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Protein
Submitted name:

Gart protein

Gene

Gart

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: UniProtKB-UniRule
  • metal ion binding Source: InterPro
  • phosphoribosylamine-glycine ligase activity Source: RGD
  • phosphoribosylformylglycinamidine cyclo-ligase activity Source: RGD
  • phosphoribosylglycinamide formyltransferase activity Source: RGD

GO - Biological processi

  • brainstem development Source: RGD
  • cerebellum development Source: RGD
  • cerebral cortex development Source: RGD
  • cobalamin metabolic process Source: RGD
  • glycine metabolic process Source: RGD
  • purine nucleobase biosynthetic process Source: InterPro
  • response to inorganic substance Source: RGD
  • response to organic substance Source: RGD
  • ribonucleoside monophosphate biosynthetic process Source: RGD
  • tetrahydrofolate biosynthetic process Source: RGD

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Gart proteinImported
Gene namesi
Name:GartImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1308717. Gart.

PTM / Processingi

Proteomic databases

PaxDbiQ5PPK3.
PRIDEiQ5PPK3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000028292.

Structurei

3D structure databases

ProteinModelPortaliQ5PPK3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 318ATP-graspInterPro annotationAdd BLAST208

Phylogenomic databases

eggNOGiKOG0237. Eukaryota.
KOG3076. Eukaryota.
COG0150. LUCA.
COG0151. LUCA.
COG0299. LUCA.
HOVERGENiHBG053903.
PhylomeDBiQ5PPK3.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.90.600.10. 1 hit.
HAMAPiMF_00138. GARS. 1 hit.
InterProiView protein in InterPro
IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR016185. PreATP-grasp_dom.
IPR020561. PRibGlycinamid_synth_ATP-grasp.
IPR000115. PRibGlycinamide_synth.
IPR020560. PRibGlycinamide_synth_C-dom.
IPR020559. PRibGlycinamide_synth_CS.
IPR020562. PRibGlycinamide_synth_N.
IPR011054. Rudment_hybrid_motif.
PfamiView protein in Pfam
PF01071. GARS_A. 1 hit.
PF02843. GARS_C. 1 hit.
PF02844. GARS_N. 1 hit.
SMARTiView protein in SMART
SM01210. GARS_C. 1 hit.
SUPFAMiSSF51246. SSF51246. 1 hit.
SSF52440. SSF52440. 1 hit.
TIGRFAMsiTIGR00877. purD. 1 hit.
PROSITEiView protein in PROSITE
PS50975. ATP_GRASP. 1 hit.
PS00184. GARS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5PPK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARVLVIGS GGREHTLAWK LAQSPHVKQV LVAPGNAGTA SAGKISNAAV
60 70 80 90 100
SINDHTALAR FCKDEKIELV VVGPEAPLAA GIVGDLTSAG VRCFGPTAQA
110 120 130 140 150
ALLESSKKFA KEFMDRHGVP TAQWRAFTSP EDACSFIMSA DFPALVVKAS
160 170 180 190 200
GLAAGKGVIV AKSKAEACEA VQEIMQEKSF GAAGETVVVE ELLEGEEVSC
210 220 230 240 250
LCFTDGKTVA PMPPAQDHKR LLDGDRGPNT GGMGAYCPAP QVPKDLLVKI
260 270 280 290 300
KNTILQRTVD GMQQEGVPYT GILYAGIMLT KDGPKVLEFN CRFGDPECQV
310 320 330 340 350
ILPLLKSDLY EVIQSTFDGL LSESPPVWLE NHSAVTVVMA SGGYPGAYTK
360 370 380 390 400
GVEITGFPEA QALGLQVFHA GTALKDAKVV TSGGRVLTVT AVRENLMSAL
410 420 430
DEARKGLAAL KFEGAVYRKD IGFRAVAFLQ RPR
Length:433
Mass (Da):45,711
Last modified:January 4, 2005 - v1
Checksum:iBB01FCA60E0BE3FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087644 mRNA. Translation: AAH87644.1.
UniGeneiRn.55532.

Genome annotation databases

UCSCiRGD:1308717. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5PPK3_RAT
AccessioniPrimary (citable) accession number: Q5PPK3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: July 5, 2017
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)