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Protein
Submitted name:

Hrh3 protein

Gene

Hrh3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Hrh3 proteinImported
Gene namesi
Name:Hrh3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi620630. Hrh3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei35 – 60HelicalSequence analysisAdd BLAST26
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Transmembranei112 – 135HelicalSequence analysisAdd BLAST24
Transmembranei156 – 176HelicalSequence analysisAdd BLAST21
Transmembranei196 – 223HelicalSequence analysisAdd BLAST28
Transmembranei308 – 332HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ5PPG3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000008080.

Interactioni

Chemistry databases

BindingDBiQ5PPG3.

Structurei

3D structure databases

ProteinModelPortaliQ5PPG3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 344G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST294

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG102132.
KOiK04151.

Family and domain databases

InterProiView protein in InterPro
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR003980. Histamine_H3_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00237. GPCRRHODOPSN.
PR01471. HISTAMINEH3R.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5PPG3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERAPPDGLM NASGTLAGEA AAAGGARGFS AAWTAVLAAL MALLIVATVL
60 70 80 90 100
GNALVMLAFV ADSSLRTQNN FFLLNLAISD FLVGAFCIPL YVPYVLTGRW
110 120 130 140 150
TFGRGLCKLW LVVDYLLCAS SVFNIVLISY DRFLSVTRAV SYRAQQGDTR
160 170 180 190 200
RAVRKMALVW VLAFLLYGPA ILSWEYLSGG SSIPEGHCYA EFFYNWYFLI
210 220 230 240 250
TASTLEFFTP FLSVTFFNLS IYLNIQRRTR LRLDGGREAG PEPPPDAQPS
260 270 280 290 300
PPPAPPSCWG CWPKGHGEAM PLHRGSKPSA SSASLEKRMK MVSQSITQRF
310 320 330 340
RLSRDKKVAK SLAIIVSIFG LCWAPYTLLM IIRAACHGRC IPDY
Length:344
Mass (Da):37,847
Last modified:January 4, 2005 - v1
Checksum:i45D3222BB895FE40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC087707 mRNA. Translation: AAH87707.1.
RefSeqiNP_001257493.1. NM_001270564.1.
NP_001257494.1. NM_001270565.1.
NP_001257495.1. NM_001270566.1.
NP_001257496.1. NM_001270567.1.
NP_001257497.1. NM_001270568.1.
NP_001257498.1. NM_001270569.1.
NP_001257499.1. NM_001270570.1.
NP_445958.1. NM_053506.2.
UniGeneiRn.7617.

Genome annotation databases

GeneIDi85268.
KEGGirno:85268.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5PPG3_RAT
AccessioniPrimary (citable) accession number: Q5PPG3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 4, 2005
Last sequence update: January 4, 2005
Last modified: July 5, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)