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Protein
Submitted name:

Guanylate binding protein 2

Gene

Gbp2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanylate binding protein 2Imported
Submitted name:
Guanylate nucleotide binding protein 2Imported
Submitted name:
Guanylate-binding protein 1Imported
Gene namesi
Name:Gbp2Imported
ORF Names:rCG_28968Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi621810. Gbp2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000031743.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 278GB1/RHD3-type GInterPro annotationAdd BLAST242

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili482 – 555Sequence analysisAdd BLAST74

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2037. Eukaryota.
ENOG410XR6Z. LUCA.
GeneTreeiENSGT00550000074475.
HOVERGENiHBG001979.
KOiK20897.
OMAiFINDETY.
OrthoDBiEOG091G03P3.

Family and domain databases

InterProiView protein in InterPro
IPR030386. G_GB1_RHD3_dom.
IPR003191. Guanylate-bd_C.
IPR015894. Guanylate-bd_N.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF02263. GBP. 1 hit.
PF02841. GBP_C. 1 hit.
SUPFAMiSSF48340. SSF48340. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS51715. G_GB1_RHD3. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5PQW8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMASEIHML QPMCLIENTE AHLVINQEAL RILSAINQPV VVVAIVGLYR
60 70 80 90 100
TGKSYLMNKL AGKRTGFSLG STVQSHTKGI WMWCVPHPKK AGQTLVLLDT
110 120 130 140 150
EGLEDVEKGD NQNDCWIFAL AVLLSSTFVY NSMGTINQQA MDQLHYVTEL
160 170 180 190 200
TDLIKSKSSP DQSGIDDSAN FVGFFPTFVW ALRDFSLELE VNGKLVTPDE
210 220 230 240 250
YLEHSLTLKK GADKKTKSFN EPRLCIRKFF PKRKCFIFDR PALRKQLCKL
260 270 280 290 300
ETLGEEELCS EFVEQVAEFT SYIFSYSAVK TLSGGIIVNG PRLKSLVQTY
310 320 330 340 350
VGAISSGSLP CMESAVLTLA QIENSAAVQK AITHYEEQMN QKIQMPTETL
360 370 380 390 400
QELLDLHRLI EREAIEIFLK NSFKDVDQKF QTELGNLLIS KRDAFIKKNS
410 420 430 440 450
DVSSAHCSDL IEDIFGPLEE EVKQGTFSKP GGYFLFLQMR QELEKKYNQA
460 470 480 490 500
PGKGLEAEAV LKKYFESKED IVETLLKTDQ SLTEAAKEIE VERIKAETAE
510 520 530 540 550
AANRELAEKQ EKFELMMQQK EESYQEHVRQ LTEKMKEEQK KLIEEQDNII
560 570 580 590
ALKLREQEKF LREGYENESK KLLREIENMK RRQSPGKCTI L
Length:591
Mass (Da):67,355
Last modified:January 4, 2005 - v1
Checksum:i3249C0EB57217176
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07013644 Genomic DNA. No translation available.
BC086991 mRNA. Translation: AAH86991.1.
CH473952 Genomic DNA. Translation: EDL82354.1.
RefSeqiNP_598308.1. NM_133624.2.
UniGeneiRn.25736.

Genome annotation databases

EnsembliENSRNOT00000068683; ENSRNOP00000061437; ENSRNOG00000031743.
GeneIDi171164.
KEGGirno:171164.

Similar proteinsi

Entry informationi

Entry nameiQ5PQW8_RAT
AccessioniPrimary (citable) accession number: Q5PQW8
Secondary accession number(s): D4A6I2
Entry historyiIntegrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: September 27, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported