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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei67L-glutamineUniRule annotation1
Binding sitei212L-glutamineUniRule annotation1
Binding sitei231ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi35 – 37ATPUniRule annotation3
Nucleotide bindingi41 – 47ATPUniRule annotation7
Nucleotide bindingi261 – 262ATPUniRule annotation2
Nucleotide bindingi269 – 271ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:IL1478
OrganismiIdiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Taxonomic identifieri283942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina
Proteomesi
  • UP000001171 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000954921 – 561Glutamine--tRNA ligaseAdd BLAST561

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi283942.IL1478.

Structurei

3D structure databases

ProteinModelPortaliQ5QXQ2.
SMRiQ5QXQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi34 – 44"HIGH" regionUniRule annotationAdd BLAST11
Motifi268 – 272"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5QXQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADTDSRPSN FIRQIIDKDL ASGKHATVHT RFPPEPNGYL HIGHAKSIVL
60 70 80 90 100
NFGIAEDYNG TCNLRFDDTN PLKEKVDYVN SIKKDVEWLG YHWEGEPRYS
110 120 130 140 150
SNYFDQLHGF AVELIEKGLA YVDFSSQDKM REMRGTLKEP GVNSPYRDTS
160 170 180 190 200
VEENLKHFAD MTAGKHEEGT AALRAKIDMS SPFMCMRDPV IYRVRFVHHH
210 220 230 240 250
QTGDKWCVYP MYDFTHCISD ALEGITHSLC TLEFQDNRRL YDWVLDNISI
260 270 280 290 300
DCHPQQIEFS RLNLQYTVMS KRIINTLVDE NKVSGWDDPR IASIAGLRRR
310 320 330 340 350
GYTPDSVREF CRRIGVTKMD NQVEMSMLEA CIRDDLNVNA PRAMAVMDPV
360 370 380 390 400
KIVIENYPEG EQELLDAPNH PNDPEMGSRQ VTFSREIWIE REDFRESANK
410 420 430 440 450
KFKRLVLDKE VRLRNAYVIR ADRIETDDNG EIQTIYCHYD ADTLGKDPAD
460 470 480 490 500
GRKVKGVIHW VSAETAKAAE FRVYDRLFQV PNPAAEEDLF STLNPESLVI
510 520 530 540 550
KKGFVEANLA SAKLGENFQF ERLGYYCLDQ DAETEGRLIF NQTVGLRDSW
560
AKIEQEQTTG S
Length:561
Mass (Da):64,529
Last modified:January 4, 2005 - v1
Checksum:iE48E5B3DFE2AF8F2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017340 Genomic DNA. Translation: AAV82318.1.
RefSeqiWP_011234724.1. NC_006512.1.

Genome annotation databases

EnsemblBacteriaiAAV82318; AAV82318; IL1478.
KEGGiilo:IL1478.

Similar proteinsi

Entry informationi

Entry nameiSYQ_IDILO
AccessioniPrimary (citable) accession number: Q5QXQ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 4, 2005
Last modified: August 30, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families