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Protein

Protein MTO1 homolog, mitochondrial

Gene

MTO1

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the 5-carboxymethylaminomethyl modification (mnm5s2U34) of the wobble uridine base in mitochondrial tRNAs.By similarity

Cofactori

FADBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi43 – 486FADBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MTO1 homolog, mitochondrial
Gene namesi
Name:MTO1
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2525MitochondrionSequence analysisAdd
BLAST
Chaini26 – 692667Protein MTO1 homolog, mitochondrialPRO_0000042691Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000018776.

Structurei

3D structure databases

ProteinModelPortaliQ5RB71.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG2311. Eukaryota.
COG0445. LUCA.
HOVERGENiHBG031719.
InParanoidiQ5RB71.
KOiK03495.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5RB71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFYFRGCGRW VAASFTKLQF PLARLSSDST APRTPHFDVI VIGGGHAGTE
60 70 80 90 100
AATAAARCGS RTLLLTHRVD TIGQMSCNPS FGGIGKGHLM REVDALDGLC
110 120 130 140 150
SRICDQSGVH YKVLNRRKGP AVWGLRAQID RKLYKQNMQK EILNTPLLTV
160 170 180 190 200
QEGAVEDLIL TEPEPEHTGK CRVSGVVLVD GSTVYAESVI LTTGTFLRGI
210 220 230 240 250
IVIGLETHPA GRLGDQPSIG LAQTLEKLGF VVGRLKTGTP PRIAKESINF
260 270 280 290 300
SILNKHTPDN PSIPFSFTNE TVWIKPEDQL PCYLTHTNPR VDEIVLKNLH
310 320 330 340 350
LNSHVKETTR GPRYCPSIES KVLRFPNRLH QVWLEPEGMD SDLIYPQGLS
360 370 380 390 400
MTLPAELQEK MITCIRGLEK AKVIQPGYGV QYDYLDPRQI TPSLETHLVQ
410 420 430 440 450
RLFFAGQING TTGYEEAAAQ GVIAGINASL RVSRKPPFVV SRTEGYIGVL
460 470 480 490 500
IDDLTTLGTS EPYRMFTSRV EFRLSLRPDN ADSRLTLRGY KDAGCVSQQR
510 520 530 540 550
YERACWMKSS LEEGISVLKS IEFSSSKWKK LIPEASISTS RSLPVRALDV
560 570 580 590 600
LKYEEVDMDS LAKAVPEPLK KYTKCRELAE RLKIEATYES VLFHQLQEIK
610 620 630 640 650
GVQQDEALQL PKDLDYLTIR DVSLSHEVRE KLHFSRPQTI GAASRIPGVT
660 670 680 690
PAAIINLLRF VKTTQRRQAA MNESSKTDQY LCDADRLRER EL
Length:692
Mass (Da):77,244
Last modified:December 21, 2004 - v1
Checksum:i35595CC6B2FA2D6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR858783 mRNA. Translation: CAH90989.1.
RefSeqiNP_001128989.1. NM_001135517.1.
UniGeneiPab.19786.

Genome annotation databases

GeneIDi100190829.
KEGGipon:100190829.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR858783 mRNA. Translation: CAH90989.1.
RefSeqiNP_001128989.1. NM_001135517.1.
UniGeneiPab.19786.

3D structure databases

ProteinModelPortaliQ5RB71.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000018776.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100190829.
KEGGipon:100190829.

Organism-specific databases

CTDi25821.

Phylogenomic databases

eggNOGiKOG2311. Eukaryota.
COG0445. LUCA.
HOVERGENiHBG031719.
InParanoidiQ5RB71.
KOiK03495.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
[Graphical view]
PfamiPF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiPS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMTO1_PONAB
AccessioniPrimary (citable) accession number: Q5RB71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: December 21, 2004
Last modified: January 20, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.