Q5R348 (Q5R348_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P-selectin Ensembl ENSP00000399368

Gene names

Name:

SELP Ensembl ENSP00000399368

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000399368

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	753 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Contains 1 C-type lectin domain. SAAS SAAS001304
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000399368

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS016186 Repeat SAAS SAAS016186 Sushi SAAS SAAS000436
Ligand	Lectin SAAS SAAS016186
PTM	Disulfide bond SAAS SAAS016186
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA membrane Inferred from electronic annotation. Source: InterPro nucleus Inferred from direct assay. Source: HPA
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSP00000399368

Sequences

	Sequence		Length	Mass (Da)
	Q5R348 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 4E65D2B19E2C116E	FASTA	753	82,199
	10 20 30 40 50 60 VVFGISQLLC FSALISELTN QKEVAAWTYH YSTKAYSWNI SRKYCQNRYT DLVAIQNKNE 70 80 90 100 110 120 IDYLNKVLPY YSSYYWIGIR KNNKTWTWVG TKKALTNEAE NWADNEPNNK RNNEDCVEIY 130 140 150 160 170 180 IKSPSAPGKW NDEHCLKKKH ALCYTASCQD MSCSKQGECL ETIGNYTCSC YPGFYGPECE 190 200 210 220 230 240 YVRECGELEL PQHVLMNCSH PLGNFSFNSQ CSFHCTDGYQ VNGPSKLECL ASGIWTNKPP 250 260 270 280 290 300 QCLAAQCPPL KIPERGNMTC LHSAKAFQHQ SSCSFSCEEG FALVGPEVVQ CTASGVWTAP 310 320 330 340 350 360 APVCKAISCE PLESPVHGSM DCSPSLRAFQ YDTNCSFRCA EGFMLRGADI VRCDNLGQWT 370 380 390 400 410 420 APAPVCQALQ CQDLPVPNEA RVNCSHPFGA FRYQSVCSFT CNEGLLLVGA SVLQCLATGN 430 440 450 460 470 480 WNSVPPECQA IPCTPLLSPQ NGTMTCVQPL GSSSYKSTCQ FICDEGYSLS GPERLDCTRS 490 500 510 520 530 540 GRWTDSPPMC EAIKCPELFA PEQGSLDCSD TRGEFNVGST CHFSCDNGFK LEGPNNVECT 550 560 570 580 590 600 TSGRWSATPP TCKGIASLPT PGVQCPALTT PGQGTMYCRH HPGTFGFNTT CYFGCNAGFT 610 620 630 640 650 660 LIGDSTLSCR PSGQWTAVTP ACRAVKCSEL HVNKPIAMNC SNLWGNFSYG SICSFHCLEG 670 680 690 700 710 720 QLLNGSAQTA CQENGHWSTT VPTCQAGPLT IQEALTYFGG AVASTIGLIM GGTLLALLRK 730 740 750 RFRQKDDGKC PLNPHSHLGT YGVFTNAAFD PSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL022146 Genomic DNA. No translation available. Z99572 Genomic DNA. No translation available.
3D structure databases
SMR	Q5R348. Positions 27-688.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000458599; ENSP00000399368; ENSG00000174175.
Organism-specific databases
HGNC	HGNC:10721. SELP.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000236254.
HOVERGEN	HBG052375.
Gene expression databases
ArrayExpress	Q5R348.
Family and domain databases
Gene3D	3.10.100.10. 1 hit.
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR018378. C-type_lectin_CS. IPR016187. C-type_lectin_fold. IPR000742. EG-like_dom. IPR013032. EGF-like_CS. IPR002396. Selectin_superfamily. IPR000436. Sushi_SCR_CCP. [Graphical view]
Pfam	PF00059. Lectin_C. 1 hit. PF00084. Sushi. 8 hits. [Graphical view]
PRINTS	PR00343. SELECTIN.
SMART	SM00032. CCP. 8 hits. SM00034. CLECT. 1 hit. SM00181. EGF. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit. SSF57535. Complement_control_module. 8 hits.
PROSITE	PS00615. C_TYPE_LECTIN_1. 1 hit. PS50041. C_TYPE_LECTIN_2. 1 hit. PS00022. EGF_1. 1 hit. PS01186. EGF_2. 1 hit. PS50026. EGF_3. 1 hit. PS50923. SUSHI. 8 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	35539468.

Entry information

Entry name

Q5R348_HUMAN

Accession

Primary (citable) accession number: Q5R348

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	May 29, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.