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Reviewed, UniProtKB/Swiss-Prot Q5QXQ2 (SYQ_IDILO)

Last modified November 3, 2009. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Glutaminyl-tRNA synthetase
    EC=6.1.1.18
Alternative name(s):
    Glutamine--tRNA ligase
      Short name=GlnRS
Gene names
Name: glnS
Ordered Locus Names: IL1478
OrganismIdiomarina loihiensis [Complete proteome] [HAMAP]
Taxonomic identifier135577 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina

Protein attributes

Sequence length561 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP MF_00126

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 561561Glutaminyl-tRNA synthetase HAMAP MF_00126
PRO_1000095492

Regions

Motif34 – 4411"HIGH" region HAMAP MF_00126
Motif268 – 2725"KMSKS" region HAMAP MF_00126

Sites

Binding site2711ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5QXQ2-1 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: E48E5B3DFE2AF8F2

FASTA56164,529
        10         20         30         40         50         60 
MADTDSRPSN FIRQIIDKDL ASGKHATVHT RFPPEPNGYL HIGHAKSIVL NFGIAEDYNG 

        70         80         90        100        110        120 
TCNLRFDDTN PLKEKVDYVN SIKKDVEWLG YHWEGEPRYS SNYFDQLHGF AVELIEKGLA 

       130        140        150        160        170        180 
YVDFSSQDKM REMRGTLKEP GVNSPYRDTS VEENLKHFAD MTAGKHEEGT AALRAKIDMS 

       190        200        210        220        230        240 
SPFMCMRDPV IYRVRFVHHH QTGDKWCVYP MYDFTHCISD ALEGITHSLC TLEFQDNRRL 

       250        260        270        280        290        300 
YDWVLDNISI DCHPQQIEFS RLNLQYTVMS KRIINTLVDE NKVSGWDDPR IASIAGLRRR 

       310        320        330        340        350        360 
GYTPDSVREF CRRIGVTKMD NQVEMSMLEA CIRDDLNVNA PRAMAVMDPV KIVIENYPEG 

       370        380        390        400        410        420 
EQELLDAPNH PNDPEMGSRQ VTFSREIWIE REDFRESANK KFKRLVLDKE VRLRNAYVIR 

       430        440        450        460        470        480 
ADRIETDDNG EIQTIYCHYD ADTLGKDPAD GRKVKGVIHW VSAETAKAAE FRVYDRLFQV 

       490        500        510        520        530        540 
PNPAAEEDLF STLNPESLVI KKGFVEANLA SAKLGENFQF ERLGYYCLDQ DAETEGRLIF 

       550        560 
NQTVGLRDSW AKIEQEQTTG S 

« Hide

References

[1]"Genome sequence of the deep-sea gamma-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy."
Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y., Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S., Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S., Campbell S., Denery J. expand/collapse author list , Aizawa S., Shibata S., Malahoff A., Alam M.
Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004) [PubMed: 15596722] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L2-TR / ATCC BAA-735 / DSM 15497.

Cross-references

Sequence databases

AE017340 Genomic DNA. Translation: AAV82318.1.
RefSeqYP_155867.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3172053.
GenomeReviewsGene locus IL1478 in contig AE017340_GR.
KEGGilo:IL1478.
NMPDRfig|283942.3.peg.1928.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5QXQ2.
OMARMPTIAG.

Enzyme and pathway databases

BioCycILOI283942:IL1478-MON.

Family and domain databases

HAMAPMF_00126.
[Tree]
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth_Ic.
IPR000924. Glu/Gln-tRNA-synth_Ic.
IPR020061. Glu/Gln-tRNA-synth_Ic_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ic_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ic_codon-bd.
IPR020060. Glu/Gln-tRNA-synth_Ic_N.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
[Graphical view]
Gene3DG3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit.
G3DSA:2.40.240.10. Rbsml_L25/Gln-tRNA_synth_b-brl. 1 hit.
PANTHERPTHR10119:SF3. GlnS. 1 hit.
PTHR10119. Glu_tRNA-synt_1c. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_IDILO
AccessionPrimary (citable) accession number: Q5QXQ2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 4, 2005
Last modified: November 3, 2009
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents