RAR-like GTPase variant - Homo sapiens (Human)

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Unreviewed, UniProtKB/TrEMBL Q5PXE8 (Q5PXE8_HUMAN)

Last modified November 25, 2008. Version 35. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
RAR-like GTPase variant EMBL AAV83924.1

Gene names

Name:

RAB40C EMBL AAV83924.1

Organism

Homo sapiens (Human) EMBL AAV83924.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Pathway

Protein modification; protein ubiquitination. Spearmint SPM001496

Sequence similarities

Belongs to the small GTPase superfamily. Rab family. RuleBase RU003315V0

Contains 1 SOCS box domain. Spearmint SPM001496

Ontologies

Keywords
Biological process	Ubl conjugation pathway Spearmint SPM001496
Ligand	GTP-binding RuleBase RU003312V0 Spearmint SPM003579 Nucleotide-binding
PTM	Lipoprotein RuleBase RU003611V0
Gene Ontology (GO)
Uncategorized	ubiquitin cycle Inferred from electronic annotation. Source: UniProtKB-KW
Biological process	protein transport Inferred from electronic annotation. Source: InterPro small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q5PXE8-1 [UniParc].

Last modified January 4, 2005. Version 1.
Checksum: 8D0754A7549180B7
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262

29,226

        10         20         30         40         50         60 
MGSQGSPVKS YDYLLKFLLV GDSDVGKGEI LESLQDGAAE SPYAYSNGID YKTTTILLDG 

        70         80         90        100        110        120 
RRVKLELWDT SGQGRFCTIF RSYSRGAQGI LLVYDITNRW SFDGIDRWIK EIDERQVPTE 

       130        140        150        160        170        180 
QARAYAEKNC MTFFEVSPLC NFNVIESFTE LSRIVLMRHG MEKIWRPNRV FSLQDLCCRA 

       190        200        210        220        230        240 
IVSCTPVHLI DKLPLPVTIK SHLKSFSMAN GMNAVMMHGR SYSLASGAGG GGSKGNSLKR 

       250        260 
SKSIRPPQSP PQNCSRSNCK IS

References

[1]	"Sequencing of E. coli expression clones for human proteins." Sievert V., Buessow K. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL AAV83924.1.

Cross-references

Sequence databases
	AY823398 mRNA. Translation: AAV83924.1.
UniGene	Hs.459630
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000197562. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:18285. RAB40C.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q5PXE8.
Family and domain databases
InterPro	IPR003579. GTPase_Rab. IPR013753. Ras. IPR001806. Ras_GTPase. IPR005225. Small_GTP_bd. IPR001496. SOCS_C. [Graphical view]
Pfam	PF00071. Ras. 1 hit. PF07525. SOCS_box. 1 hit. [Graphical view]
PRINTS	PR00449. RASTRNSFRMNG.
SMART	SM00175. RAB. 1 hit. SM00253. SOCS. 1 hit. [Graphical view]
TIGRFAMs	TIGR00231. small_GTP. 1 hit.
PROSITE	PS50225. SOCS. 1 hit. [Graphical view]

Entry information

Entry name

Q5PXE8_HUMAN

Accession

Primary (citable) accession number: Q5PXE8

Entry history

Integrated into UniProtKB/TrEMBL:	January 4, 2005
Last sequence update:	January 4, 2005
Last modified:	November 25, 2008
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information