Glycerol-3-phosphate dehydrogenase 1-like protein - Pongo abelii (Sumatran orangutan)

Contribute

Read comments (1) or add your own

Reviewed, UniProtKB/Swiss-Prot Q5R5V3 (GPD1L_PONAB)

Last modified June 16, 2009. Version 30. History...

Clusters with 100%, 90%, 50% identity |

Documents (1) |

Third-party data |

Customize display

text xml rdf/xml gff fasta

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
Glycerol-3-phosphate dehydrogenase 1-like protein
EC=1.1.1.8

Gene names

Name:

GPD1L

Organism

Pongo abelii (Sumatran orangutan)

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pongo

Protein attributes

Sequence length	351 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Catalytic activity	sn-glycerol 3-phosphate + NAD⁺ = glycerone phosphate + NADH.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate catabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	glycerol-3-phosphate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular function	NAD or NADH binding Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: EC protein homodimerization activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

351

Glycerol-3-phosphate dehydrogenase 1-like protein

PRO_0000286513

Regions

Nucleotide binding

6

NAD By similarity

Region

2

Substrate binding By similarity

Sites

Active site

1

Proton acceptor By similarity

Binding site

1

NAD By similarity

Binding site

1

NAD By similarity

Binding site

1

Substrate By similarity

Binding site

1

NAD; via amide nitrogen By similarity

Binding site

1

NAD By similarity

Binding site

1

NAD; via amide nitrogen By similarity

Binding site

1

NAD By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q5R5V3-1 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: 74C273D429C8F30D
Show »

351

38,329

        10         20         30         40         50         60 
MAAAPLKVCI VGSGNWGSAV AKIIGNNVKK LQKFASTVKM WVFEETVNGR KLTDIINNDH 

        70         80         90        100        110        120 
ENVKYLPGHK LPENVVAISN LSEAVQDADL LVFVIPHQFI HRICDEITGR VPKKALGITL 

       130        140        150        160        170        180 
IKGIDEGPEG LKLISDIIRE KMGIDISVLM GANIANEVAA EKFCETTIGS KVMENGLLFK 

       190        200        210        220        230        240 
ELLQTPNFRI TVVDDADTVE LCGALKNIVA VGAGFCDGLR CGDNTKAAVI RLGLMEMIAF 

       250        260        270        280        290        300 
ARIFCKGQVS TATFLESCGV ADLITTCYGG RNRRVAEAFA RTGKTIEELE KEMLNGQKLQ 

       310        320        330        340        350 
GPQTSAEVYR ILKQKGLLDK FPLFTAVYQI CYESRPVQGM LSCLQSHPEH T

References

[1]	The German cDNA consortium Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain cortex.

Cross-references

Sequence databases
	CR860749 mRNA. Translation: CAH92863.1.
RefSeq	NP_001126675.1.
UniGene	Pab.18106
3D structure databases
SMR	Q5R5V3. Positions 4-346.
ModBase	Search...
Genome annotation databases
GeneID	100173675.
Phylogenomic databases
HOVERGEN	Q5R5V3.
Enzyme and pathway databases
BRENDA	1.1.1.8. 269192.
Family and domain databases
InterPro	IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006168. NAD-dep_Gly3P_DH. IPR017751. NAD-dep_Gly3P_DH_euk. IPR011128. NAD-dep_Gly3P_DH_N. IPR006109. NAD_Gly3P_DH_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
PANTHER	PTHR11728. NAD_Gly3P_DH. 1 hit.
Pfam	PF07479. NAD_Gly3P_dh_C. 1 hit. PF01210. NAD_Gly3P_dh_N. 1 hit. [Graphical view]
PIRSF	PIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTS	PR00077. GPDHDRGNASE.
ProDom	PD001278. NAD_Gly3P_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR03376. glycerol3P_DH. 1 hit.
PROSITE	PS00957. NAD_G3PDH. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPD1L_PONAB

Accession

Primary (citable) accession number: Q5R5V3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 15, 2007
Last sequence update:	December 21, 2004
Last modified:	June 16, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents