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Q5PSW7 (Q5PSW7_KLEPN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

Beta-lactamase SHV-1 EMBL ABX76424.1

Beta-lactamase bla-SHV-1 EMBL ACV33215.1

Beta-lactamase blaSHV-1 EMBL ACU57153.1

Bla-SHV type 1 EMBL ABC88472.1

Broad-spectrum beta-lactamase SHV-1 EMBL AAV83794.1

Extended-spectrum beta-lactamase SHV-11 EMBL ABB01159.1

SHV type beta lactamase EMBL ABM89165.1

SHV type extended spectrum beta-lactamase EMBL AAZ98826.1

SHV-1 beta-lactamase EMBL ACM04454.1
Gene names
Name:blaSHV-1 EMBL AAV83794.1
Synonyms:blaCTX-M EMBL ACR66322.1, blaSHV EMBL ACR66308.1, blaSHV-11 EMBL ABB01159.1, blaSHV1 EMBL ACO07069.1, SHV EMBL ABM89167.1, SHV-1 EMBL ABM89165.1, shv-1 EMBL ABF29674.1, SHV-1b-a EMBL AAZ98826.1
Encoded onPlasmid pKP308 Ref.1 EMBL AAZ98826.1
Plasmid unnamed Ref.2 Ref.4 Ref.14 EMBL AAV83794.1
OrganismKlebsiella pneumoniae EMBL AAV83794.1
Taxonomic identifier573 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

A beta-lactam + H2O = a substituted beta-amino acid. SAAS SAAS012338

Ontologies

Keywords
   Biological processAntibiotic resistance SAAS SAAS012338
   Molecular functionHydrolase SAAS SAAS023650
   Technical termPlasmid EMBL AAV83794.1
Gene Ontology (GO)
   Biological_processbeta-lactam antibiotic catabolic process

Inferred from electronic annotation. Source: InterPro

response to antibiotic

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionbeta-lactamase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5PSW7 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: C78F42667E698E6C

FASTA28631,224
        10         20         30         40         50         60 
MRYIRLCIIS LLATLPLAVH ASPQPLEQIK LSESQLSGRV GMIEMDLASG RTLTAWRADE 

        70         80         90        100        110        120 
RFPMMSTFKV VLCGAVLARV DAGDEQLERK IHYRQQDLVD YSPVSEKHLA DGMTVGELCA 

       130        140        150        160        170        180 
AAITMSDNSA ANLLLATVGG PAGLTAFLRQ IGDNVTRLDR WETELNEALP GDARDTTTPA 

       190        200        210        220        230        240 
SMAATLRKLL TSQRLSARSQ RQLLQWMVDD RVAGPLIRSV LPAGWFIADK TGAGERGARG 

       250        260        270        280 
IVALLGPNNK AERIVVIYLR DTPASMAERN QQIAGIGAAL IEHWQR 

« Hide

References

[1]"A study on a novel SHV type extended spectrum beta-lactamase."
Li J., Cheng J., Li H., Wang Y.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: KPn308 EMBL AAZ98826.1.
[2]"Molecular epidemiology of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit."
Bagattini M., Crivaro V., Di Popolo A., Gentile F., Scarcella A., Triassi M., Villari P., Zarrilli R.
J. Antimicrob. Chemother. 57:979-982(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Kp 403 EMBL AAV83794.1.
[3]"Genetic Diversity of bla-SHV in Brazilian Klesiella pneumoniae isolates."
Nogueira M.C.L., Pacca C.C., Almeida M.T.G., Nogueira M.L.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]"Occurrence and molecular analysis of extended-spectrum and AmpC beta-lactamases in Enterobacteriaceae in China."
Zhu L.-X., Zhang Z.-W., Jiang D., Wang C., Du N., Zhang Q., Cheng J.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: TT-18 EMBL ABF29674.1.
[5]"SHV beta lactamase gene produced by Gram-negative bacteria isolated from AIIMS hospital, India."
Lal P., Kapil A., Das B.K.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Kp297 EMBL ABM89168.1, Kp311 EMBL ABM89165.1, Kp344 EMBL ABM89166.1 and Kp734 EMBL ABM89167.1.
[6]"Differential expression of bla(SHV) related to susceptibility to ampicillin in Klebsiella pneumoniae."
Fu Y., Zhang F., Zhang W., Chen X., Zhao Y., Ma J., Bao L., Song W., Ohsugi T., Urano T., Liu S.
Int. J. Antimicrob. Agents 29:344-347(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 753 EMBL ABB01159.1.
[7]"Detection of blaSHV in clinical strain Klebsiella pneumoniae."
Ben Achour N., Mercuri P., Chouchani C., Belhadj C., Ben Moussa M., Frere J.-M., Galleni M., Belhadj O.
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: ML3296 EMBL ABX76424.1.
[8]"Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool."
Zong Z., Partridge S.R., Thomas L., Iredell J.R.
Antimicrob. Agents Chemother. 52:4198-4202(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: JIE092 EMBL ACM04454.1.
[9]"Diversity of TEM-, SHV-, and CTX-M- Type beta-Lactamases Present in Clinical Isolates of Klebsiella pneumoniae from a Brazilian Hospital."
Tolentino F.M., Polotto M., Remeli G.A., Nogueira M.L., Nogueira M.C.L.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HB 100 EMBL ACV33232.1, HB 28 EMBL ACV33199.1, HB 29 EMBL ACV33200.1, HB 68 EMBL ACV33206.1, HB 71 EMBL ACV33208.1, HB 74 EMBL ACV33209.1, HB 76 EMBL ACV33210.1, HB 80 EMBL ACV33214.1, HB 81 EMBL ACV33215.1, HB 82 EMBL ACV33216.1, HB 84 EMBL ACV33218.1, HB 85 EMBL ACV33219.1, HB 86 EMBL ACV33220.1, HB 89 EMBL ACV33223.1, HB 90 EMBL ACV33224.1, HB 91 EMBL ACV33225.1, HB 94 EMBL ACV33227.1, HB 97 EMBL ACV33229.1 and HB 99 EMBL ACV33231.1.
[10]"Diversity of TEM-, SHV-, and CTX-M- type beta-lactamases present in clinical isolates of Klebsiella pneumoniae from a Brazilian hospital."
Tolentino F.M., Polotto M., Remeli G.A., Nogueira M.L., Nogueira M.C.L.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HB 2 EMBL ACU57153.1.
[11]"Diversity of TEM-, SHV-, CTX-M-Type Beta-Lactamases Present in Clinical Isolates of Klebsiella pneumoniae from a Brazilian Hospital."
Tolentino F.M., Polotto M., Remeli G.A., Nogueira M.L., Nogueira M.C.L.
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HB 12 EMBL ACV32617.1.
[12]"Diversity of TEM-, SHV-, and CTX-M- type beta-lactamases present in clinical isolates of Klebsiella pneumoniae from a Brazilian hospital."
Tolentino F.M., Polotto M., Remeli G.A., Nogueira M.L., Nogueira M.C.L.
Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HB 65 EMBL ACY68236.1.
[13]"Diversity of TEM-, SHV-, and CTX-M-type beta-lactamases present in clinical isolates of Klebsiella pneumoniae from a Brazilian hospital."
Tolentino F.M., Polotto M., Remeli G.A., Nogueira M.L., Nogueira M.C.L.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: HB 43 EMBL ACY35991.1 and HB 48 EMBL ACY35992.1.
[14]"Integrated detection of extended-spectrum-beta-lactam resistance by DNA microarray-based genotyping of TEM, SHV, and CTX-M genes."
Leinberger D.M., Grimm V., Rubtsova M., Weile J., Schroppel K., Wichelhaus T.A., Knabbe C., Schmid R.D., Bachmann T.T.
J. Clin. Microbiol. 48:460-471(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 10 EMBL ACR66309.1, 16 EMBL ACR66313.1, 35 EMBL ACR66320.1, 37 EMBL ACR66322.1, 42 EMBL ACR66323.1, 62 EMBL ACR66327.1 and 7 EMBL ACR66308.1.
[15]"Prevalence of the bla (SHV) gene in Klebsiella pneumoniae isolates obtained from hospital and community infections and from the microbiota of healthy individuals in Recife, Brazil."
Veras D.L., Alves L.C., Brayner F.A., Guedes D.R., Maciel M.A., Rocha C.R., de Souza Lopes A.C.
Curr. Microbiol. 62:1610-1616(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: K13R EMBL ADR80605.1, K16R EMBL ADR80608.1 and K3CM EMBL ADR80603.1.
[16]"Phenotypic and genotypic characterization of ?-lactam resistance in Klebsiella pneumoniae isolated from swine."
Zou L.K., Wang H.N., Zeng B., Zhang A.Y., Li J.N., Li X.T., Tian G.B., Wei K., Zhou Y.S., Xu C.W., Yang Z.R.
Vet. Microbiol. 149:139-146(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DY-x-X EMBL ACO07069.1.
[17]"Emergence of several beta-lactamases in Austria."
Barisic I., Mitteregger D., Goekler D., Hirschl A., Noehammer C., Wiesinger-Mayr H.
Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: AKH11/46 EMBL AFN82169.1.
[18]"Comparative genomics of an IncA/C multidrug resistance plasmid from Escherichia coli and Klebsiella species isolated from ICU patients."
Hazen T.H., Zhao L., Boutin M.A., Stancil A., Robinson G.L., Harris A.D., Rasko D.A., Johnson J.K.
Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 1830-2 EMBL AHB36952.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY826416 Genomic DNA. Translation: AAV83794.1.
DQ166781 Genomic DNA. Translation: AAZ98826.1.
DQ219474 Genomic DNA. Translation: ABB01159.1.
DQ355784 Genomic DNA. Translation: ABC88472.1.
DQ478720 Genomic DNA. Translation: ABF29674.1.
EF035564 Genomic DNA. Translation: ABM89165.1.
EF035565 Genomic DNA. Translation: ABM89166.1.
EF035566 Genomic DNA. Translation: ABM89167.1.
EF035567 Genomic DNA. Translation: ABM89168.1.
EU280315 Genomic DNA. Translation: ABX76424.1.
EU418908 Genomic DNA. Translation: ACM04454.1.
FJ685657 Genomic DNA. Translation: ACO07069.1.
FJ668799 Genomic DNA. Translation: ACR66308.1.
FJ668800 Genomic DNA. Translation: ACR66309.1.
FJ668804 Genomic DNA. Translation: ACR66313.1.
FJ668811 Genomic DNA. Translation: ACR66320.1.
FJ668813 Genomic DNA. Translation: ACR66322.1.
FJ668814 Genomic DNA. Translation: ACR66323.1.
FJ668818 Genomic DNA. Translation: ACR66327.1.
GQ380692 Genomic DNA. Translation: ACU57153.1.
GQ389701 Genomic DNA. Translation: ACV32617.1.
GQ407112 Genomic DNA. Translation: ACV33199.1.
GQ407113 Genomic DNA. Translation: ACV33200.1.
GQ407119 Genomic DNA. Translation: ACV33206.1.
GQ407121 Genomic DNA. Translation: ACV33208.1.
GQ407122 Genomic DNA. Translation: ACV33209.1.
GQ407123 Genomic DNA. Translation: ACV33210.1.
GQ407127 Genomic DNA. Translation: ACV33214.1.
GQ407128 Genomic DNA. Translation: ACV33215.1.
GQ407129 Genomic DNA. Translation: ACV33216.1.
GQ407131 Genomic DNA. Translation: ACV33218.1.
GQ407132 Genomic DNA. Translation: ACV33219.1.
GQ407133 Genomic DNA. Translation: ACV33220.1.
GQ407136 Genomic DNA. Translation: ACV33223.1.
GQ407137 Genomic DNA. Translation: ACV33224.1.
GQ407138 Genomic DNA. Translation: ACV33225.1.
GQ407140 Genomic DNA. Translation: ACV33227.1.
GQ407142 Genomic DNA. Translation: ACV33229.1.
GQ407144 Genomic DNA. Translation: ACV33231.1.
GQ407145 Genomic DNA. Translation: ACV33232.1.
GU083598 Genomic DNA. Translation: ACY35991.1.
GU083599 Genomic DNA. Translation: ACY35992.1.
GU064389 Genomic DNA. Translation: ACY68236.1.
HM751097 Genomic DNA. Translation: ADR80603.1.
HM751099 Genomic DNA. Translation: ADR80605.1.
HM751102 Genomic DNA. Translation: ADR80608.1.
JX268740 Genomic DNA. Translation: AFN82169.1.
KF585134 Genomic DNA. Translation: AHB36952.1.

3D structure databases

ProteinModelPortalQ5PSW7.
SMRQ5PSW7. Positions 22-286.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.710.10. 1 hit.
InterProIPR012338. Beta-lactam/transpept-like.
IPR000871. Beta-lactam_class-A/D.
IPR023650. Beta-lactam_class-A_AS.
[Graphical view]
PRINTSPR00118. BLACTAMASEA.
SUPFAMSSF56601. SSF56601. 1 hit.
PROSITEPS00146. BETA_LACTAMASE_A. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ5PSW7.

Entry information

Entry nameQ5PSW7_KLEPN
AccessionPrimary (citable) accession number: Q5PSW7
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 11, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)