Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5R7B0

- RPP29_PONAB

UniProt

Q5R7B0 - RPP29_PONAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ribonuclease P protein subunit p29

Gene

POP4

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P (By similarity).By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. RNA binding Source: InterPro

GO - Biological processi

  1. mRNA cleavage Source: InterPro
  2. rRNA processing Source: InterPro
  3. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p29 (EC:3.1.26.5)
Gene namesi
Name:POP4
Synonyms:RPP29
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
ProteomesiUP000001595: Chromosome 19

Subcellular locationi

Nucleusnucleolus By similarity

GO - Cellular componenti

  1. nucleolar ribonuclease P complex Source: InterPro
  2. ribonuclease MRP complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 220220Ribonuclease P protein subunit p29PRO_0000128420Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei10 – 101PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ5R7B0.

Interactioni

Subunit structurei

Component of nuclear RNase P and RNase MRP ribonucleoproteins. RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40. RNase MRP consists of an RNA moiety and at least 9 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38, RPP40, POP5 and RPP21. Interacts with RPP25 and POP5 (By similarity).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ5R7B0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi65 – 7410Poly-Lys

Sequence similaritiesi

Phylogenomic databases

GeneTreeiENSGT00390000010067.
HOVERGENiHBG002676.
InParanoidiQ5R7B0.
KOiK03538.
OMAiMSQQACE.
OrthoDBiEOG786H4B.
TreeFamiTF313883.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
InterProiIPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
PIRSFiPIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTiSM00538. POP4. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5R7B0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKSVIYHALS QKEANDSDVQ PSGAQRAEAF VRAFLKRSTP RMSPQAREDQ
60 70 80 90 100
LQRKAVVLEY FTRHKRKEKK KKAKGLSARQ RRELRLFDIK PEQQRYSLFL
110 120 130 140 150
PLHELWKQYI RDLCNGLKPD TQPQMIQAKL LKADLHGAII SVTKSKCPSY
160 170 180 190 200
VGITGILLQE TKHIFKIITK EDRLKVIPKL NCVFTVEIDG FISYIYGSKF
210 220
QLRSSERSAK KFKAKGTIDL
Length:220
Mass (Da):25,464
Last modified:December 21, 2004 - v1
Checksum:iCFD1861563DD648F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR860208 mRNA. Translation: CAH92350.1.
RefSeqiNP_001126383.1. NM_001132911.1.
UniGeneiPab.9084.

Genome annotation databases

EnsembliENSPPYT00000011409; ENSPPYP00000010980; ENSPPYG00000009805.
GeneIDi100173364.
KEGGipon:100173364.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR860208 mRNA. Translation: CAH92350.1 .
RefSeqi NP_001126383.1. NM_001132911.1.
UniGenei Pab.9084.

3D structure databases

ProteinModelPortali Q5R7B0.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q5R7B0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSPPYT00000011409 ; ENSPPYP00000010980 ; ENSPPYG00000009805 .
GeneIDi 100173364.
KEGGi pon:100173364.

Organism-specific databases

CTDi 10775.

Phylogenomic databases

GeneTreei ENSGT00390000010067.
HOVERGENi HBG002676.
InParanoidi Q5R7B0.
KOi K03538.
OMAi MSQQACE.
OrthoDBi EOG786H4B.
TreeFami TF313883.

Family and domain databases

Gene3Di 2.30.30.210. 1 hit.
InterProi IPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR023534. Rof/RNase_P-like.
[Graphical view ]
Pfami PF01868. UPF0086. 1 hit.
[Graphical view ]
PIRSFi PIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTi SM00538. POP4. 1 hit.
[Graphical view ]
SUPFAMi SSF101744. SSF101744. 1 hit.
ProtoNeti Search...

Publicationsi

  1. The German cDNA consortium
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.

Entry informationi

Entry nameiRPP29_PONAB
AccessioniPrimary (citable) accession number: Q5R7B0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: December 21, 2004
Last modified: October 1, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3