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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:IL2460
OrganismiIdiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Taxonomic identifieri283942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesIdiomarinaceaeIdiomarina
Proteomesi
  • UP000001171 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420321 – 580Arginine--tRNA ligaseAdd BLAST580

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi283942.IL2460.

Structurei

3D structure databases

ProteinModelPortaliQ5QV46.
SMRiQ5QV46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi127 – 137"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5QV46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKEQLEQLLA EAIGQLKAQG TIPADHSVNI QLDRPRDKSH GDFATNLALM
60 70 80 90 100
LAKPAKSNPR QLAEAIVAAV PENSLLSKMD IAGPGFINFT ISQDQLKDQL
110 120 130 140 150
TAMLNSDSLN VDVAEESKTI VIDYSSPNLA KEMHVGHLRS AIIGDAVSRV
160 170 180 190 200
CEFLGHKVIR QNHVGDWGTQ FGMLLAYMEA LDNQSAEYEL SNLETFYKAA
210 220 230 240 250
KQRFDESEEF ADRARQLVVK LQSGDEYCLK LWNQFIDVSL SHCQDVYDRL
260 270 280 290 300
GVKLTRDDVM AESAYNDKLP GVIEHLREKG LLTEDQGAQC VFLEEYKGKE
310 320 330 340 350
GEPLPIIVQK KGGGYLYATT DLAAIEYRQK ELGGDHLMYF VDARQALHFD
360 370 380 390 400
QIFTLARKAG FVEGDIQLNH YGFGTVMGKD GKPYKSRDGG VTKLADLLDE
410 420 430 440 450
AERRALELLQ QKTTDLSEEQ QKRVAEVVGI SSVKYADLSK NRTSDYVFDW
460 470 480 490 500
NHMLTFEGNT APYLLYAFTR VNSIFDRLGD TAFDRNADII LSDERELALA
510 520 530 540 550
NQLVRFNEVL HQVQDKAMPH FLCGFLFDLA GRFSSFYEAC PILNQEDEAL
560 570 580
RNSRLKLSML TANVLKQGLE LLGIPTLEKM
Length:580
Mass (Da):65,143
Last modified:January 4, 2005 - v1
Checksum:iACC15126CB14E7C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017340 Genomic DNA. Translation: AAV83292.1.
RefSeqiWP_011235685.1. NC_006512.1.

Genome annotation databases

EnsemblBacteriaiAAV83292; AAV83292; IL2460.
KEGGiilo:IL2460.

Similar proteinsi

Entry informationi

Entry nameiSYR_IDILO
AccessioniPrimary (citable) accession number: Q5QV46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 4, 2005
Last modified: November 22, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families