Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5RBS3 (SERPH_PONAB) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serpin H1
Alternative name(s):
Collagen-binding protein
Short name=Colligin
Gene names
Name:SERPINH1
OrganismPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) [Reference proteome]
Taxonomic identifier9601 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen By similarity.

Subcellular location

Endoplasmic reticulum lumen By similarity.

Sequence similarities

Belongs to the serpin family.

Ontologies

Keywords
   Cellular componentEndoplasmic reticulum
   DomainSignal
   Molecular functionChaperone
   PTMAcetylation
Glycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

extracellular space

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 417399Serpin H1
PRO_0000253605

Regions

Motif414 – 4174Prevents secretion from ER Potential
Compositional bias25 – 295Poly-Ala

Sites

Site376 – 3772Reactive bond homolog By similarity

Amino acid modifications

Modified residue941N6-succinyllysine By similarity
Modified residue2061N6-acetyllysine By similarity
Modified residue2951N6-succinyllysine By similarity
Modified residue3181N6-acetyllysine By similarity
Glycosylation1201N-linked (GlcNAc...) Potential
Glycosylation1251N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q5RBS3 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: BF7BA00DAC59FEC1

FASTA41745,762
        10         20         30         40         50         60 
MRSLLLLSAF CLLEAALAAE VKKPAAAAAP GTAEKLSPKA ATLAERSAGL AFSLYQAMAK 

        70         80         90        100        110        120 
DQAVENILVS PVVVASSLGL VSLGGKATTA SQAKAVLSAE QLRDEEVHAG LGELLRSLSN 

       130        140        150        160        170        180 
STARNVTWKL GSRLYGPSSV SFADDFVRTA SSTTTASTPR STSATSAALQ SINEWAAQTT 

       190        200        210        220        230        240 
DGKLPEVTKD VERTDGALLV NAMFFKPHWD EKFHHKMVDN RGFMVTRSYT VGVMMMHRTG 

       250        260        270        280        290        300 
LYNYYDDEKE KLQIVEMPLA HKLSSLIILM PHHVEPLERL EKLLTKEQLK IWMGKMQKKA 

       310        320        330        340        350        360 
VAISLPKGVV EVTHDLQKHL AGLGLTEAID KNKADLSRMS GKKDLYLASV FHATAFELDT 

       370        380        390        400        410 
DGNPFDQDIY GREELRSPKL FYADHPFIFL VRDTQSGSLL FIGRLVRPKG DKMRDEL 

« Hide

References

[1]The German cDNA consortium
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Heart.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR858522 mRNA. Translation: CAH90749.1.
CR858561 mRNA. Translation: CAH90787.1.
RefSeqNP_001125445.1. NM_001131973.1.
UniGenePab.17407.

3D structure databases

ProteinModelPortalQ5RBS3.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSI04.036.

Proteomic databases

PRIDEQ5RBS3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100172353.
KEGGpon:100172353.

Organism-specific databases

CTD871.

Phylogenomic databases

HOVERGENHBG104930.
KOK09501.

Family and domain databases

InterProIPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. SSF56574. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSERPH_PONAB
AccessionPrimary (citable) accession number: Q5RBS3
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: December 21, 2004
Last modified: March 19, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families