Q5R341 (Q5R341_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P-selectin Ensembl ENSP00000356768 Ensembl ENSP00000356760

Submitted name:
Selectin P (Granule membrane protein 140kDa, antigen CD62), isoform CRA_a EMBL EAW90850.1

Gene names

Name:	SELP EMBL EAW90850.1 Ensembl ENSP00000356768 Ensembl ENSP00000356760
ORF Names:	hCG_38007 EMBL EAW90850.1

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000356768

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	768 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C-type lectin domain. SAAS SAAS001304

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS000436 Repeat SAAS SAAS001304 Sushi SAAS SAAS000436
Ligand	Lectin SAAS SAAS001304 EMBL EAW90850.1
PTM	Disulfide bond SAAS SAAS000436
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA membrane Inferred from electronic annotation. Source: InterPro nucleus Inferred from direct assay. Source: HPA
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5R341 [UniParc]. Last modified February 5, 2008. Version 1. Checksum: 2CC77FDC30CCDF4A	FASTA	768	84,036
	10 20 30 40 50 60 MANCQIAILY QRFQRVVFGI SQLLCFSALI SELTNQKEVA AWTYHYSTKA YSWNISRKYC 70 80 90 100 110 120 QNRYTDLVAI QNKNEIDYLN KVLPYYSSYY WIGIRKNNKT WTWVGTKKAL TNEAENWADN 130 140 150 160 170 180 EPNNKRNNED CVEIYIKSPS APGKWNDEHC LKKKHALCYT ASCQDMSCSK QGECLETIGN 190 200 210 220 230 240 YTCSCYPGFY GPECEYVREC GELELPQHVL MNCSHPLGNF SFNSQCSFHC TDGYQVNGPS 250 260 270 280 290 300 KLECLASGIW TNKPPQCLAA QCPPLKIPER GNMTCLHSAK AFQHQSSCSF SCEEGFALVG 310 320 330 340 350 360 PEVVQCTASG VWTAPAPVCK AISCEPLESP VHGSMDCSPS LRAFQYDTNC SFRCAEGFML 370 380 390 400 410 420 RGADIVRCDN LGQWTAPAPV CQALQCQDLP VPNEARVNCS HPFGAFRYQS VCSFTCNEGL 430 440 450 460 470 480 LLVGASVLQC LATGNWNSVP PECQAIPCTP LLSPQNGTMT CVQPLGSSSY KSTCQFICDE 490 500 510 520 530 540 GYSLSGPERL DCTRSGRWTD SPPMCEAIKC PELFAPEQGS LDCSDTRGEF NVGSTCHFSC 550 560 570 580 590 600 DNGFKLEGPN NVECTTSGRW SATPPTCKGI ASLPTPGVQC PALTTPGQGT MYCRHHPGTF 610 620 630 640 650 660 GFNTTCYFGC NAGFTLIGDS TLSCRPSGQW TAVTPACRAV KCSELHVNKP IAMNCSNLWG 670 680 690 700 710 720 NFSYGSICSF HCLEGQLLNG SAQTACQENG HWSTTVPTCQ AGPLTIQEAL TYFGGAVAST 730 740 750 760 IGLIMGGTLL ALLRKRFRQK DDGKCPLNPH SHLGTYGVFT NAAFDPSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL022146 Genomic DNA. No translation available. Z99572 Genomic DNA. No translation available. CH471067 Genomic DNA. Translation: EAW90850.1.
IPI	IPI00644144.
UniGene	Hs.73800.
3D structure databases
SMR	Q5R341. Positions 42-702.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000367786; ENSP00000356760; ENSG00000174175. ENST00000367794; ENSP00000356768; ENSG00000174175.
Organism-specific databases
HGNC	HGNC:10721. SELP.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000236254.
HOVERGEN	HBG052375.
Gene expression databases
ArrayExpress	Q5R341.
Family and domain databases
Gene3D	3.10.100.10. 1 hit.
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR018378. C-type_lectin_CS. IPR016187. C-type_lectin_fold. IPR000742. EG-like_dom. IPR013032. EGF-like_CS. IPR002396. Selectin_superfamily. IPR000436. Sushi_SCR_CCP. [Graphical view]
Pfam	PF00059. Lectin_C. 1 hit. PF00084. Sushi. 8 hits. [Graphical view]
PRINTS	PR00343. SELECTIN.
SMART	SM00032. CCP. 8 hits. SM00034. CLECT. 1 hit. SM00181. EGF. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit. SSF57535. Complement_control_module. 8 hits.
PROSITE	PS00615. C_TYPE_LECTIN_1. 1 hit. PS50041. C_TYPE_LECTIN_2. 1 hit. PS00022. EGF_1. 1 hit. PS01186. EGF_2. 1 hit. PS50026. EGF_3. 1 hit. PS50923. SUSHI. 8 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	35539464.

Entry information

Entry name

Q5R341_HUMAN

Accession

Primary (citable) accession number: Q5R341

Entry history

Integrated into UniProtKB/TrEMBL:	February 5, 2008
Last sequence update:	February 5, 2008
Last modified:	May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.