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Q5PQZ2

- Q5PQZ2_DANRE

UniProt

Q5PQZ2 - Q5PQZ2_DANRE

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Protein
Submitted name: MAD homolog 1 (Drosophila)
Gene
smad1
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. BMP signaling pathway Source: UniProtKB
  2. embryonic pattern specification Source: UniProtKB
  3. transcription, DNA-templated Source: UniProtKB-KW
  4. transforming growth factor beta receptor signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
MAD homolog 1 (Drosophila)Imported
Submitted name:
Mothers against decapentaplegic homolog 1Imported
Gene namesi
Name:smad1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 1

Organism-specific databases

ZFINiZDB-GENE-991119-8. smad1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
  2. transcription factor complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotations

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00600000084186.
HOVERGENiHBG053353.
InParanoidiQ5PQZ2.
KOiK04676.
OrthoDBiEOG7W1540.

Family and domain databases

Gene3Di2.60.200.10. 1 hit.
3.90.520.10. 1 hit.
InterProiIPR013790. Dwarfin.
IPR003619. MAD_homology1_Dwarfin-type.
IPR013019. MAD_homology_MH1.
IPR017855. SMAD_dom-like.
IPR001132. SMAD_dom_Dwarfin-type.
IPR008984. SMAD_FHA_domain.
[Graphical view]
PANTHERiPTHR13703. PTHR13703. 1 hit.
PfamiPF03165. MH1. 1 hit.
PF03166. MH2. 1 hit.
[Graphical view]
SMARTiSM00523. DWA. 1 hit.
SM00524. DWB. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
SSF56366. SSF56366. 1 hit.
PROSITEiPS51075. MH1. 1 hit.
PS51076. MH2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5PQZ2-1 [UniParc]FASTAAdd to Basket

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MNVTSLFSFT SPAVKRLLGW KQGDEEEKWA EKAVDALVKK LKKKKGAMEE    50
LERALSCPGQ PSNCVTIPRS LDGRLQVSHR KGLPHVIYCR VWRWPDLQSH 100
HELKALECCE FPFGSKQKDV CINPYHYKRV DSPVLPPVLV PRNSEFNAKL 150
SMLPRFRNPL HQTEPPMPQN ATFPDSFPQQ PANALPFTPN SPTNSYPSSP 200
NSGTGSTATF PHSPSSSDPG SPFQMPETPP PAYMPPEEPM TQDCPQPMDT 250
NLLAPNLPLE ISNRTDVHPV AYQEPKHWCS IVYYELNNRV GEAFLASSTS 300
VLVDGFTDPS NNRNRFCLGL LSNVNRNSTI ENTRRHIGKG VHLYYVGGEV 350
YAECLSDSSI FVQSRNCNYH HGFHPTTVCK IPSRCSLKIF NNQEFAELLA 400
QSVNHGFEAV YELTKMCTIR MSFVKGWGAE YHRQDVTSTP CWIEIHLHGP 450
LQWLDKVLTQ MGSPHNPISS VS 472
Length:472
Mass (Da):53,067
Last modified:January 4, 2005 - v1
Checksum:i84E5360D1B611BC9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX276105 Genomic DNA. No translation available.
BC086962 mRNA. Translation: AAH86962.1.
RefSeqiXP_005160022.1. XM_005159965.1.
UniGeneiDr.76928.

Genome annotation databases

EnsembliENSDART00000033566; ENSDARP00000030150; ENSDARG00000027199.
GeneIDi30628.
KEGGidre:30628.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX276105 Genomic DNA. No translation available.
BC086962 mRNA. Translation: AAH86962.1 .
RefSeqi XP_005160022.1. XM_005159965.1.
UniGenei Dr.76928.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000033566 ; ENSDARP00000030150 ; ENSDARG00000027199 .
GeneIDi 30628.
KEGGi dre:30628.

Organism-specific databases

CTDi 4086.
ZFINi ZDB-GENE-991119-8. smad1.

Phylogenomic databases

GeneTreei ENSGT00600000084186.
HOVERGENi HBG053353.
InParanoidi Q5PQZ2.
KOi K04676.
OrthoDBi EOG7W1540.

Family and domain databases

Gene3Di 2.60.200.10. 1 hit.
3.90.520.10. 1 hit.
InterProi IPR013790. Dwarfin.
IPR003619. MAD_homology1_Dwarfin-type.
IPR013019. MAD_homology_MH1.
IPR017855. SMAD_dom-like.
IPR001132. SMAD_dom_Dwarfin-type.
IPR008984. SMAD_FHA_domain.
[Graphical view ]
PANTHERi PTHR13703. PTHR13703. 1 hit.
Pfami PF03165. MH1. 1 hit.
PF03166. MH2. 1 hit.
[Graphical view ]
SMARTi SM00523. DWA. 1 hit.
SM00524. DWB. 1 hit.
[Graphical view ]
SUPFAMi SSF49879. SSF49879. 1 hit.
SSF56366. SSF56366. 1 hit.
PROSITEi PS51075. MH1. 1 hit.
PS51076. MH2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: WholeImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  3. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiQ5PQZ2_DANRE
AccessioniPrimary (citable) accession number: Q5PQZ2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3
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