Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5QD04

- TAAR9_MOUSE

UniProt

Q5QD04 - TAAR9_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Trace amine-associated receptor 9

Gene

Taar9

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Orphan olfactory receptor specific for trace amines.By similarity

GO - Molecular functioni

  1. trace-amine receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Trace amine-associated receptor 9
Short name:
TaR-9
Short name:
Trace amine receptor 9
Short name:
mTaar9
Gene namesi
Name:Taar9
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 10

Organism-specific databases

MGIiMGI:3527454. Taar9.

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Mice lacking Taar2, Taar3, Taar4, Taar5, Taar6, Taar7a, Taar7b, Taar7d, Taar7e, Taar7f, Taar8a, Taar8b, Taar8c and Taar9 show no visible phenotype or behavioral deficits. They however show an absence of aversion to low concentrations of amines such as 2-phenylethylamine, isopentylamine, N-methylpiperidine and cadaverine.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Trace amine-associated receptor 9PRO_0000070182Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi19 – 191N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi105 ↔ 190PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiQ5QD04.

Expressioni

Tissue specificityi

Specifically expressed in neurons of the olfactory epithelium.1 Publication

Gene expression databases

CleanExiMM_TAAR9.
GenevestigatoriQ5QD04.

Structurei

3D structure databases

ProteinModelPortaliQ5QD04.
SMRiQ5QD04. Positions 38-323.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3333ExtracellularSequence AnalysisAdd
BLAST
Topological domaini55 – 6814CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini90 – 10718ExtracellularSequence AnalysisAdd
BLAST
Topological domaini129 – 14719CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini169 – 19729ExtracellularSequence AnalysisAdd
BLAST
Topological domaini219 – 25941CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini281 – 29414ExtracellularSequence AnalysisAdd
BLAST
Topological domaini316 – 34833CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei34 – 5421Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei69 – 8921Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei108 – 12821Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei148 – 16821Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei198 – 21821Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei260 – 28021Helical; Name=6Sequence AnalysisAdd
BLAST
Transmembranei295 – 31521Helical; Name=7Sequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG262944.
GeneTreeiENSGT00760000118774.
HOGENOMiHOG000239243.
HOVERGENiHBG106962.
InParanoidiQ5QD04.
KOiK05051.
OMAiCIALSWF.
OrthoDBiEOG7966GS.
PhylomeDBiQ5QD04.
TreeFamiTF343107.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR009132. TAAR_fam.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01830. TRACEAMINER.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5QD04-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSDFSPEPP MELCYENVNG SCIKSSYAPW PRAILYGVLG LGALLAVFGN
60 70 80 90 100
LLVIIAILHF KQLHTPTNFL VASLACADFL VGVTVMPFST VRSVESCWYF
110 120 130 140 150
GESYCKFHTC FDTSFCFASL FHLCCISIDR YIAVTDPLTY PTKFTVSVSG
160 170 180 190 200
LCIALSWFFS VTYSFSIFYT GANEEGIEEL VVALTCVGGC QAPLNQNWVL
210 220 230 240 250
LCFLLFFLPT VVMVFLYGRI FLVAKYQARK IEGTANQAQA SSESYKERVA
260 270 280 290 300
KRERKAAKTL GIAMAAFLVS WLPYIIDAVI DAYMNFITPA YVYEILVWCV
310 320 330 340
YYNSAMNPLI YAFFYPWFRK AIKLIVSGKV FRADSSTTNL FSEEAGAG
Length:348
Mass (Da):38,901
Last modified:January 4, 2005 - v1
Checksum:i0164AAF9C5474BA8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY702340 Genomic DNA. Translation: AAV70149.1.
BC139084 mRNA. Translation: AAI39085.1.
BC139085 mRNA. Translation: AAI39086.1.
CCDSiCCDS23748.1.
RefSeqiNP_001010831.1. NM_001010831.1.
UniGeneiMm.300923.

Genome annotation databases

EnsembliENSMUST00000041180; ENSMUSP00000043552; ENSMUSG00000037424.
GeneIDi503558.
KEGGimmu:503558.
UCSCiuc007eqr.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY702340 Genomic DNA. Translation: AAV70149.1 .
BC139084 mRNA. Translation: AAI39085.1 .
BC139085 mRNA. Translation: AAI39086.1 .
CCDSi CCDS23748.1.
RefSeqi NP_001010831.1. NM_001010831.1.
UniGenei Mm.300923.

3D structure databases

ProteinModelPortali Q5QD04.
SMRi Q5QD04. Positions 38-323.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Proteomic databases

PRIDEi Q5QD04.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000041180 ; ENSMUSP00000043552 ; ENSMUSG00000037424 .
GeneIDi 503558.
KEGGi mmu:503558.
UCSCi uc007eqr.1. mouse.

Organism-specific databases

CTDi 134860.
MGIi MGI:3527454. Taar9.

Phylogenomic databases

eggNOGi NOG262944.
GeneTreei ENSGT00760000118774.
HOGENOMi HOG000239243.
HOVERGENi HBG106962.
InParanoidi Q5QD04.
KOi K05051.
OMAi CIALSWF.
OrthoDBi EOG7966GS.
PhylomeDBi Q5QD04.
TreeFami TF343107.

Miscellaneous databases

NextBioi 411844.
PROi Q5QD04.
SOURCEi Search...

Gene expression databases

CleanExi MM_TAAR9.
Genevestigatori Q5QD04.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR009132. TAAR_fam.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR01830. TRACEAMINER.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors."
    Lindemann L., Ebeling M., Kratochwil N.A., Bunzow J.R., Grandy D.K., Hoener M.C.
    Genomics 85:372-385(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: C57BL/6.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. "A second class of chemosensory receptors in the olfactory epithelium."
    Liberles S.D., Buck L.B.
    Nature 442:645-650(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.
  4. "Non-redundant coding of aversive odours in the main olfactory pathway."
    Dewan A., Pacifico R., Zhan R., Rinberg D., Bozza T.
    Nature 497:486-489(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: DISRUPTION PHENOTYPE.

Entry informationi

Entry nameiTAAR9_MOUSE
AccessioniPrimary (citable) accession number: Q5QD04
Secondary accession number(s): B2RT07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: January 4, 2005
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3