST
Chaini19 – 417399Serpin H1PRO_0000253605Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei94 – 941N6-succinyllysine By similarity
Glycosylationi120 – 1201N-linked (GlcNAc...) Reviewed prediction
Glycosylationi125 – 1251N-linked (GlcNAc...) Reviewed prediction
Modified residuei206 – 2061N6-acetyllysine By similarity
Modified residuei295 – 2951N6-succinyllysine By similarity
Modified residuei318 – 3181N6-acetyllysine By similarity

Keywords - PTMi

Acetylation, Glycoprotein

Proteomic databases

PRIDEiQ5RBS3.

Structurei

3D structure databases

ProteinModelPortaliQ5RBS3.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi414 – 4174Prevents secretion from ER Reviewed prediction

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi25 – 295Poly-Ala

Sequence similaritiesi

Belongs to the serpin family.

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG104930.
KOiK09501.

Family and domain databases

InterProiIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiPF00079. Serpin. 1 hit.
[Graphical view]
SMARTiSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00284. SERPIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5RBS3-1 [UniParc]FASTAAdd to Basket

« Hide

MRSLLLLSAF CLLEAALAAE VKKPAAAAAP GTAEKLSPKA ATLAERSAGL    50
AFSLYQAMAK DQAVENILVS PVVVASSLGL VSLGGKATTA SQAKAVLSAE 100
QLRDEEVHAG LGELLRSLSN STARNVTWKL GSRLYGPSSV SFADDFVRTA 150
SSTTTASTPR STSATSAALQ SINEWAAQTT DGKLPEVTKD VERTDGALLV 200
NAMFFKPHWD EKFHHKMVDN RGFMVTRSYT VGVMMMHRTG LYNYYDDEKE 250
KLQIVEMPLA HKLSSLIILM PHHVEPLERL EKLLTKEQLK IWMGKMQKKA 300
VAISLPKGVV EVTHDLQKHL AGLGLTEAID KNKADLSRMS GKKDLYLASV 350
FHATAFELDT DGNPFDQDIY GREELRSPKL FYADHPFIFL VRDTQSGSLL 400
FIGRLVRPKG DKMRDEL 417
Length:417
Mass (Da):45,762
Last modified:December 21, 2004 - v1
Checksum:iBF7BA00DAC59FEC1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR858522 mRNA. Translation: CAH90749.1.
CR858561 mRNA. Translation: CAH90787.1.
RefSeqiNP_001125445.1. NM_001131973.1.
UniGeneiPab.17407.

Genome annotation databases

GeneIDi100172353.
KEGGipon:100172353.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR858522 mRNA. Translation: CAH90749.1 .
CR858561 mRNA. Translation: CAH90787.1 .
RefSeqi NP_001125445.1. NM_001131973.1.
UniGenei Pab.17407.

3D structure databases

ProteinModelPortali Q5RBS3.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I04.036.

Proteomic databases

PRIDEi Q5RBS3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100172353.
KEGGi pon:100172353.

Organism-specific databases

CTDi 871.

Phylogenomic databases

HOVERGENi HBG104930.
KOi K09501.

Family and domain databases

InterProi IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view ]
PANTHERi PTHR11461. PTHR11461. 1 hit.
Pfami PF00079. Serpin. 1 hit.
[Graphical view ]
SMARTi SM00093. SERPIN. 1 hit.
[Graphical view ]
SUPFAMi SSF56574. SSF56574. 1 hit.
PROSITEi PS00014. ER_TARGET. 1 hit.
PS00284. SERPIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. The German cDNA consortium
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Heart.

Entry informationi

Entry nameiSERPH_PONAB
AccessioniPrimary (citable) accession number: Q5RBS3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: December 21, 2004
Last modified: March 19, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi