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Protein

Melanoma-associated antigen H1

Gene

Mageh1

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • neurotrophin TRK receptor signaling pathway Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

Tumor antigen

Names & Taxonomyi

Protein namesi
Recommended name:
Melanoma-associated antigen H1
Alternative name(s):
MAGE-H1 antigen
Gene namesi
Name:Mageh1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1359316. Mageh1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 218218Melanoma-associated antigen H1PRO_0000156737Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei194 – 1941PhosphotyrosineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5PPP4.

PTM databases

iPTMnetiQ5PPP4.
PhosphoSiteiQ5PPP4.

Expressioni

Gene expression databases

GenevisibleiQ5PPP4. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000004238.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 197197MAGEPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 MAGE domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4562. Eukaryota.
ENOG4111S70. LUCA.
GeneTreeiENSGT00840000130063.
HOGENOMiHOG000059579.
HOVERGENiHBG052399.
InParanoidiQ5PPP4.
OMAiARSNFQG.
OrthoDBiEOG75F4GM.
PhylomeDBiQ5PPP4.
TreeFamiTF328505.

Family and domain databases

InterProiIPR002190. MHD_dom.
[Graphical view]
PfamiPF01454. MAGE. 1 hit.
[Graphical view]
SMARTiSM01373. MAGE. 1 hit.
[Graphical view]
PROSITEiPS50838. MAGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5PPP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRGRKSRRR RNAKAAEENR NNRKIQASEA SKTPMAASVT PSTPEEYLSG
60 70 80 90 100
PEEDTSTPEK ASSTLAEASS TALVQKPVTR SNFQGTKKSL LMSILALIFI
110 120 130 140 150
MGNSAKEALV WKVLGKLGMQ PGRQHSIFGD PKKVVTEEFV RRGYLIYKPV
160 170 180 190 200
PRSSPVEYEF FWGPRAHVES SKLKVMHFVA RVRNRCSKDW PCNYDWDSDD
210
DAEVEAILNS GARGSSAP
Length:218
Mass (Da):24,289
Last modified:January 4, 2005 - v1
Checksum:iA9756275DC49B3A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087574 mRNA. Translation: AAH87574.1.
RefSeqiNP_001013268.1. NM_001013250.1.
UniGeneiRn.56595.

Genome annotation databases

EnsembliENSRNOT00000004238; ENSRNOP00000004238; ENSRNOG00000003178.
GeneIDi367767.
KEGGirno:367767.
UCSCiRGD:1359316. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087574 mRNA. Translation: AAH87574.1.
RefSeqiNP_001013268.1. NM_001013250.1.
UniGeneiRn.56595.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000004238.

PTM databases

iPTMnetiQ5PPP4.
PhosphoSiteiQ5PPP4.

Proteomic databases

PaxDbiQ5PPP4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000004238; ENSRNOP00000004238; ENSRNOG00000003178.
GeneIDi367767.
KEGGirno:367767.
UCSCiRGD:1359316. rat.

Organism-specific databases

CTDi28986.
RGDi1359316. Mageh1.

Phylogenomic databases

eggNOGiKOG4562. Eukaryota.
ENOG4111S70. LUCA.
GeneTreeiENSGT00840000130063.
HOGENOMiHOG000059579.
HOVERGENiHBG052399.
InParanoidiQ5PPP4.
OMAiARSNFQG.
OrthoDBiEOG75F4GM.
PhylomeDBiQ5PPP4.
TreeFamiTF328505.

Miscellaneous databases

NextBioi691578.
PROiQ5PPP4.

Gene expression databases

GenevisibleiQ5PPP4. RN.

Family and domain databases

InterProiIPR002190. MHD_dom.
[Graphical view]
PfamiPF01454. MAGE. 1 hit.
[Graphical view]
SMARTiSM01373. MAGE. 1 hit.
[Graphical view]
PROSITEiPS50838. MAGE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.
  2. "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
    Hoffert J.D., Pisitkun T., Wang G., Shen R.-F., Knepper M.A.
    Proc. Natl. Acad. Sci. U.S.A. 103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-194, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiMAGH1_RAT
AccessioniPrimary (citable) accession number: Q5PPP4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: January 4, 2005
Last modified: May 11, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.