Q5R0P0 (Q5R0P0_IDILO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyruvate dehydrogenase (Dihydrolipoyltransacetylase component, E2) EMBL AAV81302.1

Gene names

Name:	aceF EMBL AAV81302.1
Ordered Locus Names:	IL0459 EMBL AAV81302.1

Organism

Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) [Complete proteome] [HAMAP] EMBL AAV81302.1

Taxonomic identifier

283942 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Idiomarinaceae › Idiomarina › Idiomarina loihiensis

Protein attributes

Sequence length	591 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU003423 Contains 2 lipoyl-binding domains. RuleBase RU000447

Ontologies

Keywords
Domain	Lipoyl SAAS SAAS003016 RuleBase RU000447
Ligand	Pyruvate EMBL AAV81302.1
Molecular function	Acyltransferase RuleBase RU003765 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: InterPro
Cellular_component	pyruvate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	dihydrolipoyllysine-residue acetyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5R0P0 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: E629A0E5DB153606	FASTA	591	63,846
	10 20 30 40 50 60 MADQIELKVP DVGGEEVEVI EILVSEGDTV EQEDGIVTVE SDKASMDIPA SSGGKITELK 70 80 90 100 110 120 VKVGDTISEG DVLAMIEASG GADESDESDS EEEAEDKTDD KADEEATKDK AEESEDKQEE 130 140 150 160 170 180 EKDEDSEPEK KSSGGGSKVI DVEVPDIGDE EDVEIIEILV SKGDSVSAED GLITLETDKA 190 200 210 220 230 240 TMDVPCPEDG EIEEMLVKVG DKVSQGSVIA KLKVSGGADD SEAEEKDSAK EEKSESNKES 250 260 270 280 290 300 DKDSGKKSED KDQKKDSGSS VKPSSERQPP VPDHPSQRSD RKEGILHASP AVRRVAREFG 310 320 330 340 350 360 VDLSQVKGSG PKDRILKEDV QEFVKYELSR PKAVAGATGQ GGGGLQVIDP PKVDFSKFGE 370 380 390 400 410 420 VEEVQLSRIQ RKSGPNLHRN WVTIPHVTQF DEADITELEN FRKSENEVAK KKDLGFKITP 430 440 450 460 470 480 LVFILKACAK GLREFPTFNS SLSESGESLY MKKYVNIGVA VDTPNGLVVP VIRDVDKKGI 490 500 510 520 530 540 YELSEELVEI SSKARDGKLK ATDMQGGCFS ISSLGGIGGT AFTPIVNAPD VAILGVSRNE 550 560 570 580 590 MKPKWNGKEF EPRLTLPLSL SYDHRVIDGA EAARFTAYLS GVLGDIRKLV L

References

[1]

"Genome sequence of the deep-sea gamma-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy." Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y., Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S., Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S., Campbell S., Denery J. , Aizawa S., Shibata S., Malahoff A., Alam M. Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-735 / DSM 15497 / L2-TR.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017340 Genomic DNA. Translation: AAV81302.1.
RefSeq	YP_154851.1. NC_006512.1.
3D structure databases
ProteinModelPortal	Q5R0P0.
SMR	Q5R0P0. Positions 5-82, 351-591.
ModBase	Search...
Protein-protein interaction databases
STRING	283942.IL0459.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAV81302; AAV81302; IL0459.
GeneID	3173448.
KEGG	ilo:IL0459.
PATRIC	22138939. VBIIdiLoi21852_0461.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000281562.
KO	K00627.
OMA	PLSMSYD.
ProtClustDB	PRK11855.
Enzyme and pathway databases
BioCyc	ILOI283942:GI0U-501-MONOMER.
Family and domain databases
Gene3D	3.30.559.10. 1 hit. 4.10.320.10. 1 hit.
InterPro	IPR003016. 2-oxoA_DH_lipoyl-BS. IPR001078. 2-oxoacid_DH_actylTfrase. IPR006256. AcTrfase_Pyrv_DH_cplx. IPR000089. Biotin_lipoyl. IPR023213. CAT-like_dom. IPR004167. E3-bd. IPR011053. Single_hybrid_motif. [Graphical view]
Pfam	PF00198. 2-oxoacid_dh. 1 hit. PF00364. Biotin_lipoyl. 2 hits. PF02817. E3_binding. 1 hit. [Graphical view]
SUPFAM	SSF47005. E3_bd. 1 hit. SSF51230. Hybrid_motif. 2 hits.
TIGRFAMs	TIGR01348. PDHac_trf_long. 1 hit.
PROSITE	PS50968. BIOTINYL_LIPOYL. 2 hits. PS00189. LIPOYL. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5R0P0_IDILO

Accession

Primary (citable) accession number: Q5R0P0

Entry history

Integrated into UniProtKB/TrEMBL:	January 4, 2005
Last sequence update:	January 4, 2005
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)