Unreviewed, UniProtKB/TrEMBL Q5QNZ9 (Q5QNZ9_HUMAN)

Names and origin

Protein names

Submitted name:
    Poly (ADP-ribose) polymerase family, member 4 EMBL CAI12394.1

Gene names

Name:	PARP4 EMBL CAI12394.1
ORF Names:	RP11-169O17.2-001 EMBL CAI12394.1

Organism

Homo sapiens (Human) EMBL CAI12394.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1724 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 PARP catalytic domain. Spearmint SPM012317

Ontologies

Gene Ontology (GO)
Biological process	protein amino acid ADP-ribosylation Inferred from electronic annotation. Source: InterPro
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	NAD+ ADP-ribosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5QNZ9-1 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: DCA1DD4C001EA22F	FASTA	1,724	192,595
	10 20 30 40 50 60 MVMGIFANCI FCLKVKYLPQ QQKKKLQTDI KENGGKFSFS LNPQCTHIIL DNADVLSQYQ 70 80 90 100 110 120 LNSIQKNHVH IANPDFIWKS IREKRLLDVK NYDPYKPLDI TPPPDQKASS SEVKTEGLCP 130 140 150 160 170 180 DSATEEEDTV ELTEFGMQNV EIPHLPQDFE VAKYNTLEKV GMEGGQEAVV VELQCSRDSR 190 200 210 220 230 240 DCPFLISSHF LLDDGMETRR QFAIKKTSED ASEYFENYIE ELKKQGFLLR EHFTPEATQL 250 260 270 280 290 300 ASEQLQALLL EEVMNSSTLS QEVSDLVEMI WAEALGHLEH MLLKPVNRIS LNDVSKAEGI 310 320 330 340 350 360 LLLVKAALKN GETAEQLQKM MTEFYRLIPH KGTMPKEVNL GLLAKKADLC QLIRDMVNVC 370 380 390 400 410 420 ETNLSKPNPP SLAKYRALRC KIEHVEQNTE EFLRVRKEVL QNHHSKSPVD VLQIFRVGRV 430 440 450 460 470 480 NETTEFLSKL GNVRPLLHGS PVQNIVGILC RGLLLPKVVE DRGVQRTDVG NLGSGIYFSD 490 500 510 520 530 540 SLSTSIKYSH PGETDGTRLL LICDVALGKC MDLHEKDFSL TEAPPGYDSV HGVSQTASVT 550 560 570 580 590 600 TDFEDDEFVV YKTNQVKMKY IIKFSMPGDQ IKDFHPSDHT ELEEYRPEFS NFSKVEDYQL 610 620 630 640 650 660 PDAKTSSSTK AGLQDASGNL VPLEDVHIKG RIIDTVAQVI VFQTYTNKSH VPIEAKYIFP 670 680 690 700 710 720 LDDKAAVCGF EAFINGKHIV GEIKEKEEAQ QEYLEAVTQG HGAYLMSQDA PDVFTVSVGN 730 740 750 760 770 780 LPPKAKVLIK ITYITELSIL GTVGVFFMPA TVAPWQQDKA LNENLQDTVE KICIKEIGTK 790 800 810 820 830 840 QSFSLTMSIE MPYVIEFIFS DTHELKQKRT DCKAVISTME GSSLDSSGFS LHIGLSAAYL 850 860 870 880 890 900 PRMWVEKHPE KESEACMLVF QPDLDVDLPD LASESEVIIC LDCSSSMEGV TFLQAKQIAL 910 920 930 940 950 960 HALSLVGEKQ KVNIIQFGTG YKELFSYPKH ITSNTMAAEF IMSATPTMGN TDFWKTLRYL 970 980 990 1000 1010 1020 SLLYPARGSR NILLVSDGHL QDESLTLQLV KRSRPHTRLF ACGIGSTANR HVLRILSQCG 1030 1040 1050 1060 1070 1080 AGVFEYFNAK SKHSWRKQIE DQMTRLCSPS CHSVSVKWQQ LNPDVPEALQ APAQVPSLFL 1090 1100 1110 1120 1130 1140 NDRLLVYGFI PHCTQATLCA LIQEKEFRTM VSTTELQKTT GTMIHKLAAR ALIRDYEDGI 1150 1160 1170 1180 1190 1200 LHENETSHEM KKQTLKSLII KLSKENSLIT QFTSFVAVEK RDENESPFPD IPKVSELIAK 1210 1220 1230 1240 1250 1260 EDVDFLPYMS WQGEPQEAVR NQSLLASSEW PELRLSKRKH RKIPFSKRKM ELSQPEVSED 1270 1280 1290 1300 1310 1320 FEEDGLGVLP AFTSNLERGG VEKLLDLSWT ESCKPTATEP LFKKVSPWET STSSFFPILA 1330 1340 1350 1360 1370 1380 PAVGSYLPPT ARAHSPASLS FASYRQVASF GSAAPPRQFD ASQFSQGPVP GTCADWIPQS 1390 1400 1410 1420 1430 1440 ASCPTGPPQN PPSSPYCGIV FSGSSLSSAQ SAPLQHPGGF TTRPSAGTFP ELDSPQLHFS 1450 1460 1470 1480 1490 1500 LPTDPDPIRG FGSYHPSASS PFHFQPSAAS LTANLRLPMA SALPEALCSQ SRTTPVDLCL 1510 1520 1530 1540 1550 1560 LEESVGSLEG SRCPVFAFQS SDTESDELSE VLQDSCFLQI KCDTKDDSIL CFLEVKEEDE 1570 1580 1590 1600 1610 1620 IVCIQHWQDA VPWTELLSLQ TEDGFWKLTP ELGLILNLNT NGLHSFLKQK GIQSLGVKGR 1630 1640 1650 1660 1670 1680 ECLLDLIATM LVLQFIRTRL EKEGIVFKSL MKMDDASISR NIPWAFEAIK QASEWVRRTE 1690 1700 1710 1720 GQYPSICPRL ELGNDWDSAT KQLLGLQPIS TVSPLHRVLH YSQG

References

[1]	Tromans A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL359763 Genomic DNA. Translation: CAI12394.1.
IPI	IPI00296909.
RefSeq	NP_006428.2.
UniGene	Hs.591227
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q5QNZ9.
Genome annotation databases
Ensembl	ENSG00000102699. Homo sapiens. [Contig view]
GeneID	143.
KEGG	hsa:143.
Organism-specific databases
HGNC	HGNC:271. PARP4.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q5QNZ9.
OMA	Q5QNZ9. NQVKMKY.
Gene expression databases
ArrayExpress	Q5QNZ9.
Bgee	Q5QNZ9.
Family and domain databases
InterPro	IPR001357. BRCT. IPR012317. PARP_catalytic. IPR004102. PARP_reg. IPR013694. VIT. IPR006587. VIT_met. IPR002035. VWF_A. [Graphical view]
Gene3D	G3DSA:1.20.142.10. PARP_reg. 1 hit.
Pfam	PF00533. BRCT. 1 hit. PF00644. PARP. 1 hit. PF08487. VIT. 1 hit. PF00092. VWA. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 1 hit. SM00609. VIT. 1 hit. SM00327. VWA. 1 hit. [Graphical view]
PROSITE	PS50172. BRCT. 1 hit. PS51060. PARP_ALPHA_HD. 1 hit. PS51059. PARP_CATALYTIC. 1 hit. PS50234. VWFA. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	569.

Entry information

Entry name

Q5QNZ9_HUMAN

Accession

Primary (citable) accession number: Q5QNZ9

Entry history

Integrated into UniProtKB/TrEMBL:	January 4, 2005
Last sequence update:	January 4, 2005
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)