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Reviewed, UniProtKB/Swiss-Prot Q5QXJ4 (HEM6_IDILO)

Last modified June 16, 2009. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: IL0023
OrganismIdiomarina loihiensis [Complete proteome] [HAMAP]
Taxonomic identifier135577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Idiomarinaceae › Idiomarina

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Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304Coproporphyrinogen-III oxidase, aerobic
PRO_0000109899

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Sequences

Sequence LengthMass (Da)Tools
Q5QXJ4-1 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: DB7F81B4B9B414AF

FASTA30435,113
        10         20         30         40         50         60 
MHNDYLKQVK SYLMSLQDAI CQQLAQADGE QSFQEDSWDR PGGGGGRSRI MKNGAVFEQG 

        70         80         90        100        110        120 
GVGFSHVYGE KMPASATAHR PELEGRDFNA CGVSLVMHPE NPMVPTVHMN VRFFIAQKEG 

       130        140        150        160        170        180 
EEPVWWFGGG FDLTPFYPFD QDIIEWHQQA KNALDSVDEK LYPEYKAWCD DYFFLKHRDE 

       190        200        210        220        230        240 
ARGVGGIFFD DLNDRSFDEC FSVIKAVGDA FTKAYLPIVE RRKNLAYTQQ QRDFQLYRRG 

       250        260        270        280        290        300 
RYVEFNLVWD RGTLFGLQTG GRTESILMSM PPLARWEYNW QAEPGSAEEQ LTEYYLKPRD 


WLSV

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References

[1]"Genome sequence of the deep-sea gamma-proteobacterium Idiomarina loihiensis reveals amino acid fermentation as a source of carbon and energy."
Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y., Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S., Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S., Campbell S., Denery J. expand/collapse author list , Aizawa S., Shibata S., Malahoff A., Alam M.
Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004) [PubMed: 15596722] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: L2-TR / ATCC BAA-735 / DSM 15497.

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Cross-references

Sequence databases

AE017340 Genomic DNA. Translation: AAV80867.1.
RefSeqYP_154416.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3173121.
GenomeReviewsGene locus IL0023 in contig AE017340_GR.
KEGGilo:IL0023.
NMPDRfig|283942.3.peg.73.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5QXJ4.
OMAQ5QXJ4. VKAYLLD.

Enzyme and pathway databases

BioCycILOI283942:IL0023-MON.
BRENDA1.3.3.3. 280818.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_IDILO
AccessionPrimary (citable) accession number: Q5QXJ4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: January 4, 2005
Last modified: June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents