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Protein

Kidney mitochondrial carrier protein 1

Gene

Slc25a30

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable transporter.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Kidney mitochondrial carrier protein 1
Alternative name(s):
Solute carrier family 25 member 30
Gene namesi
Name:Slc25a30
Synonyms:Kmcp1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi1359702. Slc25a30.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 26Helical; Name=1Sequence analysisAdd BLAST18
Transmembranei71 – 89Helical; Name=2Sequence analysisAdd BLAST19
Transmembranei106 – 124Helical; Name=3Sequence analysisAdd BLAST19
Transmembranei164 – 183Helical; Name=4Sequence analysisAdd BLAST20
Transmembranei204 – 224Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei264 – 283Helical; Name=6Sequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002889192 – 291Kidney mitochondrial carrier protein 1Add BLAST290

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiQ5PQM9.

Interactioni

Subunit structurei

Interacts with VDAC1.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ5PQM9.
SMRiQ5PQM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati7 – 96Solcar 1Add BLAST90
Repeati104 – 189Solcar 2Add BLAST86
Repeati198 – 289Solcar 3Add BLAST92

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000165140.
HOVERGENiHBG009528.
InParanoidiQ5PQM9.
KOiK15106.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom_sf.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5PQM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALNWKPFV YGGLASITAE CGTFPIDLTK TRLQIQGQTN DAKFREIRYR
60 70 80 90 100
GMLHALMRIG REEGLRALYS GIAPAMLRQA SYGTIKIGTY QSLKRLAVER
110 120 130 140 150
PEDETLLINV VCGILSGVIS SAIANPTDVL KIRMQAQNSA VQGGMIGNFI
160 170 180 190 200
SIYQQEGTRG LWKGVSLTAQ RAAIVVGVEL PVYDITKKHL ILSGLMGDTV
210 220 230 240 250
STHFLSSFTC GLVGALASNP VDVVRTRMMN QRDLRDGRCS GYKGTLDCLL
260 270 280 290
QTWKNEGFFA LYKGFWPNWL RLGPWNIIFF LTYEQLKKLD L
Length:291
Mass (Da):32,365
Last modified:January 4, 2005 - v1
Checksum:i9F405B9F36DE9702
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087106 mRNA. Translation: AAH87106.1.
RefSeqiNP_001013205.1. NM_001013187.1.
UniGeneiRn.19440.

Genome annotation databases

GeneIDi361074.
KEGGirno:361074.
UCSCiRGD:1359702. rat.

Similar proteinsi

Entry informationi

Entry nameiKMCP1_RAT
AccessioniPrimary (citable) accession number: Q5PQM9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: January 4, 2005
Last modified: November 22, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families