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Protein

RNA-binding motif, single-stranded-interacting protein 1

Gene

Rbms1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA replication

Keywords - Ligandi

DNA-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding motif, single-stranded-interacting protein 1
Gene namesi
Name:Rbms1Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1307777. Rbms1.

Subcellular locationi

  • Nucleus By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 403403RNA-binding motif, single-stranded-interacting protein 1PRO_0000293625Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei208 – 2081PhosphothreonineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5PQP1.
PRIDEiQ5PQP1.

Expressioni

Gene expression databases

ExpressionAtlasiQ5PQP1. baseline and differential.
GenevisibleiQ5PQP1. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011682.

Structurei

3D structure databases

ProteinModelPortaliQ5PQP1.
SMRiQ5PQP1. Positions 62-224.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini62 – 13574RRM 1PROSITE-ProRule annotationAdd
BLAST
Domaini141 – 22686RRM 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 RRM (RNA recognition motif) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG4733. Eukaryota.
ENOG410XRB5. LUCA.
GeneTreeiENSGT00760000118913.
HOGENOMiHOG000008467.
HOVERGENiHBG053108.
InParanoidiQ5PQP1.
OMAiETRENKY.
OrthoDBiEOG71G9V3.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5PQP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKVWKQQMY PQYATYYYPQ YLQAKQSLVP AHPMAPPSPS TTSSNNNSSS
60 70 80 90 100
SSNSGWDQLS KTNLYIRGLP PNTTDQDLVK LCQPYGKIVS TKAILDKATN
110 120 130 140 150
KCKGYGFVDF DSPAAAQKAV SALKASGVQA QMAKQQEQDP TNLYISNLPL
160 170 180 190 200
SMDEQELENM LKPFGQVIST RVLRDSSGTS RGVGFARMES TEKCEAVIGH
210 220 230 240 250
FNGKFIKTPP GVSAPTEPLL CKFADGGQKK RQNPNKYIPN GRPWPREGEA
260 270 280 290 300
GMTLTYDPTT AALHNGFYPS PYSIATNRMI TQTSLTPYIA SPVSAYQVQS
310 320 330 340 350
PSWMQPQPYI LQHPGAVLTP SMEHTMSLQP ASMISPLAQQ MSHLSLGSTG
360 370 380 390 400
TYMPATSAMQ GAYLPQYTHM QTATVPVEEA SGQQQVTVET SNDHSPYTFP

PNK
Length:403
Mass (Da):44,068
Last modified:January 4, 2005 - v1
Checksum:i4DAE522D5B53545A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087094 mRNA. Translation: AAH87094.1.
RefSeqiNP_001012184.1. NM_001012184.1.
UniGeneiRn.98522.

Genome annotation databases

EnsembliENSRNOT00000011682; ENSRNOP00000011682; ENSRNOG00000008482.
GeneIDi362138.
KEGGirno:362138.
UCSCiRGD:1307777. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087094 mRNA. Translation: AAH87094.1.
RefSeqiNP_001012184.1. NM_001012184.1.
UniGeneiRn.98522.

3D structure databases

ProteinModelPortaliQ5PQP1.
SMRiQ5PQP1. Positions 62-224.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011682.

Proteomic databases

PaxDbiQ5PQP1.
PRIDEiQ5PQP1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000011682; ENSRNOP00000011682; ENSRNOG00000008482.
GeneIDi362138.
KEGGirno:362138.
UCSCiRGD:1307777. rat.

Organism-specific databases

CTDi5937.
RGDi1307777. Rbms1.

Phylogenomic databases

eggNOGiKOG4733. Eukaryota.
ENOG410XRB5. LUCA.
GeneTreeiENSGT00760000118913.
HOGENOMiHOG000008467.
HOVERGENiHBG053108.
InParanoidiQ5PQP1.
OMAiETRENKY.
OrthoDBiEOG71G9V3.

Miscellaneous databases

PROiQ5PQP1.

Gene expression databases

ExpressionAtlasiQ5PQP1. baseline and differential.
GenevisibleiQ5PQP1. RN.

Family and domain databases

Gene3Di3.30.70.330. 2 hits.
InterProiIPR002343. Hud_Sxl_RNA.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 2 hits.
[Graphical view]
PRINTSiPR00961. HUDSXLRNA.
SMARTiSM00360. RRM. 2 hits.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 2 hits.
PROSITEiPS50102. RRM. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: HeartImported.

Entry informationi

Entry nameiRBMS1_RAT
AccessioniPrimary (citable) accession number: Q5PQP1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: January 4, 2005
Last modified: June 8, 2016
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.