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Q5R0M2 (FTSW_IDILO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipid II flippase FtsW
Alternative name(s):
Cell division protein FtsW
Gene names
Name:ftsW
Ordered Locus Names:IL0435
OrganismIdiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) [Complete proteome] [HAMAP]
Taxonomic identifier283942 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane By similarity. HAMAP-Rule MF_00913

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity. Note: Localizes to the division septum By similarity. HAMAP-Rule MF_00913

Sequence similarities

Belongs to the SEDS family. FtsW subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 409409Lipid II flippase FtsW HAMAP-Rule MF_00913
PRO_0000415192

Regions

Transmembrane42 – 6221Helical; Potential
Transmembrane72 – 9221Helical; Potential
Transmembrane108 – 12821Helical; Potential
Transmembrane135 – 15521Helical; Potential
Transmembrane178 – 19821Helical; Potential
Transmembrane213 – 23321Helical; Potential
Transmembrane303 – 32321Helical; Potential
Transmembrane337 – 35721Helical; Potential
Transmembrane368 – 38821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q5R0M2 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: E1CF213E8873C40D

FASTA40945,093
        10         20         30         40         50         60 
MSTVREEQLN LEIPASDVGS RWQKLINWFQ PKASQPLYDR MLFTLAMALL AFGFVMVTSA 

        70         80         90        100        110        120 
SLPTADRLTG NPFHFAIRHG IYILISLAVM LATLRVPANS WNQQSGKLLL LGLIMLLMVL 

       130        140        150        160        170        180 
VVGYEVNGAQ RWIKVGPITF QAAEVAKLFF CIYMASYLSR REDEVREATK GFIKPLALLF 

       190        200        210        220        230        240 
IAAVLLLMQP DFGTVVVLSA TTVAMLFLAG ARLWQFFAVF ITCVLALILL IIVEPYRMQR 

       250        260        270        280        290        300 
LLTFLEPEKD PFGAGYQLMQ SLIAFGQGHF SGAGLGNSIQ KLQYLPEAHT DFIMAVVAEE 

       310        320        330        340        350        360 
LGFLGVLAVI ATVLMLVWRA LIIGRRCLMQ EQRYGGYLAY GIGIWFSIQA FVNIGVASGA 

       370        380        390        400 
LPTKGLTLPL VSYGGNSLII SALAVGLLLR IDHERRMLGR KVAPRGGAE 

« Hide

References

[1]"Genome sequence of the deep-sea gamma-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy."
Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y., Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S., Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S., Campbell S., Denery J. expand/collapse author list , Aizawa S., Shibata S., Malahoff A., Alam M.
Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-735 / DSM 15497 / L2-TR.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017340 Genomic DNA. Translation: AAV81278.1.
RefSeqYP_154827.1. NC_006512.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING283942.IL0435.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAV81278; AAV81278; IL0435.
GeneID3171953.
KEGGilo:IL0435.
PATRIC22138891. VBIIdiLoi21852_0437.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000282689.
KOK03588.
OMAFIVLLPM.
OrthoDBEOG68M4JQ.

Enzyme and pathway databases

BioCycILOI283942:GI0U-438-MONOMER.

Family and domain databases

HAMAPMF_00913. FtsW_proteobact.
InterProIPR018365. Cell_cycle_FtsW-rel_CS.
IPR001182. Cell_cycle_FtsW/RodA.
IPR013437. Cell_div_FtsW.
[Graphical view]
PfamPF01098. FTSW_RODA_SPOVE. 1 hit.
[Graphical view]
TIGRFAMsTIGR02614. ftsW. 1 hit.
PROSITEPS00428. FTSW_RODA_SPOVE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFTSW_IDILO
AccessionPrimary (citable) accession number: Q5R0M2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 25, 2012
Last sequence update: January 4, 2005
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families