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Q5QZT7

- Q5QZT7_IDILO

UniProt

Q5QZT7 - Q5QZT7_IDILO

Protein
Submitted name:

Monomeric isocitrate dehydrogenase

Gene

IL1433

Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 57 (01 Oct 2014)
      Sequence version 1 (04 Jan 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471Substrate
    Sitei256 – 2561Critical for catalysisUniRule annotation
    Metal bindingi351 – 3511Magnesium or manganeseUniRule annotation
    Sitei421 – 4211Critical for catalysisUniRule annotation
    Binding sitei548 – 5481SubstrateUniRule annotation
    Metal bindingi549 – 5491Magnesium or manganeseUniRule annotation
    Metal bindingi553 – 5531Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciILOI283942:GI0U-1443-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Monomeric isocitrate dehydrogenaseImported
    Gene namesi
    Ordered Locus Names:IL1433Imported
    OrganismiIdiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)Imported
    Taxonomic identifieri283942 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina
    ProteomesiUP000001171: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi283942.IL1433.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5QZT7.
    SMRiQ5QZT7. Positions 7-741.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate binding

    Phylogenomic databases

    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiRPSEVFN.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5QZT7-1 [UniParc]FASTAAdd to Basket

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    MSTDKAKIIY TETDEAPRLA TYSFLPFIEA FTKAAGVSVE TRDISLAGRI    50
    ISQFPEYLTE EQRQSDALAE LGEMAKTAEA NIIKLPNISA SIPQMTACIK 100
    ELQNQGYKLP DYPFDPQTDE EKDVRSRYDK VKGSAVNPVL REGNSDRRAP 150
    SAVKNYAKKH PHRMGEWSKD SKSHVAHMNE GDFYGSEKSV TSASEDTFKI 200
    VFESNGEQKV LKESVPVLAG EVVDAATMSK KQLQAFFEKE TVAAKEQGVL 250
    LSLHLKATMM KVSDPIMFGH AVRVFYKDVL EKHADLMKEI EFDPSNGIGD 300
    LYSKLDKLTA EQRDAIEVDM NAVYAKQPEL AMVNSHKGIT NLHVPSDIII 350
    DASMPAMIRD SGKMWDTNDS QQDAKAMIPD RSYAGVYQET IDFCRENGAF 400
    DPATMGTVPN VGLMAQKAEE YGSHDKTFEI PANGVVKVFN KAGDVVFEHK 450
    VEEGDIWRMC QVKDAPIRDW VKLAVNRSRL SGMPAVFWLD SNRAHDAQLI 500
    KKVEEYLKEH DTDGLDIQIM APVEATRHTL QRVKEGKDTI SVTGNVLRDY 550
    LTDLFPILEL GTSAKMLSIV PLMNGGGLFE TGAGGSAPKH VQQFVEENHL 600
    RWDSLGEFLA LAASLEHLSR TFDNKRALVL ADSLDLATAK FLEENKSPSR 650
    KVGEIDNRGS HFYLAMYWAE ALANQNEDAE LKERFSKLFE KLSGNEQAII 700
    NELNEIQGVK VDIGGYYQPN TDKVSAAMRP CSVLNETLGS L 741
    Length:741
    Mass (Da):82,455
    Last modified:January 4, 2005 - v1
    Checksum:i9EA88DA0DD15246E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017340 Genomic DNA. Translation: AAV82273.1.
    RefSeqiYP_155822.1. NC_006512.1.

    Genome annotation databases

    EnsemblBacteriaiAAV82273; AAV82273; IL1433.
    GeneIDi3172011.
    KEGGiilo:IL1433.
    PATRICi22140945. VBIIdiLoi21852_1435.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017340 Genomic DNA. Translation: AAV82273.1 .
    RefSeqi YP_155822.1. NC_006512.1.

    3D structure databases

    ProteinModelPortali Q5QZT7.
    SMRi Q5QZT7. Positions 7-741.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 283942.IL1433.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAV82273 ; AAV82273 ; IL1433 .
    GeneIDi 3172011.
    KEGGi ilo:IL1433.
    PATRICi 22140945. VBIIdiLoi21852_1435.

    Phylogenomic databases

    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi RPSEVFN.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci ILOI283942:GI0U-1443-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-735 / DSM 15497 / L2-TRImported.

    Entry informationi

    Entry nameiQ5QZT7_IDILO
    AccessioniPrimary (citable) accession number: Q5QZT7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 4, 2005
    Last sequence update: January 4, 2005
    Last modified: October 1, 2014
    This is version 57 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3