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Protein

Guanylate kinase

Gene

gmk

Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciILOI283942:G1G13-2458-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:IL2382
OrganismiIdiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Taxonomic identifieri283942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina
Proteomesi
  • UP000001171 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705491 – 210Guanylate kinaseAdd BLAST210

Interactioni

Protein-protein interaction databases

STRINGi283942.IL2382

Structurei

3D structure databases

ProteinModelPortaliQ5QYH9
SMRiQ5QYH9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 188Guanylate kinase-likeUniRule annotationAdd BLAST181

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5QYH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTASPVLGNL FIIAAPSGAG KSSLIRALLE KHPDQSMQVS VSSTTRAPRP
60 70 80 90 100
GEVQGVHYHF LSTEEFEQRI DAGEFYEWAR VFGNYYGTSR KVVESLLAEG
110 120 130 140 150
KDVFLDIDWQ GAQQVREHHP EVRSVFIVPP SLEILEERLR VRGQDSDEVI
160 170 180 190 200
AERMAKAQAE MSHYHEFDYL LVNDDFNNSL ASLEHIVLAQ RQKMPHQQIR
210
YSSVLKELLG
Length:210
Mass (Da):23,836
Last modified:January 4, 2005 - v1
Checksum:i9F136AB6DB91CFED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017340 Genomic DNA Translation: AAV83214.1
RefSeqiWP_011235608.1, NC_006512.1

Genome annotation databases

EnsemblBacteriaiAAV83214; AAV83214; IL2382
KEGGiilo:IL2382

Similar proteinsi

Entry informationi

Entry nameiKGUA_IDILO
AccessioniPrimary (citable) accession number: Q5QYH9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: January 4, 2005
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health