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Protein

DNA cross-link repair 1A protein

Gene

DCLRE1A

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be required for DNA interstrand cross-link repair.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Enzyme and pathway databases

ReactomeiR-GGA-353248. DNA damage recognition in global genomic repair.
R-GGA-353303. Nucleotide Excision Repair.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA cross-link repair 1A protein
Alternative name(s):
SNM1 homolog A
Short name:
chSNM1A
Gene namesi
Name:DCLRE1A
Synonyms:SNM1A
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 972972DNA cross-link repair 1A proteinPRO_0000209118Add
BLAST

Proteomic databases

PaxDbiQ5QJC4.

Interactioni

Subunit structurei

Binds PIAS1.

Protein-protein interaction databases

STRINGi9031.ENSGALP00000032457.

Structurei

3D structure databases

ProteinModelPortaliQ5QJC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1361. Eukaryota.
COG1236. LUCA.
HOGENOMiHOG000168450.
HOVERGENiHBG081418.
InParanoidiQ5QJC4.
KOiK15340.
PhylomeDBiQ5QJC4.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR011084. DRMBL.
IPR001279. Metallo-B-lactamas.
[Graphical view]
PfamiPF07522. DRMBL. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5QJC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEDVLLEED IWEYKSIRKR KPQSNPDSTS VSMQTVTKGK CRPKRKGSGN
60 70 80 90 100
RKKSVEKNST PQKSEQRLRP SEDLDPCKDD SSVYAQESVS SLTEQGSPST
110 120 130 140 150
RPVCDGYCPS CQMPFSLLVV QTPRWHVAEC LDTPGSVEKE CPDGLLCTST
160 170 180 190 200
IPSHYKRYSH FLLAASRAGE YLVNSTANTV ERKMTCSTAA KSSCFPSPVE
210 220 230 240 250
DSQAEKPSKN LKNVPNNECT SKIKDSEQRK SLNITSESTS SFADVQKPQQ
260 270 280 290 300
VFQLTQTTDN SCKFEFYDFT SSQESVSEDL CSQKDTSQPS LLQSKADFSD
310 320 330 340 350
WEISYSPLST CEESEGEAEE EKEVKTSQNK LLKVQNFEGP ESNTEVFKFK
360 370 380 390 400
KQHCEEINTS SCLYHSEKSA SQSHVDSKCS NSPCVDNQQE MLSAESSFPL
410 420 430 440 450
NCNQEFQQPG LLSPAINTGN KESQDKGACV LDSVYSCLTR TQSLLLTEGG
460 470 480 490 500
RSPLSQKNKV LRAPSVVLTN TDKMTADATE KGTCQESLQP AVKKEENLDS
510 520 530 540 550
TGVCFPSPIS KTVSSHSLAS MNAKSSPAKE LKQMDIGVFF GLKPKVKEES
560 570 580 590 600
KGEACLSEGK QIPSSVAPSG KRPRQQKRKA EGSVEDLEAV EESSNKDGGD
610 620 630 640 650
ANVTSGGQRK WRKRFRESST TDEGARKKQC PFYKKIPGTG FTVDAFQYGE
660 670 680 690 700
IEGCTAYFLT HFHSDHYCGL TKNFVFPLYC NKITGNLVKS KLRVKEQYIN
710 720 730 740 750
VLPMDTECIV NGIKVLLLDA NHCPGATMIL FYLPSGTAIL HTGDFRADPS
760 770 780 790 800
MERYPALIGQ KIHTLYLDTT YCSPEYTFPS QQEVIQFAVN TAFEMVTLNP
810 820 830 840 850
RTLVVCGTYS IGKEKVFLAI AEVLGSKASM SRDKYKTLQC LESAAVNSLI
860 870 880 890 900
TMNWDGTLLH ILPMMQINFK GLQDHLNKFS ENFDQVLAFK PTGWTYSDSC
910 920 930 940 950
LSVMDIKPQT RGNITIYGIP YSEHSSYLEM KRFVQWLKPQ KIIPTVNVGD
960 970
WRARSLMEKH FRDWMIEGSG HK
Length:972
Mass (Da):108,328
Last modified:January 4, 2005 - v1
Checksum:iA87696D13B635514
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY376896 mRNA. Translation: AAR27404.1.
RefSeqiNP_001008683.1. NM_001008683.1.
UniGeneiGga.22844.

Genome annotation databases

GeneIDi423902.
KEGGigga:423902.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY376896 mRNA. Translation: AAR27404.1.
RefSeqiNP_001008683.1. NM_001008683.1.
UniGeneiGga.22844.

3D structure databases

ProteinModelPortaliQ5QJC4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000032457.

Proteomic databases

PaxDbiQ5QJC4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi423902.
KEGGigga:423902.

Organism-specific databases

CTDi9937.

Phylogenomic databases

eggNOGiKOG1361. Eukaryota.
COG1236. LUCA.
HOGENOMiHOG000168450.
HOVERGENiHBG081418.
InParanoidiQ5QJC4.
KOiK15340.
PhylomeDBiQ5QJC4.

Enzyme and pathway databases

ReactomeiR-GGA-353248. DNA damage recognition in global genomic repair.
R-GGA-353303. Nucleotide Excision Repair.

Miscellaneous databases

PROiQ5QJC4.

Family and domain databases

Gene3Di3.60.15.10. 1 hit.
InterProiIPR011084. DRMBL.
IPR001279. Metallo-B-lactamas.
[Graphical view]
PfamiPF07522. DRMBL. 1 hit.
[Graphical view]
SUPFAMiSSF56281. SSF56281. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH PIAS1.

Entry informationi

Entry nameiDCR1A_CHICK
AccessioniPrimary (citable) accession number: Q5QJC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: January 4, 2005
Last modified: July 6, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.