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Protein

Zinc finger protein 414

Gene

Znf414

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 123C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri135 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri166 – 190C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 414
Gene namesi
Name:Znf414
Synonyms:Zfp414
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1308123. Zfp414.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421651 – 299Zinc finger protein 414Add BLAST299

Proteomic databases

PaxDbiQ5PPH4.

Expressioni

Gene expression databases

BgeeiENSRNOG00000008378.
GenevisibleiQ5PPH4. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011094.

Structurei

3D structure databases

ProteinModelPortaliQ5PPH4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi195 – 267Pro-richAdd BLAST73

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 123C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri135 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri166 – 190C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00390000006876.
HOGENOMiHOG000015387.
HOVERGENiHBG083015.
InParanoidiQ5PPH4.
OMAiEGECPVF.
OrthoDBiEOG091G0DB2.
PhylomeDBiQ5PPH4.
TreeFamiTF337512.

Family and domain databases

InterProiView protein in InterPro
IPR031799. Znf-C2H2_ribbon.
IPR013087. Znf_C2H2_type.
PfamiView protein in Pfam
PF15909. zf-C2H2_8. 1 hit.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 3 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.

Sequencei

Sequence statusi: Complete.

Q5PPH4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEELSGPSSD TLATVESSSN EPDKEVASPD VAATATLSSV EEPGPNPTAT
60 70 80 90 100
PPVWDRGGPL QQVACPVPDS CQTSSTTRGV GTNEDLRLPR RRPPPGKQIP
110 120 130 140 150
CSSPGCSLSF PSVRDLAQHL RTHCPPTQSL EGKLFRCSAL SCTESFPSMQ
160 170 180 190 200
ELVAHGKLHY KPNRYFKCEN CLLRFRTHRS LFKHLHVCID HGQNPAPPPP
210 220 230 240 250
PALDKEPPVP ERPPESDPSS SLGLPFPLLE PFTSAPTGPF LPYLNPAPFG
260 270 280 290
LSPPRLRPFL AATPGPPTSS TAIWKKSQGA TSSPRRPQGG SDAPSGACR
Length:299
Mass (Da):31,967
Last modified:January 4, 2005 - v1
Checksum:i0988FF9C3263345B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087693 mRNA. Translation: AAH87693.1.
RefSeqiNP_001009664.1. NM_001009664.1.
UniGeneiRn.32868.

Genome annotation databases

EnsembliENSRNOT00000011094; ENSRNOP00000011094; ENSRNOG00000008378.
GeneIDi299647.
KEGGirno:299647.
UCSCiRGD:1308123. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiZN414_RAT
AccessioniPrimary (citable) accession number: Q5PPH4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: January 4, 2005
Last modified: May 10, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families