Q5QNA6 (SCRL2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
SCAR-like protein 2

Gene names

Ordered Locus Names:	Os01g0208600, LOC_Os01g11040
ORF Names:	OSJNBa0016I09.25

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	1334 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex By similarity.
Subcellular location	Cytoplasm › cytoskeleton By similarity.
Sequence similarities	Belongs to the SCAR/WAVE family. Contains 1 WH2 domain.

Ontologies

Keywords
Cellular component	Cytoplasm Cytoskeleton
Ligand	Actin-binding
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW cytoskeleton Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	actin binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1334	1334	SCAR-like protein 2		PRO_0000189010
Regions
	Domain	1271 – 1289	19	WH2
	Compositional bias	13 – 43	31	Gly-rich
	Compositional bias	1128 – 1149	22	Pro-rich
Experimental info
	Sequence conflict	32	1	G → R in AK120865. Ref.2
	Sequence conflict	38	1	A → V in AK120865. Ref.2
	Sequence conflict	209	1	K → E in AK120865. Ref.2
	Sequence conflict	598	1	P → S in AK120865. Ref.2
	Sequence conflict	768	1	Y → C in AK067713. Ref.2
	Sequence conflict	870	1	S → T in AK067713. Ref.2
	Sequence conflict	915	1	Q → K in AK067713. Ref.2
	Sequence conflict	1315	1	A → V in AK104676. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q5QNA6 [UniParc]. Last modified January 4, 2005. Version 1. Checksum: B53B20DD81750E6F	FASTA	1,334	144,358
	10 20 30 40 50 60 MPLVRFEVRN EVGLGDPDLY GGGGGGGGGG GGGGVGAAAK KGGEAEPKAL LEGVAVAGLV 70 80 90 100 110 120 GILRQLGDLA EFAADVFHDL HEQVITTSAR GRKVLTRVQN IEAALPSLEK AVKNQKSHIH 130 140 150 160 170 180 FTYVPGSDWH AQLKDEQNHL LSSDLPRFMM DSYEECRDPP RLYLLDKFDN AGAGACSRRH 190 200 210 220 230 240 SDPSYFKKAW DMMRADKTGN FQREKKSQKI KRKGSRLREP YHGQTTPRQR NGELQRALTA 250 260 270 280 290 300 VQLTSRHFAT PSTDGRSLSE NRSTSDVRSN PDNISRSSSF SSKARLSFTE QVLDTKPTVV 310 320 330 340 350 360 PHENGHDKLS NNNLHKLSNT PLHTRLNGTS ADDLGDDLKQ SSLLDDMTAR SPSVKWDEKA 370 380 390 400 410 420 EITMSTTSVY CDDVVMDKAE HVQSKCISPE QQEIDHREME TLEQQEALHQ KAKQLLVSSG 430 440 450 460 470 480 LNHHDEVPSE TDNYVDALNT LESETETEPE LQTKSRVKPV PSLNVDVPQV ELIDNIVTES 490 500 510 520 530 540 PDSSVAEFPD AYQNSSMPPA PESAADFPSL SSADAPDISE PVLSGYTANP HPEVSAIATN 550 560 570 580 590 600 TPVSNTEDAP GPLEISESAS RAYIITLPNQ SLPDSKEIPD SKAEDAPIDS PEKLEPGPSS 610 620 630 640 650 660 YTPTIPIKES SIVSQNTNAE NVSGDCSEGT ACAISYSQHI ISDKPTNEVS ATNSSPDDTS 670 680 690 700 710 720 SDEDTVESGG IVEVSNSQPM PLNDSLENGC ATQGLPANAP TNSTGVSSVK LWTNAGLFGL 730 740 750 760 770 780 EPSKPPVFGA HDGPKEDTTP GHTQPQLCHS TGCPEVHFSK PTESAQVYVP NGNSPITSSF 790 800 810 820 830 840 VGKLVGICPG STSHSSETNQ STVRTPDTVI GQTEGSTGCS TSFEHSDHKN IIGKQTSISE 850 860 870 880 890 900 LLESEDSAEN GAEMFSKTDM TGRNNMNQVS ASSFSSIAQR FLANTLQRRT PKYTDLPMSS 910 920 930 940 950 960 VIVNTDANGT DESTQISSLA PNETTFEASQ FEKKTENDTN GLPKSSLFSS SHYSEKSSPP 970 980 990 1000 1010 1020 LEYMKISFHP MSAFEMSKLD LDFSDENLHE NADDMMLPTF QLLPGSSVPQ LGSGSESEDD 1030 1040 1050 1060 1070 1080 TFGRSYSYSS YDDLSPRLYS NSELWDQEDA NGLEDHDMHN NPNQIGSFGA PISSFVEFEQ 1090 1100 1110 1120 1130 1140 MDLSGAKSTV SLTDLGDDNG LGTLDSHPAG ELPNFDTLMA HQNEAFIPHN PVSLSPDEGQ 1150 1160 1170 1180 1190 1200 LPPPPPLPPM QWRTMRQVAS VEEGRGSAAK EDMLESTSDL PPVHTPVQEE HLLPIAPPDQ 1210 1220 1230 1240 1250 1260 QNLLPIAPPD QQGHAKENDR KVDGVKEISN PLDIEIRASL LQQIRDKSGQ QKLNGHEKSK 1270 1280 1290 1300 1310 1320 AVGNDTKNLD EREELLQQIR SKTFNLRRTN ASKTNTSSPT TANSSVVAIL EKANAIRQAV 1330 ASDEGGDDDS WSDI

References

[1]

"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

[2]

"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003052 Genomic DNA. Translation: BAD73100.1. AK067713 mRNA. No translation available. AK104676 mRNA. No translation available. AK120865 mRNA. No translation available.
RefSeq	NP_001172227.1. NM_001185298.1.
UniGene	Os.28458.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q5QNA6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os01g11040.1; LOC_Os01g11040.1; LOC_Os01g11040.
GeneID	9268854.
KEGG	osa:9268854.
Organism-specific databases
Gramene	Q5QNA6.
Phylogenomic databases
OMA	MKISFHP.
Family and domain databases
InterPro	IPR003124. WH2_actin-bd. [Graphical view]
PROSITE	PS51082. WH2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SCRL2_ORYSJ

Accession

Primary (citable) accession number: Q5QNA6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 6, 2005
Last sequence update:	January 4, 2005
Last modified:	September 21, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program