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Protein

Probable protein phosphatase 2C 64

Gene

At4g38520

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi86Manganese 1By similarity1
Metal bindingi86Manganese 2By similarity1
Metal bindingi87Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi287Manganese 2By similarity1
Metal bindingi346Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 64 (EC:3.1.3.16)
Short name:
AtPP2C64
Gene namesi
Ordered Locus Names:At4g38520
ORF Names:F20M13.80
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G38520.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679861 – 400Probable protein phosphatase 2C 64Add BLAST400

Proteomic databases

PaxDbiQ5PNS9.

Expressioni

Gene expression databases

GenevisibleiQ5PNS9. AT.

Interactioni

Protein-protein interaction databases

BioGridi15289. 3 interactors.
IntActiQ5PNS9. 1 interactor.
MINTiMINT-8390433.
STRINGi3702.AT4G38520.1.

Structurei

3D structure databases

ProteinModelPortaliQ5PNS9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 355PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST309

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000238703.
InParanoidiQ5PNS9.
OMAiCMSSEVI.
OrthoDBiEOG09360D2T.
PhylomeDBiQ5PNS9.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5PNS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSGLMNFLN ACLWPRSDQQ ARSASDSGGR QEGLLWFRDS GQHVFGDFSM
60 70 80 90 100
AVVQANSLLE DQSQLESGSL SSHDSGPFGT FVGVYDGHGG PETSRFINDH
110 120 130 140 150
MFHHLKRFTA EQQCMSSEVI KKAFQATEEG FLSIVTNQFQ TRPQIATVGS
160 170 180 190 200
CCLVSVICDG KLYVANAGDS RAVLGQVMRV TGEAHATQLS AEHNASIESV
210 220 230 240 250
RRELQALHPD HPDIVVLKHN VWRVKGIIQV SRSIGDVYLK RSEFNREPLY
260 270 280 290 300
AKFRLRSPFS KPLLSAEPAI TVHTLEPHDQ FIICASDGLW EHMSNQEAVD
310 320 330 340 350
IVQNHPRNGI AKRLVKVALQ EAAKKREMRY SDLKKIDRGV RRHFHDDITV
360 370 380 390 400
IVVFFDTNLV SRGSMLRGPA VSVRGAGVNL PHNTLAPCTT PTQAAAAGAS
Length:400
Mass (Da):44,123
Last modified:January 4, 2005 - v1
Checksum:i66AA091D20562CE3
GO

Sequence cautioni

The sequence CAB37508 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAB80516 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38R → S in AAL32532 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035540 Genomic DNA. Translation: CAB37508.1. Different initiation.
AL161593 Genomic DNA. Translation: CAB80516.1. Different initiation.
CP002687 Genomic DNA. Translation: AEE86941.1.
CP002687 Genomic DNA. Translation: AEE86942.1.
AY062454 mRNA. Translation: AAL32532.1.
BT020368 mRNA. Translation: AAV85723.1.
BT021094 mRNA. Translation: AAX12864.1.
PIRiT05680.
RefSeqiNP_195564.2. NM_120013.6.
NP_974708.1. NM_202979.1.
UniGeneiAt.47543.

Genome annotation databases

EnsemblPlantsiAT4G38520.1; AT4G38520.1; AT4G38520.
AT4G38520.2; AT4G38520.2; AT4G38520.
GeneIDi830009.
GrameneiAT4G38520.1; AT4G38520.1; AT4G38520.
AT4G38520.2; AT4G38520.2; AT4G38520.
KEGGiath:AT4G38520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL035540 Genomic DNA. Translation: CAB37508.1. Different initiation.
AL161593 Genomic DNA. Translation: CAB80516.1. Different initiation.
CP002687 Genomic DNA. Translation: AEE86941.1.
CP002687 Genomic DNA. Translation: AEE86942.1.
AY062454 mRNA. Translation: AAL32532.1.
BT020368 mRNA. Translation: AAV85723.1.
BT021094 mRNA. Translation: AAX12864.1.
PIRiT05680.
RefSeqiNP_195564.2. NM_120013.6.
NP_974708.1. NM_202979.1.
UniGeneiAt.47543.

3D structure databases

ProteinModelPortaliQ5PNS9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi15289. 3 interactors.
IntActiQ5PNS9. 1 interactor.
MINTiMINT-8390433.
STRINGi3702.AT4G38520.1.

Proteomic databases

PaxDbiQ5PNS9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G38520.1; AT4G38520.1; AT4G38520.
AT4G38520.2; AT4G38520.2; AT4G38520.
GeneIDi830009.
GrameneiAT4G38520.1; AT4G38520.1; AT4G38520.
AT4G38520.2; AT4G38520.2; AT4G38520.
KEGGiath:AT4G38520.

Organism-specific databases

TAIRiAT4G38520.

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000238703.
InParanoidiQ5PNS9.
OMAiCMSSEVI.
OrthoDBiEOG09360D2T.
PhylomeDBiQ5PNS9.

Miscellaneous databases

PROiQ5PNS9.

Gene expression databases

GenevisibleiQ5PNS9. AT.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 2 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C64_ARATH
AccessioniPrimary (citable) accession number: Q5PNS9
Secondary accession number(s): Q8W4N8, Q9SZN2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: January 4, 2005
Last modified: November 30, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.