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Protein
Submitted name:

Retinoic acid receptor beta 5

Gene

RARB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1 – 41Nuclear receptorPROSITE-ProRule annotationAdd BLAST41

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Retinoic acid receptor beta 5Imported
Submitted name:
Retinoic acid receptor beta variant 2Imported
Submitted name:
Retinoic acid receptor, beta, isoform CRA_bImported
Gene namesi
Name:RARBImported
Synonyms:NR1B2Imported
ORF Names:hCG_26863Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000077092.18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34226

Expressioni

Gene expression databases

BgeeiENSG00000077092

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 41Nuclear receptorInterPro annotationAdd BLAST41

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili58 – 78Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
HOGENOMiHOG000010312
HOVERGENiHBG005606

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR003078 Retinoic_acid_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01292 RETNOICACIDR
PR00398 STRDHORMONER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5QHG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIYTCHRDKN CVINKVTRNR CQYCRLQKCF EVGMSKESVR NDRNKKKKET
60 70 80 90 100
SKQECTESYE MTAELDDLTE KIRKAHQETF PSLCQLGKYT TNSSADHRVR
110 120 130 140 150
LDLGLWDKFS ELATKCIIKI VEFAKRLPGF TGLTIADQIT LLKAACLDIL
160 170 180 190 200
ILRICTRYTP EQDTMTFSDG LTLNRTQMHN AGFGPLTDLV FTFANQLLPL
210 220 230 240 250
EMDDTETGLL SAICLICGDR QDLEEPTKVD KLQEPLLEAL KIYIRKRRPS
260 270 280 290 300
KPHMFPKILM KITDLRSISA KGAERVITLK MEIPGSMPPL IQEMLENSEG
310 320 330
HEPLTPSSSG NTAEHSPSIS PSSVENSGVS QSPLVQ
Length:336
Mass (Da):37,932
Last modified:May 10, 2005 - v1
Checksum:iD248E5CAB87DA44E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY501390 mRNA Translation: AAS85757.1
HQ692863 mRNA Translation: ADZ17374.1
CH471055 Genomic DNA Translation: EAW64355.1
RefSeqiNP_001277146.1, NM_001290217.1
NP_001277205.1, NM_001290276.1
NP_057236.1, NM_016152.3
UniGeneiHs.543218
Hs.581530
Hs.654490
Hs.733004

Genome annotation databases

GeneIDi5915
UCSCiuc003cdi.3 human

Similar proteinsi

Entry informationi

Entry nameiQ5QHG3_HUMAN
AccessioniPrimary (citable) accession number: Q5QHG3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: March 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health