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Q5PPK3

- Q5PPK3_RAT

UniProt

Q5PPK3 - Q5PPK3_RAT

Protein
Submitted name:

Gart protein

Gene

Gart

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (04 Jan 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. metal ion binding Source: InterPro
    3. phosphoribosylamine-glycine ligase activity Source: RGD
    4. phosphoribosylformylglycinamidine cyclo-ligase activity Source: RGD
    5. phosphoribosylglycinamide formyltransferase activity Source: RGD

    GO - Biological processi

    1. brainstem development Source: RGD
    2. cerebellum development Source: RGD
    3. cerebral cortex development Source: RGD
    4. cobalamin metabolic process Source: RGD
    5. glycine metabolic process Source: RGD
    6. purine nucleobase biosynthetic process Source: InterPro
    7. response to inorganic substance Source: RGD
    8. response to organic substance Source: RGD
    9. ribonucleoside monophosphate biosynthetic process Source: RGD
    10. tetrahydrofolate biosynthetic process Source: RGD

    Enzyme and pathway databases

    ReactomeiREACT_217264. Purine ribonucleoside monophosphate biosynthesis.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Gart proteinImported
    Gene namesi
    Name:GartImported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi1308717. Gart.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5PPK3.

    Expressioni

    Gene expression databases

    GenevestigatoriQ5PPK3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5PPK3.
    SMRiQ5PPK3. Positions 1-430.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG053903.
    InParanoidiQ5PPK3.
    PhylomeDBiQ5PPK3.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.20. 1 hit.
    3.90.600.10. 1 hit.
    HAMAPiMF_00138. GARS.
    InterProiIPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR016185. PreATP-grasp_dom.
    IPR020561. PRibGlycinamid_synth_ATP-grasp.
    IPR000115. PRibGlycinamide_synth.
    IPR020560. PRibGlycinamide_synth_C-dom.
    IPR020559. PRibGlycinamide_synth_CS.
    IPR020562. PRibGlycinamide_synth_N.
    IPR011054. Rudment_hybrid_motif.
    [Graphical view]
    PfamiPF01071. GARS_A. 1 hit.
    PF02843. GARS_C. 1 hit.
    PF02844. GARS_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF51246. SSF51246. 1 hit.
    SSF52440. SSF52440. 1 hit.
    TIGRFAMsiTIGR00877. purD. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    PS00184. GARS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5PPK3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAARVLVIGS GGREHTLAWK LAQSPHVKQV LVAPGNAGTA SAGKISNAAV    50
    SINDHTALAR FCKDEKIELV VVGPEAPLAA GIVGDLTSAG VRCFGPTAQA 100
    ALLESSKKFA KEFMDRHGVP TAQWRAFTSP EDACSFIMSA DFPALVVKAS 150
    GLAAGKGVIV AKSKAEACEA VQEIMQEKSF GAAGETVVVE ELLEGEEVSC 200
    LCFTDGKTVA PMPPAQDHKR LLDGDRGPNT GGMGAYCPAP QVPKDLLVKI 250
    KNTILQRTVD GMQQEGVPYT GILYAGIMLT KDGPKVLEFN CRFGDPECQV 300
    ILPLLKSDLY EVIQSTFDGL LSESPPVWLE NHSAVTVVMA SGGYPGAYTK 350
    GVEITGFPEA QALGLQVFHA GTALKDAKVV TSGGRVLTVT AVRENLMSAL 400
    DEARKGLAAL KFEGAVYRKD IGFRAVAFLQ RPR 433
    Length:433
    Mass (Da):45,711
    Last modified:January 4, 2005 - v1
    Checksum:iBB01FCA60E0BE3FB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC087644 mRNA. Translation: AAH87644.1.
    UniGeneiRn.55532.

    Genome annotation databases

    UCSCiRGD:1308717. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC087644 mRNA. Translation: AAH87644.1 .
    UniGenei Rn.55532.

    3D structure databases

    ProteinModelPortali Q5PPK3.
    SMRi Q5PPK3. Positions 1-430.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5PPK3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi RGD:1308717. rat.

    Organism-specific databases

    RGDi 1308717. Gart.

    Phylogenomic databases

    HOVERGENi HBG053903.
    InParanoidi Q5PPK3.
    PhylomeDBi Q5PPK3.

    Enzyme and pathway databases

    Reactomei REACT_217264. Purine ribonucleoside monophosphate biosynthesis.

    Gene expression databases

    Genevestigatori Q5PPK3.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.20. 1 hit.
    3.90.600.10. 1 hit.
    HAMAPi MF_00138. GARS.
    InterProi IPR011761. ATP-grasp.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR016185. PreATP-grasp_dom.
    IPR020561. PRibGlycinamid_synth_ATP-grasp.
    IPR000115. PRibGlycinamide_synth.
    IPR020560. PRibGlycinamide_synth_C-dom.
    IPR020559. PRibGlycinamide_synth_CS.
    IPR020562. PRibGlycinamide_synth_N.
    IPR011054. Rudment_hybrid_motif.
    [Graphical view ]
    Pfami PF01071. GARS_A. 1 hit.
    PF02843. GARS_C. 1 hit.
    PF02844. GARS_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51246. SSF51246. 1 hit.
    SSF52440. SSF52440. 1 hit.
    TIGRFAMsi TIGR00877. purD. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    PS00184. GARS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: BrainImported.

    Entry informationi

    Entry nameiQ5PPK3_RAT
    AccessioniPrimary (citable) accession number: Q5PPK3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 4, 2005
    Last sequence update: January 4, 2005
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)