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Protein
Submitted name:

Retinoic acid receptor beta 5

Gene

RARB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 41Nuclear receptorPROSITE-ProRule annotationAdd BLAST41

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid receptor beta 5Imported
Submitted name:
Retinoic acid receptor beta variant 2Imported
Submitted name:
Retinoic acid receptor, beta, isoform CRA_bImported
Gene namesi
Name:RARBImported
Synonyms:NR1B2Imported
ORF Names:hCG_26863Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000077092.18.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34226.

PTM / Processingi

Proteomic databases

MaxQBiQ5QHG3.

Expressioni

Gene expression databases

BgeeiENSG00000077092.

Structurei

3D structure databases

SMRiQ5QHG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 41Nuclear receptorInterPro annotationAdd BLAST41

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOGENOMiHOG000010312.
HOVERGENiHBG005606.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR003078. Retinoic_acid_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01292. RETNOICACIDR.
PR00398. STRDHORMONER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5QHG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYTCHRDKN CVINKVTRNR CQYCRLQKCF EVGMSKESVR NDRNKKKKET
60 70 80 90 100
SKQECTESYE MTAELDDLTE KIRKAHQETF PSLCQLGKYT TNSSADHRVR
110 120 130 140 150
LDLGLWDKFS ELATKCIIKI VEFAKRLPGF TGLTIADQIT LLKAACLDIL
160 170 180 190 200
ILRICTRYTP EQDTMTFSDG LTLNRTQMHN AGFGPLTDLV FTFANQLLPL
210 220 230 240 250
EMDDTETGLL SAICLICGDR QDLEEPTKVD KLQEPLLEAL KIYIRKRRPS
260 270 280 290 300
KPHMFPKILM KITDLRSISA KGAERVITLK MEIPGSMPPL IQEMLENSEG
310 320 330
HEPLTPSSSG NTAEHSPSIS PSSVENSGVS QSPLVQ
Length:336
Mass (Da):37,932
Last modified:May 10, 2005 - v1
Checksum:iD248E5CAB87DA44E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY501390 mRNA. Translation: AAS85757.1.
HQ692863 mRNA. Translation: ADZ17374.1.
CH471055 Genomic DNA. Translation: EAW64355.1.
RefSeqiNP_001277146.1. NM_001290217.1.
NP_001277205.1. NM_001290276.1.
NP_057236.1. NM_016152.3.
UniGeneiHs.543218.
Hs.581530.
Hs.654490.
Hs.733004.

Genome annotation databases

GeneIDi5915.
UCSCiuc003cdi.3. human.

Similar proteinsi

Entry informationi

Entry nameiQ5QHG3_HUMAN
AccessioniPrimary (citable) accession number: Q5QHG3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 22, 2017
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.