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Protein

Beta-lactamase

Gene

blaSHV-1

Organism
Klebsiella pneumoniae
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotation
Biological processAntibiotic resistanceUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseUniRule annotationSAAS annotation (EC:3.5.2.6UniRule annotationSAAS annotation)
Gene namesi
Name:blaSHV-1Imported
Synonyms:blaCTX-MImported, blaSHVImported, blaSHV-11Imported, blaSHV1Imported, SHVImported, SHV-1Imported, shv-1Imported, SHV-1b-aImported
ORF Names:C2U50_04500Imported, CKJ89_14325Imported, CPT10_12585Imported, CR230_21245Imported
Encoded oniPlasmid pKP308Imported
Plasmid unnamedImported
OrganismiKlebsiella pneumoniaeImported
Taxonomic identifieri573 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000218952 Componenti: Unassembled WGS sequence
  • UP000236476 Componenti: Chromosome
  • UP000218464 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501430992022 – 286Beta-lactamaseSequence analysisAdd BLAST265

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108J4B Bacteria
COG2367 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR000871 Beta-lactam_class-A
IPR023650 Beta-lactam_class-A_AS
PRINTSiPR00118 BLACTAMASEA
SUPFAMiSSF56601 SSF56601, 1 hit
PROSITEiView protein in PROSITE
PS00146 BETA_LACTAMASE_A, 1 hit

Sequencei

Sequence statusi: Complete.

Q5PSW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYIRLCIIS LLATLPLAVH ASPQPLEQIK LSESQLSGRV GMIEMDLASG
60 70 80 90 100
RTLTAWRADE RFPMMSTFKV VLCGAVLARV DAGDEQLERK IHYRQQDLVD
110 120 130 140 150
YSPVSEKHLA DGMTVGELCA AAITMSDNSA ANLLLATVGG PAGLTAFLRQ
160 170 180 190 200
IGDNVTRLDR WETELNEALP GDARDTTTPA SMAATLRKLL TSQRLSARSQ
210 220 230 240 250
RQLLQWMVDD RVAGPLIRSV LPAGWFIADK TGAGERGARG IVALLGPNNK
260 270 280
AERIVVIYLR DTPASMAERN QQIAGIGAAL IEHWQR
Length:286
Mass (Da):31,224
Last modified:May 10, 2005 - v1
Checksum:iC78F42667E698E6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY826416 Genomic DNA Translation: AAV83794.1
DQ166781 Genomic DNA Translation: AAZ98826.1
DQ219474 Genomic DNA Translation: ABB01159.1
DQ355784 Genomic DNA Translation: ABC88472.1
DQ478720 Genomic DNA Translation: ABF29674.1
EF035564 Genomic DNA Translation: ABM89165.1
EF035565 Genomic DNA Translation: ABM89166.1
EF035566 Genomic DNA Translation: ABM89167.1
EF035567 Genomic DNA Translation: ABM89168.1
EU280315 Genomic DNA Translation: ABX76424.1
EU418908 Genomic DNA Translation: ACM04454.1
FJ685657 Genomic DNA Translation: ACO07069.1
FJ668799 Genomic DNA Translation: ACR66308.1
FJ668800 Genomic DNA Translation: ACR66309.1
FJ668804 Genomic DNA Translation: ACR66313.1
FJ668811 Genomic DNA Translation: ACR66320.1
FJ668813 Genomic DNA Translation: ACR66322.1
FJ668814 Genomic DNA Translation: ACR66323.1
FJ668818 Genomic DNA Translation: ACR66327.1
GQ380692 Genomic DNA Translation: ACU57153.1
GQ389701 Genomic DNA Translation: ACV32617.1
GQ407112 Genomic DNA Translation: ACV33199.1
GQ407113 Genomic DNA Translation: ACV33200.1
GQ407119 Genomic DNA Translation: ACV33206.1
GQ407121 Genomic DNA Translation: ACV33208.1
GQ407122 Genomic DNA Translation: ACV33209.1
GQ407123 Genomic DNA Translation: ACV33210.1
GQ407127 Genomic DNA Translation: ACV33214.1
GQ407128 Genomic DNA Translation: ACV33215.1
GQ407129 Genomic DNA Translation: ACV33216.1
GQ407131 Genomic DNA Translation: ACV33218.1
GQ407132 Genomic DNA Translation: ACV33219.1
GQ407133 Genomic DNA Translation: ACV33220.1
GQ407136 Genomic DNA Translation: ACV33223.1
GQ407137 Genomic DNA Translation: ACV33224.1
GQ407138 Genomic DNA Translation: ACV33225.1
GQ407140 Genomic DNA Translation: ACV33227.1
GQ407142 Genomic DNA Translation: ACV33229.1
GQ407144 Genomic DNA Translation: ACV33231.1
GQ407145 Genomic DNA Translation: ACV33232.1
GU083598 Genomic DNA Translation: ACY35991.1
GU083599 Genomic DNA Translation: ACY35992.1
GU064389 Genomic DNA Translation: ACY68236.1
HM751097 Genomic DNA Translation: ADR80603.1
HM751099 Genomic DNA Translation: ADR80605.1
HM751102 Genomic DNA Translation: ADR80608.1
JX268740 Genomic DNA Translation: AFN82169.1
KF585134 Genomic DNA Translation: AHB36952.1
CP024038 Genomic DNA Translation: ATO25096.1
CP026177 Genomic DNA Translation: AUV36037.1
NRQZ01000171 Genomic DNA Translation: PAW15597.1
NXFM01000009 Genomic DNA Translation: PCL81423.1
RefSeqiWP_001620095.1, NZ_PJQK01000015.1

Genome annotation databases

PATRICifig|573.1353.peg.2176

Similar proteinsi

Entry informationi

Entry nameiQ5PSW7_KLEPN
AccessioniPrimary (citable) accession number: Q5PSW7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 25, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported
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Main funding by: National Institutes of Health