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Q5R5V2

- LAMP5_PONAB

UniProt

Q5R5V2 - LAMP5_PONAB

Protein

Lysosome-associated membrane glycoprotein 5

Gene

LAMP5

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Lysosome-associated membrane glycoprotein 5
    Alternative name(s):
    Brain and dendritic cell-associated LAMP
    Brain-associated LAMP-like protein
    Short name:
    BAD-LAMP
    Lysosome-associated membrane protein 5
    Short name:
    LAMP-5
    Gene namesi
    Name:LAMP5
    OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
    Taxonomic identifieri9601 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
    ProteomesiUP000001595: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasmic vesicle membrane Source: UniProtKB
    2. dendrite membrane Source: UniProtKB
    3. early endosome membrane Source: UniProtKB
    4. endoplasmic reticulum-Golgi intermediate compartment membrane Source: UniProtKB
    5. endosome membrane Source: UniProtKB
    6. growth cone membrane Source: UniProtKB
    7. plasma membrane Source: UniProtKB
    8. recycling endosome membrane Source: UniProtKB

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2929Sequence AnalysisAdd
    BLAST
    Chaini30 – 223194Lysosome-associated membrane glycoprotein 5PRO_0000042643Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi35 – 351N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi53 – 531N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi127 – 1271N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Glycosylated.By similarity

    Keywords - PTMi

    Glycoprotein

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LAMP family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    HOVERGENiHBG051186.
    InParanoidiQ5R5V2.

    Family and domain databases

    InterProiIPR002000. Lysosome-assoc_membr_glycop.
    [Graphical view]
    PANTHERiPTHR11506. PTHR11506. 1 hit.
    PfamiPF01299. Lamp. 1 hit.
    [Graphical view]
    PROSITEiPS00310. LAMP_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q5R5V2-1 [UniParc]FASTAAdd to Basket

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    MDLQGRAVPS VDRLRVLLML FHTMAQIMAE QEVENLSGLS TNPEKDIFVV    50
    RENGTTCLMA EFAAKFIVPY DVWASNYVDL ITEQADIALT RGAEVKGRCG 100
    HSESELQVFW VDRAYALKML FVKESHNMSK GPEETWRLSK VQFVYDSSEK 150
    THFKDAVSAG KHTANSHHLS ALVTPAGKSY ECQAQQTISL ASSDPQKIVT 200
    MILSAVHIQP FDIISDFVFS EGN 223
    Length:223
    Mass (Da):24,888
    Last modified:December 21, 2004 - v1
    Checksum:i8A5384997DE621CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR860751 mRNA. Translation: CAH92864.1.
    RefSeqiNP_001126676.1. NM_001133204.1.
    UniGeneiPab.2703.

    Genome annotation databases

    GeneIDi100173676.
    KEGGipon:100173676.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR860751 mRNA. Translation: CAH92864.1 .
    RefSeqi NP_001126676.1. NM_001133204.1.
    UniGenei Pab.2703.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 100173676.
    KEGGi pon:100173676.

    Organism-specific databases

    CTDi 24141.

    Phylogenomic databases

    HOVERGENi HBG051186.
    InParanoidi Q5R5V2.

    Family and domain databases

    InterProi IPR002000. Lysosome-assoc_membr_glycop.
    [Graphical view ]
    PANTHERi PTHR11506. PTHR11506. 1 hit.
    Pfami PF01299. Lamp. 1 hit.
    [Graphical view ]
    PROSITEi PS00310. LAMP_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. The German cDNA consortium
      Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain cortex.

    Entry informationi

    Entry nameiLAMP5_PONAB
    AccessioniPrimary (citable) accession number: Q5R5V2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 25, 2005
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3