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Q5QZT7

- Q5QZT7_IDILO

UniProt

Q5QZT7 - Q5QZT7_IDILO

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Protein
Submitted name:

Monomeric isocitrate dehydrogenase

Gene
IL1433
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei147 – 1471Substrate By similarityUniRule annotation
Sitei256 – 2561Critical for catalysis By similarityUniRule annotation
Metal bindingi351 – 3511Magnesium or manganese By similarityUniRule annotation
Sitei421 – 4211Critical for catalysis By similarityUniRule annotation
Binding sitei548 – 5481Substrate By similarityUniRule annotation
Metal bindingi549 – 5491Magnesium or manganese By similarityUniRule annotation
Metal bindingi553 – 5531Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciILOI283942:GI0U-1443-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Monomeric isocitrate dehydrogenaseImported
Gene namesi
Ordered Locus Names:IL1433Imported
OrganismiIdiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)Imported
Taxonomic identifieri283942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina
ProteomesiUP000001171: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi283942.IL1433.

Structurei

3D structure databases

ProteinModelPortaliQ5QZT7.
SMRiQ5QZT7. Positions 7-741.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni134 – 1418Substrate binding By similarityUniRule annotation

Phylogenomic databases

HOGENOMiHOG000240860.
KOiK00031.
OMAiRPSEVFN.
OrthoDBiEOG6DVJPP.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5QZT7-1 [UniParc]FASTAAdd to Basket

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MSTDKAKIIY TETDEAPRLA TYSFLPFIEA FTKAAGVSVE TRDISLAGRI    50
ISQFPEYLTE EQRQSDALAE LGEMAKTAEA NIIKLPNISA SIPQMTACIK 100
ELQNQGYKLP DYPFDPQTDE EKDVRSRYDK VKGSAVNPVL REGNSDRRAP 150
SAVKNYAKKH PHRMGEWSKD SKSHVAHMNE GDFYGSEKSV TSASEDTFKI 200
VFESNGEQKV LKESVPVLAG EVVDAATMSK KQLQAFFEKE TVAAKEQGVL 250
LSLHLKATMM KVSDPIMFGH AVRVFYKDVL EKHADLMKEI EFDPSNGIGD 300
LYSKLDKLTA EQRDAIEVDM NAVYAKQPEL AMVNSHKGIT NLHVPSDIII 350
DASMPAMIRD SGKMWDTNDS QQDAKAMIPD RSYAGVYQET IDFCRENGAF 400
DPATMGTVPN VGLMAQKAEE YGSHDKTFEI PANGVVKVFN KAGDVVFEHK 450
VEEGDIWRMC QVKDAPIRDW VKLAVNRSRL SGMPAVFWLD SNRAHDAQLI 500
KKVEEYLKEH DTDGLDIQIM APVEATRHTL QRVKEGKDTI SVTGNVLRDY 550
LTDLFPILEL GTSAKMLSIV PLMNGGGLFE TGAGGSAPKH VQQFVEENHL 600
RWDSLGEFLA LAASLEHLSR TFDNKRALVL ADSLDLATAK FLEENKSPSR 650
KVGEIDNRGS HFYLAMYWAE ALANQNEDAE LKERFSKLFE KLSGNEQAII 700
NELNEIQGVK VDIGGYYQPN TDKVSAAMRP CSVLNETLGS L 741
Length:741
Mass (Da):82,455
Last modified:January 4, 2005 - v1
Checksum:i9EA88DA0DD15246E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017340 Genomic DNA. Translation: AAV82273.1.
RefSeqiYP_155822.1. NC_006512.1.

Genome annotation databases

EnsemblBacteriaiAAV82273; AAV82273; IL1433.
GeneIDi3172011.
KEGGiilo:IL1433.
PATRICi22140945. VBIIdiLoi21852_1435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017340 Genomic DNA. Translation: AAV82273.1 .
RefSeqi YP_155822.1. NC_006512.1.

3D structure databases

ProteinModelPortali Q5QZT7.
SMRi Q5QZT7. Positions 7-741.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 283942.IL1433.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAV82273 ; AAV82273 ; IL1433 .
GeneIDi 3172011.
KEGGi ilo:IL1433.
PATRICi 22140945. VBIIdiLoi21852_1435.

Phylogenomic databases

HOGENOMi HOG000240860.
KOi K00031.
OMAi RPSEVFN.
OrthoDBi EOG6DVJPP.

Enzyme and pathway databases

BioCyci ILOI283942:GI0U-1443-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-735 / DSM 15497 / L2-TR.

Entry informationi

Entry nameiQ5QZT7_IDILO
AccessioniPrimary (citable) accession number: Q5QZT7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: July 9, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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